| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.197475 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.155328 |
| TGM2 | transglutaminase 2 | 0.134061 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.113275 |
| APOL1 | apolipoprotein L, 1 | 0.111151 |
| MT2A | metallothionein 2A | 0.105701 |
| KRT19 | keratin 19, type I | 0.102477 |
| FNDC3B | fibronectin type III domain containing 3B | 0.094598 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0881279 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0794458 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.073735 |
| SMAD3 | SMAD family member 3 | 0.0677982 |
| HLA-A | major histocompatibility complex, class I, A | 0.0665858 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0616921 |
| B2M | beta-2-microglobulin | 0.0614997 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0576709 |
| LAMA4 | laminin, alpha 4 | 0.0567833 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.056244 |
| LCN2 | lipocalin 2 | 0.0528218 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0496655 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.04845 |
| EFNA5 | ephrin-A5 | 0.0478991 |
| NDRG1 | N-myc downstream regulated 1 | 0.0476478 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0456033 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0445225 |
| SGMS2 | sphingomyelin synthase 2 | 0.0443775 |
| VEGFA | vascular endothelial growth factor A | 0.0440264 |
| MYO1E | myosin IE | 0.0422429 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0420192 |
| RAD51B | RAD51 paralog B | 0.0413785 |
| RNF213 | ring finger protein 213 | 0.0403158 |
| H1-0 | H1.0 linker histone | 0.0392839 |
| CSTB | cystatin B (stefin B) | 0.0387381 |
| SEPTIN9 | septin 9 | 0.038662 |
| MCL1 | myeloid cell leukemia 1 | 0.0383324 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0374315 |
| C3 | complement component 3 | 0.0373593 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0372281 |
| EGR1 | early growth response 1 | 0.0369538 |
| RPS6 | ribosomal protein S6 | 0.0366298 |
| HLA-B | major histocompatibility complex, class I, B | 0.0365572 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0357978 |
| JUP | junction plakoglobin | 0.0343128 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0343029 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0342324 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0341295 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0332005 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0330857 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0329092 |
| MUC1 | mucin 1, cell surface associated | 0.0316043 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0314364 |
| TMEM51 | transmembrane protein 51 | 0.0311926 |
| PLEC | plectin | 0.0307818 |
| TMC5 | transmembrane channel-like 5 | 0.0301743 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0300819 |
| DUSP5 | dual specificity phosphatase 5 | 0.0300789 |
| CMIP | c-Maf inducing protein | 0.0300435 |
| FTL | ferritin, light polypeptide | 0.0294584 |
| AGRN | agrin | 0.0294517 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0294034 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0291986 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0289059 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.028867 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0286432 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0286394 |
| FHL2 | four and a half LIM domains 2 | 0.0283907 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.027534 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0274975 |
| CP | ceruloplasmin (ferroxidase) | 0.0270734 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0269531 |
| ECE1 | endothelin converting enzyme 1 | 0.026892 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0266053 |
| BCL2L1 | BCL2-like 1 | 0.0263085 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262961 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0260596 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0258167 |
| MT1E | metallothionein 1E | 0.0257603 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0255151 |
| FOSL1 | FOS-like antigen 1 | 0.025346 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0252128 |
| MX2 | MX dynamin-like GTPase 2 | 0.0251619 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0251275 |
| MX1 | MX dynamin-like GTPase 1 | 0.0250716 |
| NOTCH2 | notch 2 | 0.0245875 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0241852 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0240497 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0239787 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0237154 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0233106 |
| STC1 | stanniocalcin 1 | 0.0232768 |
| CD44 | CD44 molecule (Indian blood group) | 0.022733 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0227195 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0226842 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0223219 |
| TXNIP | thioredoxin interacting protein | 0.0221562 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0221506 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0219956 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0216578 |
| RPS2 | ribosomal protein S2 | 0.021588 |
| BRD2 | bromodomain containing 2 | 0.0213865 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.091627 |
| TMSB4X | thymosin beta 4, X-linked | -0.0885697 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0841567 |
| TMSB10 | thymosin beta 10 | -0.0812086 |
| UBC | ubiquitin C | -0.0787534 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0739215 |
| PTMA | prothymosin, alpha | -0.0718548 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0678331 |
| MMP7 | matrix metallopeptidase 7 | -0.0649352 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0554157 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0490453 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0422555 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0422442 |
| PGK1 | phosphoglycerate kinase 1 | -0.0409404 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0407135 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0405496 |
| LMO7 | LIM domain 7 | -0.0405183 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0401809 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0398213 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0388867 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0385968 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0374879 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0369313 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0368089 |
| ACTG1 | actin gamma 1 | -0.0357098 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.035424 |
| ASPH | aspartate beta-hydroxylase | -0.0352974 |
| TMEM123 | transmembrane protein 123 | -0.0348742 |
| RBM39 | RNA binding motif protein 39 | -0.0347149 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.034586 |
| FLNB | filamin B, beta | -0.0331342 |
| AHNAK | AHNAK nucleoprotein | -0.0329867 |
| RPS27A | ribosomal protein S27a | -0.0329314 |
| FRMD5 | FERM domain containing 5 | -0.0322517 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.031952 |
| RASAL2 | RAS protein activator like 2 | -0.0317434 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0314165 |
| CANX | calnexin | -0.0306654 |
| PLAU | plasminogen activator, urokinase | -0.0294604 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0289343 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.028456 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0284131 |
| OGA | O-GlcNAcase | -0.0280822 |
| JMJD1C | jumonji domain containing 1C | -0.0280157 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0279448 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0278489 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0271986 |
| PDLIM5 | PDZ and LIM domain 5 | -0.026897 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0263148 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0262968 |
| COG5 | component of oligomeric golgi complex 5 | -0.0261346 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0258517 |
| SPAG9 | sperm associated antigen 9 | -0.0257461 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0256578 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.025503 |
| ERBIN | erbb2 interacting protein | -0.0254583 |
| RPS24 | ribosomal protein S24 | -0.0252964 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0242771 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0242351 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0241087 |
| KLF6 | Kruppel-like factor 6 | -0.0236384 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0234378 |
| DTNA | dystrobrevin, alpha | -0.023263 |
| EPCAM | epithelial cell adhesion molecule | -0.0232197 |
| TPM1 | tropomyosin 1 (alpha) | -0.0231727 |
| IRF6 | interferon regulatory factor 6 | -0.0229403 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.0229277 |
| LAMC2 | laminin, gamma 2 | -0.0228766 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0228096 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0225452 |
| IER3 | immediate early response 3 | -0.0224376 |
| EREG | epiregulin | -0.0223334 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0222885 |
| FMNL2 | formin-like 2 | -0.0222178 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0221103 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0220535 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0220399 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0218303 |
| RTN4 | reticulon 4 | -0.0218112 |
| CDK6 | cyclin-dependent kinase 6 | -0.0216654 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0216435 |
| NCKAP5 | NCK-associated protein 5 | -0.0215802 |
| RRBP1 | ribosome binding protein 1 | -0.0214228 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0213726 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0213219 |
| MYO6 | myosin VI | -0.0212482 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0211731 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0211503 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0211258 |
| INSIG1 | insulin induced gene 1 | -0.0207046 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0205458 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0205432 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0204908 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0204738 |
| USP15 | ubiquitin specific peptidase 15 | -0.0204244 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0202428 |
| USP53 | ubiquitin specific peptidase 53 | -0.0201338 |
| CLTC | clathrin, heavy chain (Hc) | -0.0199984 |
| CALR | calreticulin | -0.019992 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0199908 |
