| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.164009 |
| MT2A | metallothionein 2A | 0.140391 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.13315 |
| SMAD3 | SMAD family member 3 | 0.117052 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0901257 |
| FAM13A | family with sequence similarity 13, member A | 0.0853371 |
| CDCP1 | CUB domain containing protein 1 | 0.0837347 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0824313 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0765832 |
| RUNX1 | runt-related transcription factor 1 | 0.0761325 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0753258 |
| AXL | AXL receptor tyrosine kinase | 0.0691656 |
| MYO10 | myosin X | 0.0690438 |
| HMGA2 | high mobility group AT-hook 2 | 0.0686098 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0664275 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0653869 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0636733 |
| SYAP1 | synapse associated protein 1 | 0.0625995 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0619907 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0602203 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0600361 |
| PTK2 | protein tyrosine kinase 2 | 0.0591011 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0583165 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0579945 |
| RAI14 | retinoic acid induced 14 | 0.0576834 |
| VEGFC | vascular endothelial growth factor C | 0.0549952 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0544014 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0542282 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0506205 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0501407 |
| FLNB | filamin B, beta | 0.0494284 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0489904 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0484349 |
| DNMBP | dynamin binding protein | 0.0483085 |
| SEPTIN9 | septin 9 | 0.0482466 |
| RPS6 | ribosomal protein S6 | 0.0477652 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.04653 |
| RNF24 | ring finger protein 24 | 0.0454872 |
| SYNJ2 | synaptojanin 2 | 0.0443495 |
| ACTG1 | actin gamma 1 | 0.0441672 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0431673 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0429177 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0419034 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0416402 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0416027 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0413918 |
| ZNF638 | zinc finger protein 638 | 0.0411185 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0410591 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0408079 |
| TENM2 | teneurin transmembrane protein 2 | 0.0405835 |
| RPS8 | ribosomal protein S8 | 0.0403664 |
| NF1 | neurofibromin 1 | 0.0400766 |
| NAV1 | neuron navigator 1 | 0.0393876 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0392712 |
| MT1E | metallothionein 1E | 0.0386838 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.038672 |
| CALU | calumenin | 0.0379027 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0376957 |
| GRAMD1B | GRAM domain containing 1B | 0.0375961 |
| IL1B | interleukin 1, beta | 0.0375577 |
| MYO9B | myosin IXB | 0.0374812 |
| CCND1 | cyclin D1 | 0.0373239 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0366753 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0365525 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0362339 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0353686 |
| MLPH | melanophilin | 0.0351123 |
| BPTF | bromodomain PHD finger transcription factor | 0.0347896 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0346983 |
| YEATS2 | YEATS domain containing 2 | 0.034065 |
| LOXL2 | lysyl oxidase-like 2 | 0.0338381 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0336865 |
| KIF5B | kinesin family member 5B | 0.0335156 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0331108 |
| TGM2 | transglutaminase 2 | 0.0331108 |
| ATP13A3 | ATPase type 13A3 | 0.0329517 |
| ETV6 | ets variant 6 | 0.0329093 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0327693 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0321907 |
| STC1 | stanniocalcin 1 | 0.0321748 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0320447 |
| CEP192 | centrosomal protein 192kDa | 0.032025 |
| RBM25 | RNA binding motif protein 25 | 0.0313608 |
| YBX3 | Y box binding protein 3 | 0.0313411 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0308511 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0308021 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.030779 |
| G0S2 | G0/G1 switch 2 | 0.0305126 |
| NAV2 | neuron navigator 2 | 0.0305093 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.030504 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0305015 |
| RPL37 | ribosomal protein L37 | 0.0304063 |
| RPL11 | ribosomal protein L11 | 0.0303402 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0302646 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0301568 |
| ITGB5 | integrin, beta 5 | 0.0300524 |
| RPL12 | ribosomal protein L12 | 0.030009 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0299972 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0299637 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0299222 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.21529 |
| CDH13 | cadherin 13 | -0.206182 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.188036 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.162892 |
| FN1 | fibronectin 1 | -0.153783 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.131656 |
| VCL | vinculin | -0.110544 |
| TMSB10 | thymosin beta 10 | -0.100293 |
| ASPH | aspartate beta-hydroxylase | -0.0997104 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.082115 |
| PRELID2 | PRELI domain containing 2 | -0.0771773 |
| CANX | calnexin | -0.0758738 |
| IGF2 | insulin-like growth factor 2 | -0.0641518 |
| AHNAK | AHNAK nucleoprotein | -0.0563862 |
| COL5A1 | collagen, type V, alpha 1 | -0.055779 |
| VIM | vimentin | -0.0468519 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.046224 |
| INTS6 | integrator complex subunit 6 | -0.0440529 |
| FMN1 | formin 1 | -0.0413374 |
| NABP1 | nucleic acid binding protein 1 | -0.0401684 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.039048 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.038392 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.038116 |
| SHISA5 | shisa family member 5 | -0.0376357 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0367503 |
| DIAPH2 | diaphanous-related formin 2 | -0.0366794 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0366694 |
| AFF3 | AF4/FMR2 family, member 3 | -0.036513 |
| PTMA | prothymosin, alpha | -0.0355868 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0355852 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0355757 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0350829 |
| PGK1 | phosphoglycerate kinase 1 | -0.034105 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0338812 |
| TNNC1 | troponin C type 1 (slow) | -0.0328281 |
| CFAP20DC | CFAP20 domain containing | -0.032463 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0317445 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0317132 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0310041 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.030996 |
| PHF3 | PHD finger protein 3 | -0.0300688 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0289569 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0284168 |
| MORF4L2 | mortality factor 4 like 2 | -0.0282313 |
| AEBP2 | AE binding protein 2 | -0.0279993 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0276336 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.027463 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0272912 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0266566 |
| HM13 | histocompatibility (minor) 13 | -0.0264201 |
| IER3 | immediate early response 3 | -0.0262985 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0258275 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0258055 |
| GNAS | GNAS complex locus | -0.0257369 |
| CALR | calreticulin | -0.0252628 |
| LDHA | lactate dehydrogenase A | -0.0251011 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0250977 |
| PKM | pyruvate kinase, muscle | -0.0246143 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0244865 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0243822 |
| EGR1 | early growth response 1 | -0.02404 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0240328 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0239313 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0237373 |
| RRBP1 | ribosome binding protein 1 | -0.023349 |
| IPO9 | importin 9 | -0.0231984 |
| CLIC4 | chloride intracellular channel 4 | -0.0230067 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0227631 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0226417 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0225068 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0224135 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0223288 |
| SH2B3 | SH2B adaptor protein 3 | -0.0219789 |
| TTC23L | tetratricopeptide repeat domain 23-like | -0.0219715 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0216628 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0216487 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0215013 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0212885 |
| DTNA | dystrobrevin, alpha | -0.0211374 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0210675 |
| HDLBP | high density lipoprotein binding protein | -0.0210614 |
| DGKI | diacylglycerol kinase, iota | -0.0205792 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0204073 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.020356 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0203471 |
| STXBP1 | syntaxin binding protein 1 | -0.0198268 |
| TMEM263 | transmembrane protein 263 | -0.0197267 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0195711 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.019439 |
| PCNX4 | pecanex 4 | -0.019337 |
| PLS3 | plastin 3 | -0.0187389 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0184942 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0184739 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0183162 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0183143 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0182996 |
| SNX14 | sorting nexin 14 | -0.0180131 |
| S100A10 | S100 calcium binding protein A10 | -0.0179114 |
| RPS24 | ribosomal protein S24 | -0.0176929 |
| PLEC | plectin | -0.0175337 |
