| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.194244 |
| RPS6 | ribosomal protein S6 | 0.102271 |
| FAT1 | FAT atypical cadherin 1 | 0.0879319 |
| TNS4 | tensin 4 | 0.0797039 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0739195 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0689172 |
| AREG | amphiregulin | 0.0681034 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0661181 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0641488 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0641 |
| RPS2 | ribosomal protein S2 | 0.0612488 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0588342 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0586352 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0572622 |
| VEGFA | vascular endothelial growth factor A | 0.0558568 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0542411 |
| RPS12 | ribosomal protein S12 | 0.0524005 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0515384 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0482681 |
| RPL3 | ribosomal protein L3 | 0.0471132 |
| ABHD2 | abhydrolase domain containing 2 | 0.0423465 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0411491 |
| H1-0 | H1.0 linker histone | 0.0405073 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.040463 |
| MYO1E | myosin IE | 0.0398973 |
| POTEF | POTE ankyrin domain family, member F | 0.039183 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.037092 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0361017 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0359163 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0356902 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.034999 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0335165 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0335032 |
| ENO1 | enolase 1, (alpha) | 0.0334871 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0332389 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0330755 |
| RPS3 | ribosomal protein S3 | 0.0299463 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0295139 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0293719 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.028075 |
| PCBP2 | poly(rC) binding protein 2 | 0.0275882 |
| RPL27 | ribosomal protein L27 | 0.0274421 |
| NDRG1 | N-myc downstream regulated 1 | 0.026863 |
| TXNIP | thioredoxin interacting protein | 0.0263457 |
| BRD2 | bromodomain containing 2 | 0.0258705 |
| TPM4 | tropomyosin 4 | 0.0257109 |
| CADPS | Ca++-dependent secretion activator | 0.0251336 |
| LDHA | lactate dehydrogenase A | 0.0251227 |
| ACTN4 | actinin, alpha 4 | 0.025073 |
| ITGB4 | integrin, beta 4 | 0.0249869 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0249698 |
| PTEN | phosphatase and tensin homolog | 0.0249063 |
| MT2A | metallothionein 2A | 0.0248548 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0247883 |
| RPL21 | ribosomal protein L21 | 0.024559 |
| RNF145 | ring finger protein 145 | 0.0241528 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0237906 |
| RPS26 | ribosomal protein S26 | 0.0236462 |
| RPS8 | ribosomal protein S8 | 0.0234231 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0232654 |
| RPS27 | ribosomal protein S27 | 0.0232366 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0228909 |
| SEPTIN9 | septin 9 | 0.0228359 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0227903 |
| PNN | pinin, desmosome associated protein | 0.0222262 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0221897 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0221394 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0219852 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0215034 |
| PFN1 | profilin 1 | 0.0213967 |
| RPS29 | ribosomal protein S29 | 0.0213142 |
| CUX1 | cut-like homeobox 1 | 0.0209556 |
| RPL11 | ribosomal protein L11 | 0.0209374 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0209057 |
| RPL37 | ribosomal protein L37 | 0.0208924 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0208286 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0207595 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0206403 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0205699 |
| VMP1 | vacuole membrane protein 1 | 0.0203905 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0202901 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0201968 |
| RREB1 | ras responsive element binding protein 1 | 0.0201863 |
| RNF43 | ring finger protein 43 | 0.0200113 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0199485 |
| SLK | STE20-like kinase | 0.0198463 |
| RPL37A | ribosomal protein L37a | 0.0197576 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0195946 |
| MLEC | malectin | 0.0190803 |
| SVIL | supervillin | 0.0190364 |
| CD9 | CD9 molecule | 0.0188594 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0188155 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0187846 |
| PLEC | plectin | 0.0187166 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.018683 |
| HDGF | hepatoma-derived growth factor | 0.0184295 |
| RPL28 | ribosomal protein L28 | 0.0182675 |
| FAM120A | family with sequence similarity 120A | 0.0181831 |
| TMEM45B | transmembrane protein 45B | 0.017987 |
