| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.133159 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0873158 |
| MT2A | metallothionein 2A | 0.071774 |
| CAPRIN2 | caprin family member 2 | 0.0703055 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0627452 |
| RPS8 | ribosomal protein S8 | 0.0595339 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0574356 |
| ANGPTL4 | angiopoietin-like 4 | 0.0570438 |
| RPL27 | ribosomal protein L27 | 0.0535116 |
| RPS6 | ribosomal protein S6 | 0.0527161 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0503042 |
| TXNRD1 | thioredoxin reductase 1 | 0.0490105 |
| EZR | ezrin | 0.0481678 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0468655 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0450133 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0445213 |
| FMNL2 | formin-like 2 | 0.0444833 |
| RPL28 | ribosomal protein L28 | 0.0429895 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0398224 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0396131 |
| SQSTM1 | sequestosome 1 | 0.0394658 |
| ACTG1 | actin gamma 1 | 0.0382943 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0382607 |
| RPS2 | ribosomal protein S2 | 0.0380237 |
| MT1E | metallothionein 1E | 0.0376023 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0375356 |
| RPL37 | ribosomal protein L37 | 0.0371614 |
| ENO1 | enolase 1, (alpha) | 0.0344858 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0325839 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0319991 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0319715 |
| RPS3 | ribosomal protein S3 | 0.0315165 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0312377 |
| RPS10 | ribosomal protein S10 | 0.0309754 |
| RPL37A | ribosomal protein L37a | 0.0307828 |
| RPS12 | ribosomal protein S12 | 0.0306824 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.030397 |
| RTN4 | reticulon 4 | 0.02991 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0298798 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0291236 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0281986 |
| RPS27 | ribosomal protein S27 | 0.027947 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0274752 |
| APP | amyloid beta (A4) precursor protein | 0.0273769 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.026764 |
| RPS29 | ribosomal protein S29 | 0.0262037 |
| EREG | epiregulin | 0.0259538 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0250052 |
| JMJD1C | jumonji domain containing 1C | 0.0247293 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0244955 |
| YAP1 | Yes-associated protein 1 | 0.0244205 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0237241 |
| HMGA1 | high mobility group AT-hook 1 | 0.0237218 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.023558 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.023514 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0234927 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0234453 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0234061 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0233397 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0232823 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0223781 |
| GOLGB1 | golgin B1 | 0.0221878 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0217794 |
| RPL3 | ribosomal protein L3 | 0.0217168 |
| INTS6 | integrator complex subunit 6 | 0.0208326 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.020624 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0198667 |
| F2R | coagulation factor II (thrombin) receptor | 0.019831 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0196713 |
| EMP1 | epithelial membrane protein 1 | 0.0196411 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0195162 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0194929 |
| BRD2 | bromodomain containing 2 | 0.0194897 |
| YBX3 | Y box binding protein 3 | 0.0192627 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0188373 |
| RPL38 | ribosomal protein L38 | 0.0188174 |
| SVIL | supervillin | 0.0187941 |
| RPLP2 | ribosomal protein, large, P2 | 0.0186622 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0186569 |
| NOCT | nocturnin | 0.0182862 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.018272 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0182215 |
| H1-0 | H1.0 linker histone | 0.018156 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.018011 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0179937 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.017749 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.017563 |
| PNN | pinin, desmosome associated protein | 0.0175047 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0173533 |
| RPL21 | ribosomal protein L21 | 0.0170819 |
| VMP1 | vacuole membrane protein 1 | 0.0170245 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0169211 |
| SRGN | serglycin | 0.016904 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0167137 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0166242 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0165811 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0165548 |
| PLEC | plectin | 0.0163603 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0163193 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0161903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.203996 |
| VIM | vimentin | -0.128398 |
| PTMA | prothymosin, alpha | -0.118954 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.116822 |
| TP63 | tumor protein p63 | -0.106924 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0904528 |
| TMSB4X | thymosin beta 4, X-linked | -0.0899377 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.071825 |
| CD44 | CD44 molecule (Indian blood group) | -0.0668898 |
| CADM2 | cell adhesion molecule 2 | -0.0661128 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0611743 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0551837 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0515468 |
| TNS3 | tensin 3 | -0.0494734 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0488966 |
| CENPF | centromere protein F, 350/400kDa | -0.0453657 |
| EFNA5 | ephrin-A5 | -0.0446644 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0445108 |
| EPHA4 | EPH receptor A4 | -0.0438844 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0432519 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0420588 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0413964 |
| TPI1 | triosephosphate isomerase 1 | -0.0397719 |
| RIGI | RNA sensor RIG-I | -0.0394317 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0379612 |
| EXOC4 | exocyst complex component 4 | -0.0353808 |
| TUBB | tubulin, beta class I | -0.0343425 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0341237 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0337525 |
| VCL | vinculin | -0.0328831 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0321273 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0316264 |
| PLSCR1 | phospholipid scramblase 1 | -0.0306893 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0303608 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0301261 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0300652 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0289508 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0281891 |
| PTK2 | protein tyrosine kinase 2 | -0.0280253 |
| ZNF207 | zinc finger protein 207 | -0.0277021 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0275276 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0274189 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0273746 |
| GNAS | GNAS complex locus | -0.0268708 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0267892 |
| DIAPH3 | diaphanous-related formin 3 | -0.0265394 |
| RAD51B | RAD51 paralog B | -0.0263877 |
| DPH6 | diphthamine biosynthesis 6 | -0.02628 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0259535 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0258664 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0257518 |
| LMNA | lamin A/C | -0.0256296 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0255391 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0250362 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0250233 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0247159 |
| RPS24 | ribosomal protein S24 | -0.0246987 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0246946 |
| EHBP1 | EH domain binding protein 1 | -0.02464 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0246069 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0242516 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0241853 |
| ZNF217 | zinc finger protein 217 | -0.0241755 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0240243 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0239998 |
| SP100 | SP100 nuclear antigen | -0.0239473 |
| RBMX | RNA binding motif protein, X-linked | -0.0238875 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0238092 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0237788 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.023651 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0235894 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0235099 |
| NPR2 | natriuretic peptide receptor 2 | -0.0234225 |
| TUBA1B | tubulin, alpha 1b | -0.0231487 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0231067 |
| RPL35A | ribosomal protein L35a | -0.0225241 |
| MT1X | metallothionein 1X | -0.0223494 |
| SLC38A2 | solute carrier family 38, member 2 | -0.022349 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0220665 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0220385 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0219462 |
| DOCK1 | dedicator of cytokinesis 1 | -0.021844 |
| CBX3 | chromobox homolog 3 | -0.0216197 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0214903 |
| PDE10A | phosphodiesterase 10A | -0.0214048 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.02106 |
| TAOK1 | TAO kinase 1 | -0.0206232 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.0206215 |
| DST | dystonin | -0.0205867 |
| RPL31 | ribosomal protein L31 | -0.0205011 |
| EGFR | epidermal growth factor receptor | -0.0202996 |
| KLF6 | Kruppel-like factor 6 | -0.0202062 |
| KHSRP | KH-type splicing regulatory protein | -0.0200524 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0200432 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0199102 |
| STAG2 | stromal antigen 2 | -0.019835 |
| HDLBP | high density lipoprotein binding protein | -0.0194461 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0194277 |
| PRELID2 | PRELI domain containing 2 | -0.019418 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0192889 |
