| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.0655365 |
| MT2A | metallothionein 2A | 0.0636194 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0593421 |
| INTS6 | integrator complex subunit 6 | 0.0551821 |
| POTEF | POTE ankyrin domain family, member F | 0.0515869 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0507963 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0498782 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0410594 |
| TGM2 | transglutaminase 2 | 0.0401462 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0398951 |
| BCL2L1 | BCL2-like 1 | 0.0392278 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0385243 |
| MSN | moesin | 0.0379201 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0363418 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0358903 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0349764 |
| SEPTIN9 | septin 9 | 0.0347415 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0344853 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0341729 |
| RPS12 | ribosomal protein S12 | 0.0341106 |
| PRELID2 | PRELI domain containing 2 | 0.0340579 |
| LAMA5 | laminin, alpha 5 | 0.0329868 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0325775 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0325186 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0321585 |
| RASAL2 | RAS protein activator like 2 | 0.0311666 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0307869 |
| PLAT | plasminogen activator, tissue | 0.0295307 |
| RPS21 | ribosomal protein S21 | 0.0288447 |
| RPS6 | ribosomal protein S6 | 0.0286014 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0284745 |
| PCDH1 | protocadherin 1 | 0.0269114 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0266572 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0261224 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0257817 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0254801 |
| RPL11 | ribosomal protein L11 | 0.0254115 |
| RPLP2 | ribosomal protein, large, P2 | 0.0253429 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0253109 |
| PLXNA2 | plexin A2 | 0.0246047 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0242338 |
| FOXO1 | forkhead box O1 | 0.0235951 |
| CLU | clusterin | 0.0233829 |
| MCL1 | myeloid cell leukemia 1 | 0.0228752 |
| NECTIN1 | nectin cell adhesion molecule 1 | 0.022585 |
| CAPRIN2 | caprin family member 2 | 0.0225573 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0222381 |
| RPL23 | ribosomal protein L23 | 0.0220929 |
| JAG1 | jagged 1 | 0.0219517 |
| RIN2 | Ras and Rab interactor 2 | 0.0219363 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0218531 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0217404 |
| RPS19 | ribosomal protein S19 | 0.021476 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0214086 |
| DUSP4 | dual specificity phosphatase 4 | 0.0213757 |
| LUZP1 | leucine zipper protein 1 | 0.0211484 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0207838 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0206983 |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.0205972 |
| RPL21 | ribosomal protein L21 | 0.0204916 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.020312 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0197587 |
| HMGA2 | high mobility group AT-hook 2 | 0.0196014 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0192217 |
| VCL | vinculin | 0.0191784 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0191217 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0189136 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0188627 |
| NBEA | neurobeachin | 0.0187449 |
| EFNA5 | ephrin-A5 | 0.0187173 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.018585 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0185327 |
| TNS4 | tensin 4 | 0.0184002 |
| RPS23 | ribosomal protein S23 | 0.0182387 |
| CMIP | c-Maf inducing protein | 0.0178512 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.017838 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.017806 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0176311 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0176005 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.017445 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.017425 |
| AMOTL1 | angiomotin like 1 | 0.0172859 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0171313 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0171274 |
| SLK | STE20-like kinase | 0.0167972 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0167059 |
| CD44 | CD44 molecule (Indian blood group) | 0.0165139 |
| NRG1 | neuregulin 1 | 0.0164963 |
| METTL15 | methyltransferase like 15 | 0.0164525 |
| RPL9 | ribosomal protein L9 | 0.016351 |
| RAD51B | RAD51 paralog B | 0.0161988 |
| VMP1 | vacuole membrane protein 1 | 0.0159283 |
| SLTM | SAFB-like, transcription modulator | 0.0159198 |
| RPL35 | ribosomal protein L35 | 0.015883 |
| ATXN7L1 | ataxin 7-like 1 | 0.0158292 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0157404 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.015627 |
| PTK2 | protein tyrosine kinase 2 | 0.0154986 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0154699 |
