| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.247164 |
| C3 | complement component 3 | 0.139317 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.123514 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.121494 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.116787 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.114333 |
| SVIL | supervillin | 0.0916721 |
| ATXN1 | ataxin 1 | 0.0826549 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0715213 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0652021 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.065124 |
| TNS1 | tensin 1 | 0.0582851 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0565977 |
| GPC6 | glypican 6 | 0.0552994 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0502501 |
| MT2A | metallothionein 2A | 0.0494989 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.049017 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0476563 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0459998 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0450282 |
| KYNU | kynureninase | 0.0449091 |
| NDRG1 | N-myc downstream regulated 1 | 0.0425092 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0411515 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0403297 |
| SMAD3 | SMAD family member 3 | 0.0402212 |
| IGF2 | insulin-like growth factor 2 | 0.0401964 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0400774 |
| RAD51B | RAD51 paralog B | 0.0399956 |
| DTNA | dystrobrevin, alpha | 0.0398354 |
| POTEF | POTE ankyrin domain family, member F | 0.0394418 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0367607 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0367526 |
| FRMD5 | FERM domain containing 5 | 0.0360919 |
| VEGFA | vascular endothelial growth factor A | 0.035092 |
| DST | dystonin | 0.0342091 |
| RPL3 | ribosomal protein L3 | 0.0332009 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0327475 |
| KIAA1217 | KIAA1217 | 0.0327068 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0325203 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0312099 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0308366 |
| FMNL2 | formin-like 2 | 0.0306939 |
| FLNB | filamin B, beta | 0.0306909 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0302672 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0301843 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0295889 |
| FAM13A | family with sequence similarity 13, member A | 0.0295624 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0294747 |
| KIF1B | kinesin family member 1B | 0.0289777 |
| MCL1 | myeloid cell leukemia 1 | 0.0289266 |
| DIAPH1 | diaphanous-related formin 1 | 0.028584 |
| RUNX1 | runt-related transcription factor 1 | 0.0282352 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0275411 |
| GSE1 | Gse1 coiled-coil protein | 0.0269583 |
| STC2 | stanniocalcin 2 | 0.0267814 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0266421 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0266283 |
| FLNA | filamin A, alpha | 0.0262824 |
| MSI2 | musashi RNA-binding protein 2 | 0.0261344 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0258345 |
| SEPTIN9 | septin 9 | 0.0256845 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0254769 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0253459 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0251726 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0250076 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0248925 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0247028 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0245069 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0244322 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0241597 |
| VMP1 | vacuole membrane protein 1 | 0.0240305 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0239719 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.023881 |
| PRELID2 | PRELI domain containing 2 | 0.0236043 |
| FAM107B | family with sequence similarity 107, member B | 0.023288 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0231126 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0230502 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0229826 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0228868 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0227966 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0225724 |
| FAM219A | family with sequence similarity 219, member A | 0.0224606 |
| RASA2 | RAS p21 protein activator 2 | 0.0222548 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0221928 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0221734 |
| RPL27 | ribosomal protein L27 | 0.022154 |
| CCDC88A | coiled-coil domain containing 88A | 0.0218234 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0217938 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.021767 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0217374 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.021674 |
| USP47 | ubiquitin specific peptidase 47 | 0.0216099 |
| BRD2 | bromodomain containing 2 | 0.0214863 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0214786 |
| DENND1A | DENN/MADD domain containing 1A | 0.0211556 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0209483 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0208807 |
| HPCAL1 | hippocalcin-like 1 | 0.020873 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0208646 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0206127 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.230327 |
| GPC3 | glypican 3 | -0.160071 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.105813 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.105804 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0996857 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0941224 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0887725 |
| TRIM26 | tripartite motif containing 26 | -0.0876674 |
| CP | ceruloplasmin (ferroxidase) | -0.0792507 |
| APOA2 | apolipoprotein A-II | -0.0756224 |
| RPS24 | ribosomal protein S24 | -0.0719407 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0714579 |
| A2M | alpha-2-macroglobulin | -0.070516 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0654953 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0628911 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0628207 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0611719 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0582905 |
| RBM39 | RNA binding motif protein 39 | -0.0579654 |
| TMEM123 | transmembrane protein 123 | -0.0564828 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0556639 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0528971 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0505352 |
| FN1 | fibronectin 1 | -0.0488014 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0484669 |
| RPL35A | ribosomal protein L35a | -0.0480463 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0477956 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0474254 |
| RPL34 | ribosomal protein L34 | -0.0471321 |
| NPR2 | natriuretic peptide receptor 2 | -0.0441731 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0427728 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0419739 |
| PTMA | prothymosin, alpha | -0.0416169 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0415565 |
| TMSB10 | thymosin beta 10 | -0.0413706 |
| EHBP1 | EH domain binding protein 1 | -0.0412057 |
| RRBP1 | ribosome binding protein 1 | -0.0401272 |
| APOE | apolipoprotein E | -0.0398823 |
| PTCHD4 | patched domain containing 4 | -0.0394336 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0378351 |
| VCL | vinculin | -0.0378026 |
| NCOA7 | nuclear receptor coactivator 7 | -0.037137 |
| PEG3 | paternally expressed 3 | -0.0365822 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0362551 |
| LYZ | lysozyme | -0.0356295 |
| RPLP0 | ribosomal protein, large, P0 | -0.0355993 |
| FILIP1L | filamin A interacting protein 1-like | -0.0353363 |
| AHSG | alpha-2-HS-glycoprotein | -0.0352169 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0332152 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0330498 |
| RPLP1 | ribosomal protein, large, P1 | -0.0320518 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0320052 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0319045 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.031797 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0316829 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0309398 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0305554 |
| RPS27A | ribosomal protein S27a | -0.0304562 |
| GNAS | GNAS complex locus | -0.0304502 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0300179 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0298303 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0297702 |
| SELENOP | selenoprotein P | -0.0291003 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0290983 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0290779 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0290393 |
| FTL | ferritin, light polypeptide | -0.0286055 |
| IER3 | immediate early response 3 | -0.0285385 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0284985 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0284112 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0283193 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0279302 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0275159 |
| RBM25 | RNA binding motif protein 25 | -0.0272615 |
| HMGA2 | high mobility group AT-hook 2 | -0.027253 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0257091 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0256402 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0253862 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0246504 |
| RPL31 | ribosomal protein L31 | -0.0245506 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0244606 |
| STK17A | serine/threonine kinase 17a | -0.0244191 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0238492 |
| CFB | complement factor B | -0.0237998 |
| RPS5 | ribosomal protein S5 | -0.0237474 |
| GLG1 | golgi glycoprotein 1 | -0.0231015 |
| RPL12 | ribosomal protein L12 | -0.0227731 |
| RIGI | RNA sensor RIG-I | -0.0227714 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0227555 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0222275 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.0221337 |
| TMEM263 | transmembrane protein 263 | -0.0219055 |
| KIF5B | kinesin family member 5B | -0.0218061 |
| RPL4 | ribosomal protein L4 | -0.0217626 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0216188 |
| PEG10 | paternally expressed 10 | -0.0215042 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0214995 |
| ZFHX3 | zinc finger homeobox 3 | -0.0214649 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0211216 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.021072 |
