| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.142027 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.139604 |
| NAV2 | neuron navigator 2 | 0.105485 |
| POTEF | POTE ankyrin domain family, member F | 0.101219 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0925805 |
| ERBIN | erbb2 interacting protein | 0.0844877 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0796195 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0781531 |
| MSN | moesin | 0.0760474 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0696792 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0691459 |
| PTK2 | protein tyrosine kinase 2 | 0.0673637 |
| NDRG1 | N-myc downstream regulated 1 | 0.0667092 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0653098 |
| FLNB | filamin B, beta | 0.0616432 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0601394 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0571119 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0527681 |
| FOSL1 | FOS-like antigen 1 | 0.0520121 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0492061 |
| MT2A | metallothionein 2A | 0.0490056 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0487249 |
| SMAD3 | SMAD family member 3 | 0.0486983 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0486483 |
| DTNA | dystrobrevin, alpha | 0.0467196 |
| DST | dystonin | 0.0457547 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0456955 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0451452 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0442211 |
| ASPH | aspartate beta-hydroxylase | 0.043912 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0435859 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0435303 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0426257 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0426037 |
| PODXL | podocalyxin-like | 0.0420654 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0418576 |
| ZNF841 | zinc finger protein 841 | 0.041632 |
| FLNA | filamin A, alpha | 0.0412263 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0409804 |
| DIAPH3 | diaphanous-related formin 3 | 0.0406706 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0401353 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0398284 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.038885 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0388719 |
| EGFR | epidermal growth factor receptor | 0.0382381 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0373897 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0373682 |
| RAD51B | RAD51 paralog B | 0.037081 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0366894 |
| NAV1 | neuron navigator 1 | 0.0366111 |
| SEPTIN9 | septin 9 | 0.0361177 |
| VEGFA | vascular endothelial growth factor A | 0.0355246 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.035369 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0351283 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0338704 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0332738 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0332687 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0328467 |
| MCL1 | myeloid cell leukemia 1 | 0.0327741 |
| ATXN1 | ataxin 1 | 0.0326677 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0316528 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0314414 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0312461 |
| SMYD3 | SET and MYND domain containing 3 | 0.0307406 |
| ACTN1 | actinin, alpha 1 | 0.0305602 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0303881 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0301539 |
| NOTCH2 | notch 2 | 0.0300553 |
| PCBP2 | poly(rC) binding protein 2 | 0.0292101 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0291916 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.028922 |
| INTS6 | integrator complex subunit 6 | 0.0287899 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0286895 |
| MYO10 | myosin X | 0.0286304 |
| RUNX1 | runt-related transcription factor 1 | 0.0285898 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.028469 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0277768 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0274735 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0272614 |
| CALD1 | caldesmon 1 | 0.0270097 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0267173 |
| MT1X | metallothionein 1X | 0.0263529 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0262436 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0261241 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0260969 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0260886 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0259974 |
| COL5A1 | collagen, type V, alpha 1 | 0.0259751 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0257078 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0256321 |
| TLE4 | transducin-like enhancer of split 4 | 0.0254434 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0252666 |
| AXL | AXL receptor tyrosine kinase | 0.0251657 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0249129 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0248104 |
| WWOX | WW domain containing oxidoreductase | 0.0247547 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0242537 |
| ACTG1 | actin gamma 1 | 0.0241192 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0240609 |
| SET | SET nuclear proto-oncogene | 0.0238635 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.285213 |
| HLA-B | major histocompatibility complex, class I, B | -0.134099 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.129773 |
| FTL | ferritin, light polypeptide | -0.124562 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0888459 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0817984 |
| CANX | calnexin | -0.0777728 |
| FN1 | fibronectin 1 | -0.0636342 |
| AHNAK | AHNAK nucleoprotein | -0.0611865 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0602755 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0572641 |
| TMSB4X | thymosin beta 4, X-linked | -0.0554784 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0486994 |
| B2M | beta-2-microglobulin | -0.0484935 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0477107 |
| HLA-C | major histocompatibility complex, class I, C | -0.0472735 |
| TXNRD1 | thioredoxin reductase 1 | -0.0457617 |
| PTMA | prothymosin, alpha | -0.0452199 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0444176 |
| CALR | calreticulin | -0.0434036 |
| TMSB10 | thymosin beta 10 | -0.0429732 |
| IL6ST | interleukin 6 signal transducer | -0.0408524 |
| PGK1 | phosphoglycerate kinase 1 | -0.0403422 |
| TUBB | tubulin, beta class I | -0.0401487 |
| POSTN | periostin, osteoblast specific factor | -0.0400872 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0399901 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0392078 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0389464 |
| TKT | transketolase | -0.0386076 |
| HLA-E | major histocompatibility complex, class I, E | -0.0380488 |
| ENO1 | enolase 1, (alpha) | -0.0362455 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0353413 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0351547 |
| PLIN2 | perilipin 2 | -0.0350544 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0349738 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0347711 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.034451 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0340129 |
| GNAS | GNAS complex locus | -0.0327703 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.032019 |
| OSMR | oncostatin M receptor | -0.0319423 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0317503 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0312386 |
| ANXA2 | annexin A2 | -0.0304027 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0301204 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0296089 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0294691 |
| LDHA | lactate dehydrogenase A | -0.0293176 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0287743 |
| RPS24 | ribosomal protein S24 | -0.0284791 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0283698 |
| CTSD | cathepsin D | -0.0280674 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0277205 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0276038 |
| ARF1 | ADP-ribosylation factor 1 | -0.0274102 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0273344 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0267824 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0266994 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0265177 |
| ATP13A3 | ATPase type 13A3 | -0.0262065 |
| CLTC | clathrin, heavy chain (Hc) | -0.0257438 |
| TMEM263 | transmembrane protein 263 | -0.0254617 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0252887 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0252423 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0251482 |
| CUL4B | cullin 4B | -0.0251425 |
| SDCBP | syndecan binding protein (syntenin) | -0.0250162 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0248874 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0244613 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0240223 |
| LMAN1 | lectin, mannose-binding, 1 | -0.023805 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0232472 |
| S100A6 | S100 calcium binding protein A6 | -0.0232186 |
| CAVIN1 | caveolae associated protein 1 | -0.0231672 |
| MORF4L2 | mortality factor 4 like 2 | -0.0230902 |
| HDLBP | high density lipoprotein binding protein | -0.0229607 |
| UBC | ubiquitin C | -0.0227191 |
| RPL12 | ribosomal protein L12 | -0.0226043 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0223062 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0219131 |
| SSR1 | signal sequence receptor, alpha | -0.0218864 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0218346 |
| VIM | vimentin | -0.0216767 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0216378 |
| S100A10 | S100 calcium binding protein A10 | -0.0214649 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0214634 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0214376 |
| IER3 | immediate early response 3 | -0.0212539 |
| RPL35A | ribosomal protein L35a | -0.0211055 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0209616 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.020586 |
| LOX | lysyl oxidase | -0.0205813 |
| SQSTM1 | sequestosome 1 | -0.020492 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.0203016 |
| COL3A1 | collagen, type III, alpha 1 | -0.0201846 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0201302 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0198239 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0197512 |
| RPL34 | ribosomal protein L34 | -0.0195071 |
| GOLT1B | golgi transport 1B | -0.0192674 |
