| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0897303 |
| KRT20 | keratin 20, type I | 0.0849417 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0831488 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0756883 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0726251 |
| LMO7 | LIM domain 7 | 0.0722343 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0683219 |
| FRY | furry homolog (Drosophila) | 0.0664726 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0625344 |
| RPS6 | ribosomal protein S6 | 0.0596355 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0536605 |
| TMC5 | transmembrane channel-like 5 | 0.0526095 |
| EGR1 | early growth response 1 | 0.0499139 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0494963 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0451734 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0450903 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0427043 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0411688 |
| TRIB1 | tribbles pseudokinase 1 | 0.0409637 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0403276 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0395205 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0388876 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0385832 |
| EZR | ezrin | 0.0384115 |
| TJP1 | tight junction protein 1 | 0.0378714 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0377882 |
| SMAD3 | SMAD family member 3 | 0.0365999 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0363244 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0362799 |
| EXPH5 | exophilin 5 | 0.0357511 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.034355 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0326976 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0320702 |
| NEBL | nebulette | 0.0319805 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0315877 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0314495 |
| ATXN1 | ataxin 1 | 0.0311261 |
| VEGFA | vascular endothelial growth factor A | 0.0309635 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0289526 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0284038 |
| INTS6 | integrator complex subunit 6 | 0.028155 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0280885 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0278639 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.027483 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0273489 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0272135 |
| HKDC1 | hexokinase domain containing 1 | 0.0265293 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.026268 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0262221 |
| MCL1 | myeloid cell leukemia 1 | 0.0261421 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0258713 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0257428 |
| RNF213 | ring finger protein 213 | 0.025674 |
| GOLGB1 | golgin B1 | 0.0256682 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0255226 |
| ACTG1 | actin gamma 1 | 0.0253514 |
| FHL2 | four and a half LIM domains 2 | 0.0253023 |
| FBXO11 | F-box protein 11 | 0.025301 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0250679 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0249469 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0241785 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0239991 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0237696 |
| SIK3 | SIK family kinase 3 | 0.0236288 |
| FOXP1 | forkhead box P1 | 0.022792 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0227195 |
| SGMS2 | sphingomyelin synthase 2 | 0.0224766 |
| TLE4 | transducin-like enhancer of split 4 | 0.0213686 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.021032 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0209115 |
| CUX1 | cut-like homeobox 1 | 0.0209028 |
| RPL13A | ribosomal protein L13a | 0.0206324 |
| OCLN | occludin | 0.0205604 |
| JMJD1C | jumonji domain containing 1C | 0.0205016 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0204339 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.020165 |
| EMP1 | epithelial membrane protein 1 | 0.0200143 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0197761 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0196531 |
| ATF3 | activating transcription factor 3 | 0.0193646 |
| TNS1 | tensin 1 | 0.0193 |
| KLK10 | kallikrein-related peptidase 10 | 0.0192496 |
| RPS12 | ribosomal protein S12 | 0.0191257 |
| LCN2 | lipocalin 2 | 0.0189849 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.018963 |
| JUN | jun proto-oncogene | 0.0188528 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0186803 |
| RND3 | Rho family GTPase 3 | 0.0182254 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0178644 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0178221 |
| POF1B | premature ovarian failure, 1B | 0.0177171 |
| NTN4 | netrin 4 | 0.0174715 |
| ADIPOR2 | adiponectin receptor 2 | 0.0173948 |
| CLDN4 | claudin 4 | 0.0173556 |
| LIPH | lipase, member H | 0.017339 |
| B2M | beta-2-microglobulin | 0.0173212 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0172002 |
| CCNYL1 | cyclin Y-like 1 | 0.0171554 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.0169547 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.016946 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.0940671 |
| LYZ | lysozyme | -0.0881056 |
| FTL | ferritin, light polypeptide | -0.0704469 |
| TXNRD1 | thioredoxin reductase 1 | -0.0685509 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0569137 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0557201 |
| LDHA | lactate dehydrogenase A | -0.0504563 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0460865 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0458824 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0441275 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.043947 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0426533 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.039475 |
| MKI67 | marker of proliferation Ki-67 | -0.0390154 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0389903 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0383403 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0372754 |
| NF1 | neurofibromin 1 | -0.0368259 |
| USP3 | ubiquitin specific peptidase 3 | -0.0365297 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0362431 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0361346 |
| PTK2 | protein tyrosine kinase 2 | -0.0359557 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0359468 |
| CENPF | centromere protein F, 350/400kDa | -0.0346175 |
| GOLGA4 | golgin A4 | -0.0342169 |
| COG5 | component of oligomeric golgi complex 5 | -0.0341383 |
| PTMA | prothymosin, alpha | -0.0340745 |
| WWC1 | WW and C2 domain containing 1 | -0.032455 |
| ANLN | anillin, actin binding protein | -0.0319937 |
| RPL19 | ribosomal protein L19 | -0.0319206 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0318756 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0317512 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0316273 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0315159 |
| RPS24 | ribosomal protein S24 | -0.0313533 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0313192 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0309868 |
| OGA | O-GlcNAcase | -0.0304564 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0301262 |
| NBEAL1 | neurobeachin-like 1 | -0.0301225 |
| EPCAM | epithelial cell adhesion molecule | -0.0300972 |
| TMEM123 | transmembrane protein 123 | -0.028884 |
| ABLIM1 | actin binding LIM protein 1 | -0.0288248 |
| CLTC | clathrin, heavy chain (Hc) | -0.0288112 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.028608 |
| TFRC | transferrin receptor | -0.0279201 |
| SQSTM1 | sequestosome 1 | -0.0273901 |
| CD164 | CD164 molecule, sialomucin | -0.0269529 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0265184 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0264327 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0263055 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0261023 |
| RPLP0 | ribosomal protein, large, P0 | -0.0261013 |
| RPL12 | ribosomal protein L12 | -0.0256804 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0256391 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0256331 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0256301 |
| YBX1 | Y box binding protein 1 | -0.0252033 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0251893 |
| XPO1 | exportin 1 | -0.0250563 |
| PYGB | phosphorylase, glycogen; brain | -0.0248001 |
| HMGA1 | high mobility group AT-hook 1 | -0.0245687 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.024451 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0240445 |
| PGK1 | phosphoglycerate kinase 1 | -0.0240229 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0235652 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0234858 |
| PERP | PERP, TP53 apoptosis effector | -0.0232585 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0231055 |
| RPL18 | ribosomal protein L18 | -0.0229728 |
| MMP7 | matrix metallopeptidase 7 | -0.0226087 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0225524 |
| TPI1 | triosephosphate isomerase 1 | -0.0225231 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0222809 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0222772 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0219805 |
| S100A10 | S100 calcium binding protein A10 | -0.0219767 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0219319 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0219153 |
| TPX2 | TPX2, microtubule-associated | -0.0211623 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0211521 |
| CALR | calreticulin | -0.0210161 |
| RPS21 | ribosomal protein S21 | -0.0209734 |
| FAM135A | family with sequence similarity 135, member A | -0.0208272 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0208001 |
| KRT8 | keratin 8, type II | -0.0206354 |
| KIAA0232 | KIAA0232 | -0.0204569 |
| LNX2 | ligand of numb-protein X 2 | -0.0204091 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0203872 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0203206 |
| RBM39 | RNA binding motif protein 39 | -0.0202847 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0201382 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0201226 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0201173 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0200934 |
| NFIA | nuclear factor I/A | -0.0200934 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0200208 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0199418 |
| RAB10 | RAB10, member RAS oncogene family | -0.0198586 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0198353 |