| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.142411 |
| EFNA5 | ephrin-A5 | 0.130572 |
| MT2A | metallothionein 2A | 0.129105 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.128041 |
| FTL | ferritin, light polypeptide | 0.0906494 |
| ACTG1 | actin gamma 1 | 0.0801877 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0794328 |
| RUNX1 | runt-related transcription factor 1 | 0.0678823 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0671776 |
| NAV1 | neuron navigator 1 | 0.0649873 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0627336 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.062466 |
| RPS6 | ribosomal protein S6 | 0.0617909 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0604144 |
| ASPH | aspartate beta-hydroxylase | 0.0598874 |
| EGR1 | early growth response 1 | 0.0597029 |
| RPLP1 | ribosomal protein, large, P1 | 0.0503959 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0483811 |
| HDAC9 | histone deacetylase 9 | 0.0482958 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0476763 |
| KIAA1549L | KIAA1549-like | 0.0461037 |
| HMGA2 | high mobility group AT-hook 2 | 0.0459509 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0454203 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0452855 |
| FLNA | filamin A, alpha | 0.0439342 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0430584 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.043031 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0427902 |
| DTNA | dystrobrevin, alpha | 0.042747 |
| PRKCE | protein kinase C, epsilon | 0.0420211 |
| ZNF638 | zinc finger protein 638 | 0.0408862 |
| RPL28 | ribosomal protein L28 | 0.0408538 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0396449 |
| JMJD1C | jumonji domain containing 1C | 0.0391782 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0385294 |
| RPS2 | ribosomal protein S2 | 0.038291 |
| HSPA8 | heat shock 70kDa protein 8 | 0.037221 |
| TLE4 | transducin-like enhancer of split 4 | 0.0369772 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0347516 |
| CALD1 | caldesmon 1 | 0.0343512 |
| RPL27 | ribosomal protein L27 | 0.0342697 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0334129 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.033025 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0313315 |
| NABP1 | nucleic acid binding protein 1 | 0.0311452 |
| SATB2 | SATB homeobox 2 | 0.0309283 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0307645 |
| GPHN | gephyrin | 0.0305948 |
| RPS19 | ribosomal protein S19 | 0.0303969 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0299953 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0299278 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0293649 |
| CD44 | CD44 molecule (Indian blood group) | 0.0292025 |
| MCL1 | myeloid cell leukemia 1 | 0.0291672 |
| MSN | moesin | 0.028743 |
| ATXN1 | ataxin 1 | 0.028727 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0282568 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0277085 |
| CD163L1 | CD163 molecule-like 1 | 0.0270771 |
| USP34 | ubiquitin specific peptidase 34 | 0.0270718 |
| FOXP1 | forkhead box P1 | 0.0268642 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0267667 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0266928 |
| RPL36 | ribosomal protein L36 | 0.0265733 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.026443 |
| GLIS3 | GLIS family zinc finger 3 | 0.0263151 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0261613 |
| CCN2 | cellular communication network factor 2 | 0.0259246 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0252848 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0250997 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0250475 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0249603 |
| LOC112694756 | uncharaterized LOC112694756 | 0.02461 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0245687 |
| CMIP | c-Maf inducing protein | 0.0243769 |
| BRD2 | bromodomain containing 2 | 0.0240166 |
| RPS12 | ribosomal protein S12 | 0.023939 |
| KLHL29 | kelch-like family member 29 | 0.0235572 |
| RPS20 | ribosomal protein S20 | 0.0235223 |
| RNF213 | ring finger protein 213 | 0.023494 |
| KIAA1217 | KIAA1217 | 0.0234443 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0232839 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.023179 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0227234 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0224176 |
| INTS6 | integrator complex subunit 6 | 0.0222767 |
| BPTF | bromodomain PHD finger transcription factor | 0.0221402 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | 0.0221122 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0220992 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0220456 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0218975 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0218841 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0217836 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0216396 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0216369 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0216219 |
| RPL13A | ribosomal protein L13a | 0.0216012 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0215684 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0214638 |
| NCOR2 | nuclear receptor corepressor 2 | 0.021422 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.214606 |
