| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.139688 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.116329 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.100834 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0840999 |
| RAD51B | RAD51 paralog B | 0.082667 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0807272 |
| LAMB3 | laminin, beta 3 | 0.0789666 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.075883 |
| NDRG1 | N-myc downstream regulated 1 | 0.0676011 |
| CD44 | CD44 molecule (Indian blood group) | 0.065906 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0652865 |
| ASPH | aspartate beta-hydroxylase | 0.064233 |
| RUNX1 | runt-related transcription factor 1 | 0.0599802 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.058857 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0585381 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0582348 |
| ANXA2 | annexin A2 | 0.0570536 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0568578 |
| EGFR | epidermal growth factor receptor | 0.0564882 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0553119 |
| TMSB10 | thymosin beta 10 | 0.0539135 |
| HMGA2 | high mobility group AT-hook 2 | 0.0526396 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0506806 |
| ATXN1 | ataxin 1 | 0.0493076 |
| LAMA4 | laminin, alpha 4 | 0.0487003 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0477119 |
| FLNB | filamin B, beta | 0.0461641 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0447643 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0447476 |
| TPM4 | tropomyosin 4 | 0.0446208 |
| SQSTM1 | sequestosome 1 | 0.044525 |
| SMAD3 | SMAD family member 3 | 0.0444508 |
| HMGA1 | high mobility group AT-hook 1 | 0.0436321 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0427285 |
| RPL35A | ribosomal protein L35a | 0.0423238 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0420607 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0411285 |
| RPS8 | ribosomal protein S8 | 0.0410646 |
| MYO1E | myosin IE | 0.0403992 |
| MT2A | metallothionein 2A | 0.0403966 |
| ZFHX3 | zinc finger homeobox 3 | 0.0397193 |
| FHIT | fragile histidine triad | 0.0395147 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0386039 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0381775 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0381109 |
| INTS6 | integrator complex subunit 6 | 0.037749 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0376168 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0376036 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0373724 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0368577 |
| ACTN4 | actinin, alpha 4 | 0.0368443 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0367277 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0361851 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0361463 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0354087 |
| PTMA | prothymosin, alpha | 0.0352483 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0344551 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0334567 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0330038 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0329897 |
| SEPTIN9 | septin 9 | 0.0328408 |
| LAMC2 | laminin, gamma 2 | 0.0321625 |
| RPL37A | ribosomal protein L37a | 0.0318513 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0318496 |
| FLNA | filamin A, alpha | 0.031171 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.03117 |
| EGR1 | early growth response 1 | 0.0310878 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0305928 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0290977 |
| STC2 | stanniocalcin 2 | 0.0286933 |
| ZNF638 | zinc finger protein 638 | 0.028258 |
| SVIL | supervillin | 0.0280841 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0277729 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0274815 |
| CTBP2 | C-terminal binding protein 2 | 0.0273732 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.027163 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0269971 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0267486 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0267116 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0267068 |
| PAX8 | paired box 8 | 0.0265227 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0264956 |
| WWOX | WW domain containing oxidoreductase | 0.0264836 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0264334 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0263984 |
| RPS6 | ribosomal protein S6 | 0.0263441 |
| EHBP1 | EH domain binding protein 1 | 0.0262958 |
| PATJ | PATJ crumbs cell polarity complex component | 0.026289 |
| ITGA6 | integrin, alpha 6 | 0.0262809 |
| RPL28 | ribosomal protein L28 | 0.0262546 |
| ANXA1 | annexin A1 | 0.0261864 |
| CMIP | c-Maf inducing protein | 0.0260912 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0259298 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0259262 |
| H1-0 | H1.0 linker histone | 0.0258897 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0257701 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0256809 |
| NABP1 | nucleic acid binding protein 1 | 0.0248111 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0247561 |
| DENND1A | DENN/MADD domain containing 1A | 0.0246513 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.16282 |
| MATR3 | matrin 3 | -0.0617738 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0594277 |
| GOLGA4 | golgin A4 | -0.0561105 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0517184 |
| MKI67 | marker of proliferation Ki-67 | -0.0500323 |
| B2M | beta-2-microglobulin | -0.0442784 |
| NCKAP1 | NCK-associated protein 1 | -0.0411315 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.038903 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0385782 |
| DSG2 | desmoglein 2 | -0.0385416 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0366253 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0354377 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0352767 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0350604 |
| RNF145 | ring finger protein 145 | -0.0326664 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0324703 |
| APP | amyloid beta (A4) precursor protein | -0.0322976 |
| OGA | O-GlcNAcase | -0.0322691 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.031195 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0306524 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0302716 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0294083 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0293746 |
| ZNF292 | zinc finger protein 292 | -0.0292817 |
| RPL19 | ribosomal protein L19 | -0.0290115 |
| UBQLN1 | ubiquilin 1 | -0.0288437 |
| RBM39 | RNA binding motif protein 39 | -0.0286622 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0284383 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0273584 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0272422 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0272031 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0271669 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0269714 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0266088 |
| PDS5B | PDS5 cohesin associated factor B | -0.0263946 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0261252 |
| XPO1 | exportin 1 | -0.0259971 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0258508 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0257476 |
| CLINT1 | clathrin interactor 1 | -0.0253702 |
| ZNF148 | zinc finger protein 148 | -0.0247886 |
| RPL32 | ribosomal protein L32 | -0.0245298 |
| GMPS | guanine monphosphate synthase | -0.0242247 |
| CLTC | clathrin, heavy chain (Hc) | -0.0241585 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0241056 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0240156 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.023893 |
| FAM168B | family with sequence similarity 168, member B | -0.0236685 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0235633 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0235177 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0234334 |
| AFDN | afadin, adherens junction formation factor | -0.023402 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0232707 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0232327 |
| USP3 | ubiquitin specific peptidase 3 | -0.0231192 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0229943 |
| H1-4 | H1.4 linker histone, cluster member | -0.0227711 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0225181 |
| TMSB4X | thymosin beta 4, X-linked | -0.0224802 |
| FTL | ferritin, light polypeptide | -0.0219747 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.021939 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0218952 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0218451 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0217278 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0216621 |
| HLTF | helicase-like transcription factor | -0.0216463 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0210974 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0210701 |
| TLK1 | tousled-like kinase 1 | -0.0208264 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0208113 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0206244 |
| ITGB8 | integrin, beta 8 | -0.0206231 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.02061 |
| SETD2 | SET domain containing 2 | -0.0205956 |
| TCERG1 | transcription elongation regulator 1 | -0.0205444 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.0204337 |
| GTF2I | general transcription factor IIi | -0.0203841 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0203339 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0202242 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0200577 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0200404 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0199993 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.0198693 |
| IPO7 | importin 7 | -0.0198506 |
| RPL3 | ribosomal protein L3 | -0.0198264 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.019429 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0193913 |
| CCNL1 | cyclin L1 | -0.0192408 |
| TFG | TRK-fused gene | -0.0192318 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0190047 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0189557 |
| ATP11B | ATPase, class VI, type 11B | -0.0189274 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0185413 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0183781 |
| CCNT2 | cyclin T2 | -0.0183356 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0181937 |
| RYK | receptor-like tyrosine kinase | -0.0181325 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0181008 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0180936 |
