| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.148195 |
| LMO7 | LIM domain 7 | 0.127994 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0919559 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0859473 |
| MYO1E | myosin IE | 0.0835026 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0790174 |
| PHF3 | PHD finger protein 3 | 0.0759187 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0723679 |
| ANXA2 | annexin A2 | 0.0633507 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.056843 |
| EGR1 | early growth response 1 | 0.0564556 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0547409 |
| STK24 | serine/threonine kinase 24 | 0.0543237 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0529189 |
| SMAD3 | SMAD family member 3 | 0.0527656 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0515682 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0479795 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0479475 |
| AREG | amphiregulin | 0.04769 |
| TMC5 | transmembrane channel-like 5 | 0.0462108 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0456202 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0443549 |
| MCL1 | myeloid cell leukemia 1 | 0.0442115 |
| DIAPH1 | diaphanous-related formin 1 | 0.0439443 |
| EFNB2 | ephrin-B2 | 0.0430226 |
| MX1 | MX dynamin-like GTPase 1 | 0.0429182 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0426186 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0423718 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0417801 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0417409 |
| PLSCR1 | phospholipid scramblase 1 | 0.04169 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0413665 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0406793 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0406366 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0397614 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0388863 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0375912 |
| TJP1 | tight junction protein 1 | 0.0375426 |
| ACTN4 | actinin, alpha 4 | 0.0367736 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0366037 |
| VCL | vinculin | 0.0355772 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0354043 |
| PDZD8 | PDZ domain containing 8 | 0.0340204 |
| MX2 | MX dynamin-like GTPase 2 | 0.0336202 |
| ACTG1 | actin gamma 1 | 0.0331952 |
| XDH | xanthine dehydrogenase | 0.0319458 |
| POU2F2 | POU class 2 homeobox 2 | 0.0317533 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0311048 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0299461 |
| INTS6 | integrator complex subunit 6 | 0.0298896 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0292637 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0290297 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0286298 |
| ERBIN | erbb2 interacting protein | 0.0285299 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0284604 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0283809 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0265244 |
| MYO5B | myosin VB | 0.026507 |
| BCL2L1 | BCL2-like 1 | 0.0264236 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0261268 |
| SDC4 | syndecan 4 | 0.0260694 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0257851 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0256026 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0255884 |
| SMYD3 | SET and MYND domain containing 3 | 0.0252702 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.025044 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0243194 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0243168 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0241151 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0240366 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0239788 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.023957 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0237966 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0237553 |
| ETV6 | ets variant 6 | 0.0237431 |
| MCU | mitochondrial calcium uniporter | 0.0237411 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0236424 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.023292 |
| TMEM62 | transmembrane protein 62 | 0.0230245 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0230055 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0227779 |
| NEBL | nebulette | 0.0226492 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0225409 |
| RAD51B | RAD51 paralog B | 0.0225111 |
| USP54 | ubiquitin specific peptidase 54 | 0.0224713 |
| RPS12 | ribosomal protein S12 | 0.022283 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0222456 |
| TRIM25 | tripartite motif containing 25 | 0.0218625 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0212994 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0212425 |
| TOP1 | topoisomerase (DNA) I | 0.020991 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.020792 |
| UBE3A | ubiquitin protein ligase E3A | 0.0205941 |
| PSEN1 | presenilin 1 | 0.0205117 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0201989 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0198542 |
| IRS2 | insulin receptor substrate 2 | 0.0198099 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.019545 |
| RNF213 | ring finger protein 213 | 0.0195274 |
| MAP7 | microtubule-associated protein 7 | 0.0194744 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.189973 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.176804 |
| PTMA | prothymosin, alpha | -0.0903408 |
| LYZ | lysozyme | -0.0898285 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0874735 |
| RNF149 | ring finger protein 149 | -0.0767015 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0736591 |
| AHNAK | AHNAK nucleoprotein | -0.0635146 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0608079 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0592214 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0574508 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0571705 |
| TMSB10 | thymosin beta 10 | -0.0566094 |
| ABLIM1 | actin binding LIM protein 1 | -0.0561578 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0534581 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0526698 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0510237 |
| CALR | calreticulin | -0.0493849 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0491093 |
| XAF1 | XIAP associated factor 1 | -0.0484197 |
| FTL | ferritin, light polypeptide | -0.046008 |
| RRBP1 | ribosome binding protein 1 | -0.0450933 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0439211 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0422652 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0421454 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.041664 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0411814 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0406459 |
| RPS24 | ribosomal protein S24 | -0.0406303 |
| B2M | beta-2-microglobulin | -0.0404068 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0403825 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0399528 |
| MT2A | metallothionein 2A | -0.0396377 |
| RBM39 | RNA binding motif protein 39 | -0.0393508 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0387017 |
| MORF4L2 | mortality factor 4 like 2 | -0.0385171 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0379093 |
| RPL35A | ribosomal protein L35a | -0.037707 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.037564 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.036895 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0362257 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0360924 |
| ANXA1 | annexin A1 | -0.036053 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.035927 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0358471 |
| CANX | calnexin | -0.035669 |
| H1-0 | H1.0 linker histone | -0.0355969 |
| MUC20 | mucin 20, cell surface associated | -0.03559 |
| PRELID2 | PRELI domain containing 2 | -0.0354048 |
| FDPS | farnesyl diphosphate synthase | -0.0352431 |
| GOLGA4 | golgin A4 | -0.0350858 |
| FRMD5 | FERM domain containing 5 | -0.0334766 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.033142 |
| NPSR1 | neuropeptide S receptor 1 | -0.0320311 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0319307 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0319294 |
| BRCA2 | breast cancer 2, early onset | -0.0318879 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0318717 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0318446 |
| TJP2 | tight junction protein 2 | -0.0317871 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0310136 |
| SBF2 | SET binding factor 2 | -0.0305974 |
| PTGR1 | prostaglandin reductase 1 | -0.030569 |
| WASF2 | WAS protein family, member 2 | -0.0300586 |
| MKI67 | marker of proliferation Ki-67 | -0.0299838 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0299452 |
| LDHA | lactate dehydrogenase A | -0.0299337 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.0298769 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0298686 |
| CDK6 | cyclin-dependent kinase 6 | -0.0296418 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0295803 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0294307 |
| CLTC | clathrin, heavy chain (Hc) | -0.0292969 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0290491 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0289733 |
| TMEM123 | transmembrane protein 123 | -0.0288594 |
| COG6 | component of oligomeric golgi complex 6 | -0.0283491 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0283271 |
| AGR2 | anterior gradient 2 | -0.0282048 |
| PTEN | phosphatase and tensin homolog | -0.0281092 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0280633 |
| PRKCA | protein kinase C, alpha | -0.0280576 |
| GNAS | GNAS complex locus | -0.0279378 |
| CMIP | c-Maf inducing protein | -0.0279039 |
| DIAPH3 | diaphanous-related formin 3 | -0.0278582 |
| TMEM263 | transmembrane protein 263 | -0.0276658 |
| FANCI | Fanconi anemia, complementation group I | -0.0275731 |
| MT1X | metallothionein 1X | -0.0273888 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.027086 |
| MECOM | MDS1 and EVI1 complex locus | -0.0269589 |
| EPCAM | epithelial cell adhesion molecule | -0.0268535 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0268072 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0266264 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0263407 |
| FNIP1 | folliculin interacting protein 1 | -0.0262188 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0260282 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0258929 |
| MSI2 | musashi RNA-binding protein 2 | -0.0257908 |
| S100A6 | S100 calcium binding protein A6 | -0.0256438 |
| PDE8A | phosphodiesterase 8A | -0.0255219 |