| PTMA | prothymosin, alpha | -0.129589 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.124589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107377 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.106186 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0899605 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0881227 |
| MMP12 | matrix metallopeptidase 12 | -0.0852558 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0828022 |
| UBC | ubiquitin C | -0.070849 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0693801 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0660067 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0653352 |
| TMSB10 | thymosin beta 10 | -0.0632459 |
| SPAG9 | sperm associated antigen 9 | -0.0620405 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0618734 |
| AHNAK | AHNAK nucleoprotein | -0.0611816 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.060884 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0589936 |
| RPS27A | ribosomal protein S27a | -0.0588406 |
| LSAMP | limbic system-associated membrane protein | -0.0582157 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0579918 |
| NUP58 | nucleoporin 58 | -0.0572378 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0553306 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0537073 |
| CANX | calnexin | -0.0522188 |
| RPS24 | ribosomal protein S24 | -0.0511299 |
| ZNF292 | zinc finger protein 292 | -0.0501786 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0498358 |
| FN1 | fibronectin 1 | -0.0497268 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0485792 |
| CD109 | CD109 molecule | -0.0465948 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0455076 |
| RBM39 | RNA binding motif protein 39 | -0.0432061 |
| QKI | QKI, KH domain containing, RNA binding | -0.0429234 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0428238 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0426451 |
| RYBP | RING1 and YY1 binding protein | -0.0415275 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0410553 |
| RLF | rearranged L-myc fusion | -0.0405523 |
| RNF145 | ring finger protein 145 | -0.0399806 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0385463 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0383509 |
| USP3 | ubiquitin specific peptidase 3 | -0.0381875 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0380337 |
| WDR45B | WD repeat domain 45B | -0.0375063 |
| ZNF207 | zinc finger protein 207 | -0.0368987 |
| CDK17 | cyclin-dependent kinase 17 | -0.0366245 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0365135 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0363646 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0360859 |
| OGA | O-GlcNAcase | -0.035573 |
| HELZ | helicase with zinc finger | -0.0354499 |
| NCKAP1 | NCK-associated protein 1 | -0.0347161 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0342533 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0341477 |
| FAM162A | family with sequence similarity 162, member A | -0.0341259 |
| TFG | TRK-fused gene | -0.0341227 |
| PCBP2 | poly(rC) binding protein 2 | -0.034114 |
| ANXA2 | annexin A2 | -0.0338481 |
| TMEM123 | transmembrane protein 123 | -0.0335374 |
| SBF2 | SET binding factor 2 | -0.0331366 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0330973 |
| PGK1 | phosphoglycerate kinase 1 | -0.0329022 |
| PARD3 | par-3 family cell polarity regulator | -0.0327183 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.032649 |
| FNDC3B | fibronectin type III domain containing 3B | -0.032625 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0324663 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0321538 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0315928 |
| APP | amyloid beta (A4) precursor protein | -0.0315118 |
| NOP58 | NOP58 ribonucleoprotein | -0.0311918 |
| SEPTIN7 | septin 7 | -0.0302936 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0301552 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0301127 |
| WDR43 | WD repeat domain 43 | -0.0295959 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0295313 |
| PHIP | pleckstrin homology domain interacting protein | -0.0291591 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0289066 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0286472 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0283752 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280443 |
| GNAS | GNAS complex locus | -0.0280083 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0278854 |
| ECT2 | epithelial cell transforming 2 | -0.0278459 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0277187 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0274316 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0272488 |
| PKM | pyruvate kinase, muscle | -0.0271353 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0269357 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0266636 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0265986 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0265171 |
| MATR3 | matrin 3 | -0.0263855 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0262536 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0260852 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0260193 |
| TMEM263 | transmembrane protein 263 | -0.0260119 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0259946 |
| IER3 | immediate early response 3 | -0.0258495 |
