| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.250632 |
| CDH13 | cadherin 13 | 0.198493 |
| COL1A1 | collagen, type I, alpha 1 | 0.0979545 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0974063 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0922081 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0869477 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0785355 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0780831 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0717726 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0650362 |
| COL5A1 | collagen, type V, alpha 1 | 0.0636627 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0616828 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0603291 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0580915 |
| ACTG1 | actin gamma 1 | 0.057262 |
| NDRG1 | N-myc downstream regulated 1 | 0.0566922 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0557622 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0554199 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0548242 |
| FBN1 | fibrillin 1 | 0.0519416 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0507392 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0507186 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0491409 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0482218 |
| CALU | calumenin | 0.0476457 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0475937 |
| NAV2 | neuron navigator 2 | 0.0463425 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.046298 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0458559 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0453195 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0453065 |
| CADM1 | cell adhesion molecule 1 | 0.0426128 |
| NAV1 | neuron navigator 1 | 0.0425823 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0418757 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0408289 |
| PDE10A | phosphodiesterase 10A | 0.0400667 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.039221 |
| APP | amyloid beta (A4) precursor protein | 0.0391946 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0389778 |
| PTK2 | protein tyrosine kinase 2 | 0.0389575 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0378783 |
| FMNL2 | formin-like 2 | 0.0376709 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.03728 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0365014 |
| TPM4 | tropomyosin 4 | 0.0349277 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0345058 |
| PLEC | plectin | 0.0343506 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0339833 |
| LOX | lysyl oxidase | 0.0337646 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0337566 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0335747 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0329669 |
| RUNX1 | runt-related transcription factor 1 | 0.0320125 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0311589 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0311234 |
| VCL | vinculin | 0.0310935 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0309482 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0304235 |
| RPL28 | ribosomal protein L28 | 0.0298892 |
| ATXN1 | ataxin 1 | 0.0292221 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0289728 |
| CDK13 | cyclin-dependent kinase 13 | 0.0288901 |
| CCNY | cyclin Y | 0.0288178 |
| FNIP1 | folliculin interacting protein 1 | 0.0286669 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0286547 |
| SMYD3 | SET and MYND domain containing 3 | 0.0286436 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0285689 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0285515 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0284586 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0284342 |
| CALD1 | caldesmon 1 | 0.0282726 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0282574 |
| CMIP | c-Maf inducing protein | 0.0281196 |
| GANAB | glucosidase, alpha; neutral AB | 0.0280604 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0278068 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0276252 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0275427 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0272356 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0272144 |
| ENO1 | enolase 1, (alpha) | 0.0272073 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0270708 |
| PRELID2 | PRELI domain containing 2 | 0.0269268 |
| EGFR | epidermal growth factor receptor | 0.0267216 |
| SIK3 | SIK family kinase 3 | 0.0264056 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0261091 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0260302 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0260283 |
| GLIS3 | GLIS family zinc finger 3 | 0.0258336 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0256764 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0254339 |
| PARD3 | par-3 family cell polarity regulator | 0.0252088 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0251704 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.024977 |
| CUX1 | cut-like homeobox 1 | 0.0249387 |
| RPS6 | ribosomal protein S6 | 0.0248361 |
| JUN | jun proto-oncogene | 0.0246519 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0243499 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0241363 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0240545 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0239044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.077437 |
| CD44 | CD44 molecule (Indian blood group) | -0.0746201 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0737473 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0630399 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0585013 |
| MT2A | metallothionein 2A | -0.0581173 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.056086 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0474267 |
| IL6ST | interleukin 6 signal transducer | -0.0462149 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0433634 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0413401 |
| ARRDC3 | arrestin domain containing 3 | -0.038683 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0365987 |
| POSTN | periostin, osteoblast specific factor | -0.0353642 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0341318 |
| PTMA | prothymosin, alpha | -0.0335796 |
| TMSB10 | thymosin beta 10 | -0.031715 |
| B2M | beta-2-microglobulin | -0.0313451 |
| PKM | pyruvate kinase, muscle | -0.031299 |
| STC1 | stanniocalcin 1 | -0.03001 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0291321 |
| LDHA | lactate dehydrogenase A | -0.0289614 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.028331 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0282009 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0277502 |
| VCAN | versican | -0.0272214 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0267971 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0253715 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0247728 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0246355 |
| FTL | ferritin, light polypeptide | -0.0240269 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0227947 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0226267 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0223897 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0213817 |
| HAS2 | hyaluronan synthase 2 | -0.0212765 |
| SMAD3 | SMAD family member 3 | -0.0211019 |
| MX2 | MX dynamin-like GTPase 2 | -0.0208195 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0193379 |
| RPL7 | ribosomal protein L7 | -0.0190413 |
| VEGFA | vascular endothelial growth factor A | -0.0187989 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0186542 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0185564 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0184769 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0184473 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0184118 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0178598 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0178148 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0175287 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0172353 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0171895 |
| RPS2 | ribosomal protein S2 | -0.0167224 |
| IFNGR1 | interferon gamma receptor 1 | -0.0161286 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0161163 |
| FBXO32 | F-box protein 32 | -0.0158658 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0157463 |
| TMSB4X | thymosin beta 4, X-linked | -0.0156974 |
| H1-4 | H1.4 linker histone, cluster member | -0.0152913 |
| SERINC3 | serine incorporator 3 | -0.0151131 |
| RPL32 | ribosomal protein L32 | -0.0150272 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0149939 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0149016 |
| CENPF | centromere protein F, 350/400kDa | -0.0146738 |
| MT1X | metallothionein 1X | -0.0143038 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0142778 |
| SQLE | squalene epoxidase | -0.0141935 |
| UBC | ubiquitin C | -0.0141792 |
| INHBA | inhibin, beta A | -0.0141494 |
| SRGN | serglycin | -0.0140825 |
| TMEM123 | transmembrane protein 123 | -0.0140272 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0139792 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0138214 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0136833 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0136245 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.0135986 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0131837 |
| WTAP | Wilms tumor 1 associated protein | -0.0131368 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0128524 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0128371 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0127812 |
| CUL4B | cullin 4B | -0.0127102 |
| TUBA1B | tubulin, alpha 1b | -0.0125464 |
| XPO1 | exportin 1 | -0.0125284 |
| CALR | calreticulin | -0.0124807 |
| AHR | aryl hydrocarbon receptor | -0.0124338 |
| MTSS1 | metastasis suppressor 1 | -0.0124095 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0122754 |
| RPL14 | ribosomal protein L14 | -0.0120715 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.011807 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0117822 |
| PDCD5 | programmed cell death 5 | -0.0117649 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.0113913 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0113849 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.0112415 |
| THBS1 | thrombospondin 1 | -0.011121 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0111206 |
| GATA6 | GATA binding protein 6 | -0.0110209 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) | -0.0110208 |
| INSIG2 | insulin induced gene 2 | -0.0109399 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0109117 |
