| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.1591 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.119511 |
| ENO1 | enolase 1, (alpha) | 0.103751 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0874869 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0754114 |
| TXNIP | thioredoxin interacting protein | 0.0642305 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0626704 |
| ZNF638 | zinc finger protein 638 | 0.0601839 |
| H1-0 | H1.0 linker histone | 0.0576707 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0551397 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0550441 |
| MKI67 | marker of proliferation Ki-67 | 0.0534589 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0528531 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0525475 |
| RRM2 | ribonucleotide reductase M2 | 0.0521427 |
| SDC4 | syndecan 4 | 0.0516939 |
| HLA-A | major histocompatibility complex, class I, A | 0.0513965 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0510053 |
| TMF1 | TATA element modulatory factor 1 | 0.0503806 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0495948 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0479171 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0478143 |
| RPL3 | ribosomal protein L3 | 0.0474329 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0471598 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0459151 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0440445 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0438468 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0432975 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.042967 |
| SEPTIN9 | septin 9 | 0.041348 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0412551 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0411808 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0404509 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0403546 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0401855 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0401214 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0392169 |
| FLNB | filamin B, beta | 0.0389566 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.038948 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0386085 |
| FLNA | filamin A, alpha | 0.0384653 |
| PARD3 | par-3 family cell polarity regulator | 0.0379584 |
| KRT19 | keratin 19, type I | 0.0378868 |
| RNF213 | ring finger protein 213 | 0.0376942 |
| TPM3 | tropomyosin 3 | 0.037222 |
| DSPP | dentin sialophosphoprotein | 0.0365292 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0361804 |
| MIDN | midnolin | 0.0358013 |
| MT2A | metallothionein 2A | 0.0353904 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0349284 |
| MCL1 | myeloid cell leukemia 1 | 0.0348507 |
| PCM1 | pericentriolar material 1 | 0.0346581 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0345863 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0345749 |
| WASF2 | WAS protein family, member 2 | 0.0344871 |
| HLA-B | major histocompatibility complex, class I, B | 0.0342763 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.0339392 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0337367 |
| PFKP | phosphofructokinase, platelet | 0.0335881 |
| SETD5 | SET domain containing 5 | 0.0334038 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.032952 |
| PLEC | plectin | 0.0326699 |
| GANAB | glucosidase, alpha; neutral AB | 0.031553 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0315508 |
| SFTPA2 | surfactant protein A2 | 0.0313747 |
| PTK2 | protein tyrosine kinase 2 | 0.031357 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0312466 |
| SNX9 | sorting nexin 9 | 0.0311284 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0305868 |
| PCBP2 | poly(rC) binding protein 2 | 0.0305547 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0302503 |
| FAM117B | family with sequence similarity 117, member B | 0.0299971 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0298012 |
| EPN2 | epsin 2 | 0.0297028 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0296591 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0295871 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0294797 |
| ASPH | aspartate beta-hydroxylase | 0.0294412 |
| BRD4 | bromodomain containing 4 | 0.0293178 |
| CD9 | CD9 molecule | 0.028972 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0286937 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0285751 |
| CTBP2 | C-terminal binding protein 2 | 0.0281072 |
| APP | amyloid beta (A4) precursor protein | 0.0279454 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0276011 |
| LAMA5 | laminin, alpha 5 | 0.02759 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0274091 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0271308 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0271217 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0269412 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0267467 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0266145 |
| RNF24 | ring finger protein 24 | 0.0261146 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0260453 |
| FNIP1 | folliculin interacting protein 1 | 0.0257996 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0257076 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0256966 |
| TMEM14B | transmembrane protein 14B | 0.0256277 |
| DIAPH3 | diaphanous-related formin 3 | 0.0256154 |
