| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GLCCI1 | glucocorticoid induced 1 | 0.13905 |
| FAM20C | family with sequence similarity 20, member C | 0.106966 |
| SMAD3 | SMAD family member 3 | 0.0977764 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.092321 |
| NTN4 | netrin 4 | 0.0897723 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0767217 |
| CD44 | CD44 molecule (Indian blood group) | 0.0713143 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0708022 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0678279 |
| TGM2 | transglutaminase 2 | 0.0677026 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0658687 |
| NAV2 | neuron navigator 2 | 0.0572596 |
| KSR1 | kinase suppressor of ras 1 | 0.0558722 |
| STK38L | serine/threonine kinase 38 like | 0.0522951 |
| H1-0 | H1.0 linker histone | 0.0499029 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0498576 |
| VMP1 | vacuole membrane protein 1 | 0.0498092 |
| SEPTIN9 | septin 9 | 0.0489954 |
| FHL2 | four and a half LIM domains 2 | 0.0486298 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0471624 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0467996 |
| SIK3 | SIK family kinase 3 | 0.0466834 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0460712 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0456613 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0448788 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0422659 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0420834 |
| IL1R1 | interleukin 1 receptor, type I | 0.0408987 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0401665 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0400631 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0391746 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0385526 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0377016 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.036537 |
| MT2A | metallothionein 2A | 0.0365172 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0357084 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0351842 |
| HLA-B | major histocompatibility complex, class I, B | 0.0350853 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0349248 |
| NPC1 | Niemann-Pick disease, type C1 | 0.034006 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0328049 |
| PRELID2 | PRELI domain containing 2 | 0.0324515 |
| ECE1 | endothelin converting enzyme 1 | 0.0323397 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0319386 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0318595 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0314872 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0311793 |
| HAS2 | hyaluronan synthase 2 | 0.0310536 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0304754 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0293265 |
| NRP1 | neuropilin 1 | 0.0290277 |
| RBM39 | RNA binding motif protein 39 | 0.028751 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0286379 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0285956 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0281669 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0279258 |
| STX1A | syntaxin 1A (brain) | 0.0278755 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0276925 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0276488 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0274091 |
| ACTN4 | actinin, alpha 4 | 0.0267955 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0266756 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0262748 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.026148 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0260401 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0259839 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0259286 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0258341 |
| ANGPTL4 | angiopoietin-like 4 | 0.0256961 |
| ADD3 | adducin 3 (gamma) | 0.025627 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0254697 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0252444 |
| TOP1 | topoisomerase (DNA) I | 0.0252428 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0250844 |
| LAMA4 | laminin, alpha 4 | 0.0247392 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0247373 |
| TNNC1 | troponin C type 1 (slow) | 0.0247047 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0246 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0244622 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0242683 |
| MYO10 | myosin X | 0.0242644 |
| OGA | O-GlcNAcase | 0.0239191 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0239115 |
| FAM3C | family with sequence similarity 3, member C | 0.0237101 |
| VCL | vinculin | 0.0236904 |
| CORO1C | coronin, actin binding protein, 1C | 0.0235296 |
| EREG | epiregulin | 0.0234568 |
| MSN | moesin | 0.0233499 |
| INTS6 | integrator complex subunit 6 | 0.0232727 |
| TJP1 | tight junction protein 1 | 0.0230379 |
| LUZP1 | leucine zipper protein 1 | 0.0229125 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0226779 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0225348 |
| ANXA10 | annexin A10 | 0.0224433 |
| NPTN | neuroplastin | 0.0224327 |
| HPCAL1 | hippocalcin-like 1 | 0.0224209 |
| ITGB5 | integrin, beta 5 | 0.0222959 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0222517 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0222353 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0220511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.203048 |
| TMSB10 | thymosin beta 10 | -0.155993 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.11654 |
| DPYD | dihydropyrimidine dehydrogenase | -0.109795 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.102947 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.102682 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.100752 |
| MEF2A | myocyte enhancer factor 2A | -0.0958833 |
| USP34 | ubiquitin specific peptidase 34 | -0.0906684 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0827489 |
| CDH13 | cadherin 13 | -0.0822977 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0761152 |
| DST | dystonin | -0.0750935 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0704625 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0678916 |
| NRG1 | neuregulin 1 | -0.0628194 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0624123 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0614403 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.060335 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0601938 |
| PTMA | prothymosin, alpha | -0.0591166 |
| S100A6 | S100 calcium binding protein A6 | -0.0581646 |
| RPLP1 | ribosomal protein, large, P1 | -0.0579421 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0558319 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0557156 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0540336 |
| PKM | pyruvate kinase, muscle | -0.0534808 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0533003 |
| STC1 | stanniocalcin 1 | -0.0506842 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0505889 |
| TMSB4X | thymosin beta 4, X-linked | -0.0505268 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0504413 |
| CA12 | carbonic anhydrase XII | -0.0503503 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0495889 |
| NAV3 | neuron navigator 3 | -0.0492878 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0492563 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0485861 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0484416 |
| NDRG1 | N-myc downstream regulated 1 | -0.0478478 |
| RIOK3 | RIO kinase 3 | -0.0459105 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.045789 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0454083 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0447353 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0442923 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0442727 |
| EGR1 | early growth response 1 | -0.044169 |
| MTSS1 | metastasis suppressor 1 | -0.0431899 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0426948 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0422508 |
| MECOM | MDS1 and EVI1 complex locus | -0.042172 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0409061 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0407746 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0406756 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0405421 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0401232 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0397561 |
| TSPAN5 | tetraspanin 5 | -0.0397386 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0389699 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0383985 |
| OXR1 | oxidation resistance 1 | -0.0383455 |
| PHF21A | PHD finger protein 21A | -0.038128 |
| FAM13A | family with sequence similarity 13, member A | -0.0373789 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0371742 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0370399 |
| FTL | ferritin, light polypeptide | -0.0346433 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0341765 |
| IER3 | immediate early response 3 | -0.033842 |
| FN1 | fibronectin 1 | -0.0338003 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0337619 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0337105 |
| INSIG1 | insulin induced gene 1 | -0.0334863 |
| RPS19 | ribosomal protein S19 | -0.0334607 |
| GPC6 | glypican 6 | -0.0331312 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0328581 |
| RPL34 | ribosomal protein L34 | -0.0327121 |
| POTEF | POTE ankyrin domain family, member F | -0.0326997 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.032558 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.032297 |
| PLIN2 | perilipin 2 | -0.0322859 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0318191 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0317689 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0314606 |
| WWC2 | WW and C2 domain containing 2 | -0.031336 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0312555 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0310275 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.030879 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0305744 |
| NBEAL1 | neurobeachin-like 1 | -0.0304444 |
| MYADM | myeloid-associated differentiation marker | -0.0302773 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0299692 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.029743 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0296667 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0295743 |
| KYNU | kynureninase | -0.0292766 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0290985 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0288236 |
| PCBP2 | poly(rC) binding protein 2 | -0.0287208 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0286692 |
| ASPH | aspartate beta-hydroxylase | -0.0281434 |
| CDCP1 | CUB domain containing protein 1 | -0.027908 |