| SET | SET nuclear proto-oncogene | 0.0179755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.272117 |
| TMSB10 | thymosin beta 10 | -0.190032 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.1002 |
| NPSR1 | neuropeptide S receptor 1 | -0.0999511 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0947211 |
| RPL35A | ribosomal protein L35a | -0.0706897 |
| RPS24 | ribosomal protein S24 | -0.0676042 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0660895 |
| RPLP1 | ribosomal protein, large, P1 | -0.0650332 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0620476 |
| RPL34 | ribosomal protein L34 | -0.0607366 |
| EPCAM | epithelial cell adhesion molecule | -0.0502075 |
| S100A6 | S100 calcium binding protein A6 | -0.0466456 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0418473 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0414837 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0410217 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0407574 |
| RRBP1 | ribosome binding protein 1 | -0.0392204 |
| IER3 | immediate early response 3 | -0.0382256 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0374574 |
| ANXA2 | annexin A2 | -0.03642 |
| KRT18 | keratin 18, type I | -0.0354126 |
| AGR2 | anterior gradient 2 | -0.0343873 |
| LMNA | lamin A/C | -0.0323961 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0306182 |
| LAMA4 | laminin, alpha 4 | -0.0305234 |
| ABLIM1 | actin binding LIM protein 1 | -0.0302809 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0284782 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0274894 |
| SERINC5 | serine incorporator 5 | -0.0272456 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0265 |
| TFRC | transferrin receptor | -0.0256557 |
| DSG2 | desmoglein 2 | -0.0254124 |
| RPL4 | ribosomal protein L4 | -0.0253743 |
| CCND1 | cyclin D1 | -0.0253626 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0246815 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0245982 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0245832 |
| AHNAK | AHNAK nucleoprotein | -0.0245339 |
| NFIA | nuclear factor I/A | -0.0242953 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0242195 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0238679 |
| NRN1 | neuritin 1 | -0.0233912 |
| NPR2 | natriuretic peptide receptor 2 | -0.023313 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0225595 |
| FERMT1 | fermitin family member 1 | -0.0222658 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0220806 |
| HMGB1 | high mobility group box 1 | -0.0220597 |
| RPL31 | ribosomal protein L31 | -0.0220355 |
| OGA | O-GlcNAcase | -0.0215292 |
| CDK6 | cyclin-dependent kinase 6 | -0.0211748 |
| TUBB | tubulin, beta class I | -0.0210744 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0210679 |
| RPLP0 | ribosomal protein, large, P0 | -0.0209918 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0207827 |
| RPS5 | ribosomal protein S5 | -0.0207211 |
| ARF1 | ADP-ribosylation factor 1 | -0.0205285 |
| CBX3 | chromobox homolog 3 | -0.0202698 |
| RPL36AL | ribosomal protein L36a-like | -0.0198778 |
| GPHN | gephyrin | -0.0198402 |
| PERP | PERP, TP53 apoptosis effector | -0.0197021 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0195091 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0194887 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.019469 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0192794 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0191452 |
| RPL32 | ribosomal protein L32 | -0.0189001 |
| KPNB1 | karyopherin (importin) beta 1 | -0.018857 |
| H3-3B | H3.3 histone B | -0.0187986 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0187601 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0185619 |
| TMEM123 | transmembrane protein 123 | -0.0184436 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0182469 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0180729 |
| RPL19 | ribosomal protein L19 | -0.0180053 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0179704 |
| MATR3 | matrin 3 | -0.0179548 |
| RPL6 | ribosomal protein L6 | -0.01795 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0179398 |
| RTN3 | reticulon 3 | -0.017837 |
| RBM39 | RNA binding motif protein 39 | -0.0178315 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0177937 |
| TMEM135 | transmembrane protein 135 | -0.0176777 |
| HDAC2 | histone deacetylase 2 | -0.0176715 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0175876 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0175086 |
| CANX | calnexin | -0.0174689 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0174538 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0172255 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0167551 |
| CEP95 | centrosomal protein 95kDa | -0.0167473 |
| RPL5 | ribosomal protein L5 | -0.0164002 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0163793 |
| SSR1 | signal sequence receptor, alpha | -0.0162658 |
| IGFL2 | IGF-like family member 2 | -0.0162482 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0162247 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0161478 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0161153 |
| ENOSF1 | enolase superfamily member 1 | -0.0161071 |
| FHIT | fragile histidine triad | -0.0159114 |