| RPL28 | ribosomal protein L28 | 0.0254754 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.211382 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.183531 |
| TXNRD1 | thioredoxin reductase 1 | -0.101183 |
| TMSB10 | thymosin beta 10 | -0.0890472 |
| VCL | vinculin | -0.0813321 |
| RPL35A | ribosomal protein L35a | -0.0786921 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0710324 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0654622 |
| RPLP1 | ribosomal protein, large, P1 | -0.0625461 |
| RPL4 | ribosomal protein L4 | -0.062376 |
| FHIT | fragile histidine triad | -0.0543098 |
| RPS24 | ribosomal protein S24 | -0.0467623 |
| GPHN | gephyrin | -0.0444937 |
| INTS6 | integrator complex subunit 6 | -0.0442114 |
| RPL34 | ribosomal protein L34 | -0.0436667 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0434318 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0429192 |
| CANX | calnexin | -0.0428168 |
| RPL31 | ribosomal protein L31 | -0.042743 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0417592 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0415925 |
| HDLBP | high density lipoprotein binding protein | -0.0411761 |
| RPL23 | ribosomal protein L23 | -0.0405623 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0405041 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0401822 |
| SERINC5 | serine incorporator 5 | -0.0388208 |
| CLTC | clathrin, heavy chain (Hc) | -0.0385668 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0381646 |
| RPS5 | ribosomal protein S5 | -0.0376542 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.037316 |
| TENM3 | teneurin transmembrane protein 3 | -0.0371522 |
| CCND1 | cyclin D1 | -0.0368607 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0352166 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0350889 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0347903 |
| RPL5 | ribosomal protein L5 | -0.0347594 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0343409 |
| TKT | transketolase | -0.032979 |
| RPLP0 | ribosomal protein, large, P0 | -0.0329663 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0328515 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0328403 |
| SON | SON DNA binding protein | -0.0324731 |
| HMGB1 | high mobility group box 1 | -0.0318221 |
| NPR2 | natriuretic peptide receptor 2 | -0.0317521 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0313824 |
| RACK1 | receptor for activated C kinase 1 | -0.0311444 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0305373 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0304832 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0302581 |
| RBM39 | RNA binding motif protein 39 | -0.030225 |
| RRBP1 | ribosome binding protein 1 | -0.0301743 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0301712 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0301651 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0301113 |
| LDHA | lactate dehydrogenase A | -0.0293577 |
| SRP72 | signal recognition particle 72kDa | -0.0286455 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.02863 |
| RPL6 | ribosomal protein L6 | -0.028385 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0283247 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.028215 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0281588 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0276481 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0274285 |
| SCFD1 | sec1 family domain containing 1 | -0.0271323 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0271162 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0270969 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0268379 |
| FTL | ferritin, light polypeptide | -0.0267744 |
| NFIA | nuclear factor I/A | -0.0267701 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0264501 |
| TFRC | transferrin receptor | -0.0264196 |
| LRRC23 | leucine rich repeat containing 23 | -0.0263675 |
| MORF4L2 | mortality factor 4 like 2 | -0.0263369 |
| RPS27A | ribosomal protein S27a | -0.0262669 |
| RPL7 | ribosomal protein L7 | -0.0260198 |
| TJP1 | tight junction protein 1 | -0.0257868 |
| SEC24D | SEC24 family member D | -0.0256168 |
| OLA1 | Obg-like ATPase 1 | -0.0254992 |
| RPL26 | ribosomal protein L26 | -0.02522 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0251502 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.025084 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0250449 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0248717 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0246309 |
| SSR1 | signal sequence receptor, alpha | -0.0245913 |
| RPL19 | ribosomal protein L19 | -0.0244425 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0243246 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.024063 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0240513 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0239312 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0238116 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0236799 |
| ARF1 | ADP-ribosylation factor 1 | -0.0236374 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.023451 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.0234277 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0234029 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0233451 |
| RPS8 | ribosomal protein S8 | -0.0232628 |
| CDK12 | cyclin-dependent kinase 12 | -0.023052 |
| CCDC138 | coiled-coil domain containing 138 | -0.0230429 |
