| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.0922727 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0791145 |
| DSPP | dentin sialophosphoprotein | 0.0711408 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0705855 |
| RPL3 | ribosomal protein L3 | 0.0659008 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0617497 |
| CLDN4 | claudin 4 | 0.0594407 |
| RPS12 | ribosomal protein S12 | 0.0571555 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0523603 |
| EPHA2 | EPH receptor A2 | 0.0499137 |
| AREG | amphiregulin | 0.0496582 |
| RPS2 | ribosomal protein S2 | 0.0465482 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 | 0.0460276 |
| OXSR1 | oxidative stress responsive 1 | 0.0457685 |
| DIAPH1 | diaphanous-related formin 1 | 0.0445016 |
| HLA-A | major histocompatibility complex, class I, A | 0.0441478 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0435446 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0434814 |
| RPS6 | ribosomal protein S6 | 0.0395509 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0387054 |
| PCBP2 | poly(rC) binding protein 2 | 0.0383735 |
| RPL28 | ribosomal protein L28 | 0.0382339 |
| SLTM | SAFB-like, transcription modulator | 0.0365117 |
| MYO5B | myosin VB | 0.0364843 |
| CTBP2 | C-terminal binding protein 2 | 0.0359999 |
| LOC112694756 | uncharaterized LOC112694756 | 0.035979 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0349855 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0349325 |
| MSI2 | musashi RNA-binding protein 2 | 0.0346796 |
| NCOR2 | nuclear receptor corepressor 2 | 0.034168 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0332293 |
| RPL27 | ribosomal protein L27 | 0.0326326 |
| AFDN | afadin, adherens junction formation factor | 0.0322541 |
| ACTG1 | actin gamma 1 | 0.0312911 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0303593 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0301025 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0295403 |
| BRD2 | bromodomain containing 2 | 0.029061 |
| POTEF | POTE ankyrin domain family, member F | 0.0289365 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0282906 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0281108 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0280584 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0279891 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0277807 |
| ANXA11 | annexin A11 | 0.0273933 |
| RREB1 | ras responsive element binding protein 1 | 0.0273153 |
| ZNF638 | zinc finger protein 638 | 0.0272998 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0271257 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0267119 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0263611 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0261841 |
| TXNIP | thioredoxin interacting protein | 0.02604 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.025975 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0257825 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0257697 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0254771 |
| RBM25 | RNA binding motif protein 25 | 0.0254676 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.025344 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0250422 |
| SLK | STE20-like kinase | 0.0248658 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.024612 |
| FLNB | filamin B, beta | 0.0244207 |
| SRPK2 | SRSF protein kinase 2 | 0.0244089 |
| MUC13 | mucin 13, cell surface associated | 0.0243882 |
| TC2N | tandem C2 domains, nuclear | 0.0242178 |
| PLEC | plectin | 0.0239931 |
| RPL21 | ribosomal protein L21 | 0.0239185 |
| RPL37 | ribosomal protein L37 | 0.023795 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.023673 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234196 |
| MT2A | metallothionein 2A | 0.023419 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0233954 |
| SEPTIN9 | septin 9 | 0.023097 |
| FRMD5 | FERM domain containing 5 | 0.0228758 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.0227242 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0224327 |
| SLMAP | sarcolemma associated protein | 0.0223693 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0223647 |
| TJP1 | tight junction protein 1 | 0.0223167 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0218985 |
| HLA-B | major histocompatibility complex, class I, B | 0.0218459 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0218451 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0217463 |
| STRIP2 | striatin interacting protein 2 | 0.0216498 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0216015 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0215361 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0215046 |
| H1-0 | H1.0 linker histone | 0.0214709 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0211896 |
| RBM6 | RNA binding motif protein 6 | 0.0207226 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0206057 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.020582 |
| KRT19 | keratin 19, type I | 0.0205291 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.020414 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0203523 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0201542 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0200316 |
