| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | 0.199179 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.129607 |
| MT2A | metallothionein 2A | 0.114443 |
| EGR1 | early growth response 1 | 0.104976 |
| ACTG1 | actin gamma 1 | 0.102098 |
| CD109 | CD109 molecule | 0.0995958 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0934543 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0845841 |
| RUNX1 | runt-related transcription factor 1 | 0.0828608 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0816327 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0804228 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0802001 |
| FN1 | fibronectin 1 | 0.07687 |
| FMNL2 | formin-like 2 | 0.0718243 |
| HLA-B | major histocompatibility complex, class I, B | 0.0712376 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0692645 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0660309 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.064344 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0623867 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0593663 |
| JUN | jun proto-oncogene | 0.0579173 |
| MCL1 | myeloid cell leukemia 1 | 0.0553669 |
| ADM | adrenomedullin | 0.0542338 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0532543 |
| NAV2 | neuron navigator 2 | 0.0522326 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0520997 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0514666 |
| PARVB | parvin, beta | 0.0489783 |
| ENO1 | enolase 1, (alpha) | 0.0474911 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0467808 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0465968 |
| NDRG1 | N-myc downstream regulated 1 | 0.0450314 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0448742 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0439041 |
| MYO1E | myosin IE | 0.0429703 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0429004 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.042832 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0427493 |
| CTTNBP2 | cortactin binding protein 2 | 0.0420588 |
| NAV1 | neuron navigator 1 | 0.0418814 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0417835 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0415797 |
| ZNF638 | zinc finger protein 638 | 0.0411243 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0409404 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0409364 |
| MT1X | metallothionein 1X | 0.0397564 |
| CABIN1 | calcineurin binding protein 1 | 0.0389113 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0386496 |
| ITGB8 | integrin, beta 8 | 0.0386464 |
| CLMN | calmin (calponin-like, transmembrane) | 0.038494 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.03787 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0369857 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0369303 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0367164 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0363962 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0363395 |
| SETBP1 | SET binding protein 1 | 0.0354701 |
| GANAB | glucosidase, alpha; neutral AB | 0.0353406 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0347571 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0337751 |
| RCAN1 | regulator of calcineurin 1 | 0.0337134 |
| CSNK1E | casein kinase 1, epsilon | 0.0333659 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0332224 |
| STRIP2 | striatin interacting protein 2 | 0.0331076 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0329398 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0323321 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0321623 |
| LMNA | lamin A/C | 0.0315209 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0314119 |
| AFDN | afadin, adherens junction formation factor | 0.0306762 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0306344 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0298857 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0297099 |
| HLA-A | major histocompatibility complex, class I, A | 0.029544 |
| RPL28 | ribosomal protein L28 | 0.0293886 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0293688 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0292395 |
| RAD51B | RAD51 paralog B | 0.0290504 |
| ARFGEF3 | ARFGEF family member 3 | 0.0290057 |
| ACTN1 | actinin, alpha 1 | 0.0286053 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0285991 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.028551 |
| SSBP3 | single stranded DNA binding protein 3 | 0.028053 |
| USP37 | ubiquitin specific peptidase 37 | 0.0278119 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0276133 |
| RPS12 | ribosomal protein S12 | 0.0275344 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0270329 |
| SEPTIN9 | septin 9 | 0.02668 |
| RPL37A | ribosomal protein L37a | 0.0266129 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0266001 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 0.0265967 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0264974 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0264066 |
| RPS8 | ribosomal protein S8 | 0.0263402 |
| FLNB | filamin B, beta | 0.0259265 |
| RPL27 | ribosomal protein L27 | 0.025748 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0255769 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0255653 |
| ACTN4 | actinin, alpha 4 | 0.0255602 |
| FRMD4A | FERM domain containing 4A | 0.0255426 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.310714 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.150443 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.147744 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.109498 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.106854 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.101886 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.082022 |
| ASPH | aspartate beta-hydroxylase | -0.0782891 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0778278 |
| CENPF | centromere protein F, 350/400kDa | -0.0762309 |
| DCT | dopachrome tautomerase | -0.0709845 |
| FMN1 | formin 1 | -0.0695751 |
| VGF | VGF nerve growth factor inducible | -0.0656383 |
| TMEM123 | transmembrane protein 123 | -0.061032 |
| CANX | calnexin | -0.0603755 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0587317 |
| PHF21A | PHD finger protein 21A | -0.0586441 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0543391 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0525561 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0521568 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0498003 |
| CDC73 | cell division cycle 73 | -0.0483717 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0473856 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0461671 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0461193 |
| AHNAK | AHNAK nucleoprotein | -0.0459912 |
| A2M | alpha-2-macroglobulin | -0.0458015 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0442052 |
| CALR | calreticulin | -0.0436869 |
| CALD1 | caldesmon 1 | -0.0430938 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0428918 |
| AHR | aryl hydrocarbon receptor | -0.0428225 |
| PGK1 | phosphoglycerate kinase 1 | -0.0419271 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0414441 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.040985 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0389223 |
| RO60 | Ro60, Y RNA binding protein | -0.0380967 |
| MATR3 | matrin 3 | -0.0364418 |
| LAMB1 | laminin, beta 1 | -0.0358644 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0349878 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0340805 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0339461 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0336438 |
| TRIM2 | tripartite motif containing 2 | -0.0333648 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0332835 |
| TMEM178B | transmembrane protein 178B | -0.0331367 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.032728 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0324851 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0324453 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0317861 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0316163 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0311846 |
| IL6ST | interleukin 6 signal transducer | -0.0307153 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0305687 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0299194 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0298252 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0294019 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0292235 |
| CLTC | clathrin, heavy chain (Hc) | -0.0280182 |
| PI15 | peptidase inhibitor 15 | -0.0279929 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0277203 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0277154 |
| TNNC1 | troponin C type 1 (slow) | -0.0275079 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.027494 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0269905 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0269313 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0266419 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0265156 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0264623 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0264284 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0264168 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0263424 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0262992 |
| NUP58 | nucleoporin 58 | -0.02626 |
| GDF15 | growth differentiation factor 15 | -0.0260911 |
| TMSB10 | thymosin beta 10 | -0.0260706 |
| RNF145 | ring finger protein 145 | -0.0259585 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0259467 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0258449 |
| TKT | transketolase | -0.0258439 |
| BBX | bobby sox homolog (Drosophila) | -0.0257723 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0255431 |
| CD63 | CD63 molecule | -0.0255333 |
| XPO1 | exportin 1 | -0.0249079 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0248961 |
| PDE10A | phosphodiesterase 10A | -0.024731 |
| MKI67 | marker of proliferation Ki-67 | -0.0244918 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0244729 |
| DSTYK | dual serine/threonine and tyrosine protein kinase | -0.0239594 |
| MYO10 | myosin X | -0.0238864 |
| GOLGA4 | golgin A4 | -0.0238719 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0237559 |
| COG5 | component of oligomeric golgi complex 5 | -0.0237038 |
| NBAS | neuroblastoma amplified sequence | -0.0236789 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0235409 |
| OGA | O-GlcNAcase | -0.023348 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0233384 |
| CLINT1 | clathrin interactor 1 | -0.023255 |
| AK4 | adenylate kinase 4 | -0.0232414 |
| PKM | pyruvate kinase, muscle | -0.0231147 |