| PHF14 | PHD finger protein 14 | 0.0154336 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.272964 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.1603 |
| SULF1 | sulfatase 1 | -0.098084 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0865094 |
| MEF2A | myocyte enhancer factor 2A | -0.0829541 |
| PTMA | prothymosin, alpha | -0.0820301 |
| AHNAK | AHNAK nucleoprotein | -0.0787812 |
| PGK1 | phosphoglycerate kinase 1 | -0.0769563 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0702056 |
| RAI14 | retinoic acid induced 14 | -0.0685735 |
| MTSS1 | metastasis suppressor 1 | -0.0633486 |
| LMO7 | LIM domain 7 | -0.0610714 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0604072 |
| HLA-E | major histocompatibility complex, class I, E | -0.0588966 |
| NDRG1 | N-myc downstream regulated 1 | -0.0535731 |
| TMSB4X | thymosin beta 4, X-linked | -0.0527518 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0517535 |
| CANX | calnexin | -0.0506836 |
| SQLE | squalene epoxidase | -0.0506411 |
| EMP1 | epithelial membrane protein 1 | -0.0484942 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0469735 |
| LAMC2 | laminin, gamma 2 | -0.0455131 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.044634 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0440225 |
| STC1 | stanniocalcin 1 | -0.043973 |
| GOLGA4 | golgin A4 | -0.0413673 |
| ANXA2 | annexin A2 | -0.0413357 |
| RBM39 | RNA binding motif protein 39 | -0.0410617 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0407599 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0395352 |
| CALB1 | calbindin 1, 28kDa | -0.039441 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0392724 |
| IGF2 | insulin-like growth factor 2 | -0.0381972 |
| LDHA | lactate dehydrogenase A | -0.038144 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0381241 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0378768 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0363739 |
| CAVIN1 | caveolae associated protein 1 | -0.0363146 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0360419 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0347023 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0342949 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.034264 |
| OGA | O-GlcNAcase | -0.0335354 |
| LMNA | lamin A/C | -0.0321291 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0320054 |
| ANXA1 | annexin A1 | -0.0313999 |
| FLNB | filamin B, beta | -0.0305092 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0304948 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0302837 |
| FN1 | fibronectin 1 | -0.0302528 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0300394 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0299099 |
| CALU | calumenin | -0.0299011 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0294076 |
| S100A10 | S100 calcium binding protein A10 | -0.0291008 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0282604 |
| KRT6A | keratin 6A, type II | -0.0281022 |
| KRT17 | keratin 17, type I | -0.0278851 |
| RRBP1 | ribosome binding protein 1 | -0.0269977 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0266431 |
| ENO1 | enolase 1, (alpha) | -0.0261674 |
| MORF4L2 | mortality factor 4 like 2 | -0.0259713 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0257359 |
| TPM4 | tropomyosin 4 | -0.0256783 |
| DSG2 | desmoglein 2 | -0.0256622 |
| SPAG9 | sperm associated antigen 9 | -0.0255498 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0253467 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0251724 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0249603 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0247173 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0246039 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.024433 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0242159 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0241593 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0240341 |
| XPO1 | exportin 1 | -0.0239539 |
| EZR | ezrin | -0.0237502 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0233707 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0232279 |
| THBD | thrombomodulin | -0.0232237 |
| FBXO11 | F-box protein 11 | -0.0231238 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0230428 |
| HM13 | histocompatibility (minor) 13 | -0.0229686 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0229147 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0228371 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0227814 |
| GNAS | GNAS complex locus | -0.0227145 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0226524 |
| RAI1 | retinoic acid induced 1 | -0.0226 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0223971 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0219598 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0218936 |
| CD99 | CD99 molecule | -0.0216836 |
| RPLP1 | ribosomal protein, large, P1 | -0.0215825 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0214 |
| PODXL | podocalyxin-like | -0.0211922 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0209331 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0208933 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0208845 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0205286 |