| ITGB4 | integrin, beta 4 | 0.0199434 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0199431 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0198902 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.226091 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.187257 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.166227 |
| RPLP1 | ribosomal protein, large, P1 | -0.123412 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.106178 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0949327 |
| RPS24 | ribosomal protein S24 | -0.0880705 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0873085 |
| RPL34 | ribosomal protein L34 | -0.0829165 |
| RPL35A | ribosomal protein L35a | -0.0807264 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0785133 |
| PTMA | prothymosin, alpha | -0.075314 |
| RPL4 | ribosomal protein L4 | -0.07518 |
| CANX | calnexin | -0.0734566 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0711712 |
| LMO7 | LIM domain 7 | -0.0703109 |
| AGR2 | anterior gradient 2 | -0.0702259 |
| TMSB10 | thymosin beta 10 | -0.0610968 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0609616 |
| RPLP0 | ribosomal protein, large, P0 | -0.0596801 |
| TSPAN8 | tetraspanin 8 | -0.0590974 |
| RPL31 | ribosomal protein L31 | -0.0581942 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0552056 |
| VCL | vinculin | -0.0538984 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0537346 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0535387 |
| RPS8 | ribosomal protein S8 | -0.0519538 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0500938 |
| RPS27A | ribosomal protein S27a | -0.0497348 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0479827 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0479157 |
| RPS25 | ribosomal protein S25 | -0.0460267 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0445184 |
| RPS5 | ribosomal protein S5 | -0.0437505 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0429004 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0416112 |
| HDLBP | high density lipoprotein binding protein | -0.0409306 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0406852 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0397288 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0391783 |
| RPS23 | ribosomal protein S23 | -0.0389013 |
| GOLGB1 | golgin B1 | -0.0386095 |
| RPL9 | ribosomal protein L9 | -0.0382878 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0382326 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0376235 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0373732 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0371918 |
| PLAC8 | placenta-specific 8 | -0.0368275 |
| TXNRD1 | thioredoxin reductase 1 | -0.0367309 |
| CLINT1 | clathrin interactor 1 | -0.0359792 |
| PRELID2 | PRELI domain containing 2 | -0.0355066 |
| RRBP1 | ribosome binding protein 1 | -0.0348372 |
| SERINC5 | serine incorporator 5 | -0.0348074 |
| NPR2 | natriuretic peptide receptor 2 | -0.034739 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0343937 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0335137 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0325496 |
| PKP2 | plakophilin 2 | -0.0323515 |
| CCPG1 | cell cycle progression 1 | -0.0316873 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0316823 |
| RPL32 | ribosomal protein L32 | -0.0316311 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0313534 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0308445 |
| PALLD | palladin, cytoskeletal associated protein | -0.0305385 |
| RPL38 | ribosomal protein L38 | -0.0304132 |
| RPL7 | ribosomal protein L7 | -0.0300074 |
| LDHA | lactate dehydrogenase A | -0.0295264 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.029357 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0292771 |
| SEC24D | SEC24 family member D | -0.0285156 |
| RPS16 | ribosomal protein S16 | -0.0284978 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0284419 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0281656 |
| RPS17 | ribosomal protein S17 | -0.0281061 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0278835 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0268964 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0267379 |
| CLTC | clathrin, heavy chain (Hc) | -0.0263912 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0262144 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0260233 |
| DSG2 | desmoglein 2 | -0.0259361 |
| SSR1 | signal sequence receptor, alpha | -0.0257387 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0253838 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0253665 |
| NPSR1 | neuropeptide S receptor 1 | -0.0252267 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0250553 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0249404 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.024808 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0243893 |
| RAD51B | RAD51 paralog B | -0.0243536 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0242277 |
| EGFR | epidermal growth factor receptor | -0.0242125 |
| STK17A | serine/threonine kinase 17a | -0.0241121 |
| RACK1 | receptor for activated C kinase 1 | -0.0240093 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0239758 |
| MYO1D | myosin ID | -0.0239265 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0236361 |
| AOPEP | aminopeptidase O (putative) | -0.0234167 |
| XPOT | exportin, tRNA | -0.023318 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0230045 |
