| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.237325 |
| GRAMD1B | GRAM domain containing 1B | 0.103439 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0949693 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.092923 |
| RPS12 | ribosomal protein S12 | 0.0706203 |
| RPL23 | ribosomal protein L23 | 0.0593326 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0583511 |
| RPL37A | ribosomal protein L37a | 0.0541843 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.050918 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.04952 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0489699 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.048688 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0478453 |
| RPS3 | ribosomal protein S3 | 0.0466572 |
| ANGPTL4 | angiopoietin-like 4 | 0.0459911 |
| RPL37 | ribosomal protein L37 | 0.0445065 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0437081 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0436456 |
| FMNL2 | formin-like 2 | 0.0432479 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0426051 |
| HLA-B | major histocompatibility complex, class I, B | 0.0414517 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0405207 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0388054 |
| RPS21 | ribosomal protein S21 | 0.0381988 |
| RPS8 | ribosomal protein S8 | 0.0376988 |
| FLNB | filamin B, beta | 0.0376812 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0374563 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0374269 |
| RPL26 | ribosomal protein L26 | 0.0370558 |
| RPS27A | ribosomal protein S27a | 0.0368584 |
| ACTG1 | actin gamma 1 | 0.0354905 |
| EXOC6B | exocyst complex component 6B | 0.0342369 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0329483 |
| FNDC3B | fibronectin type III domain containing 3B | 0.032615 |
| ASPH | aspartate beta-hydroxylase | 0.0324103 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.031696 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0314141 |
| RPS2 | ribosomal protein S2 | 0.0311686 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0307118 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0305075 |
| RPS19 | ribosomal protein S19 | 0.0302132 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.02908 |
| RPL28 | ribosomal protein L28 | 0.0286456 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0285658 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0282454 |
| RPS23 | ribosomal protein S23 | 0.0279718 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0275043 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0272965 |
| RPS29 | ribosomal protein S29 | 0.0271735 |
| RPL9 | ribosomal protein L9 | 0.0269723 |
| STC1 | stanniocalcin 1 | 0.0267773 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0265367 |
| WWOX | WW domain containing oxidoreductase | 0.0265032 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0264222 |
| NDRG1 | N-myc downstream regulated 1 | 0.0263823 |
| HLA-A | major histocompatibility complex, class I, A | 0.026251 |
| RPL36 | ribosomal protein L36 | 0.0259203 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0253018 |
| RPL11 | ribosomal protein L11 | 0.0252931 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0250681 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0249107 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0246362 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0242926 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0240735 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0240098 |
| MT1X | metallothionein 1X | 0.0236227 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.023589 |
| CTBP2 | C-terminal binding protein 2 | 0.0233202 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.0231926 |
| ATXN1 | ataxin 1 | 0.0231914 |
| BMP6 | bone morphogenetic protein 6 | 0.0229198 |
| RPL12 | ribosomal protein L12 | 0.0224533 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0223835 |
| AREG | amphiregulin | 0.0220699 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0219674 |
| RPS6 | ribosomal protein S6 | 0.0216982 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.021523 |
| RPL30 | ribosomal protein L30 | 0.0211949 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0210289 |
| RPS27 | ribosomal protein S27 | 0.0209565 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0208059 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0206699 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0205719 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.0205299 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0205154 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0204784 |
| ZNF638 | zinc finger protein 638 | 0.0204428 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.020078 |
| GPHN | gephyrin | 0.0199097 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0197629 |
| LAMA5 | laminin, alpha 5 | 0.0196148 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0195763 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0195036 |
| RPL18 | ribosomal protein L18 | 0.0194571 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0193698 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0193113 |
| RPS11 | ribosomal protein S11 | 0.0190151 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0189736 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0187997 |
| FHIT | fragile histidine triad | 0.018744 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.23758 |
| VIM | vimentin | -0.218806 |
| FTL | ferritin, light polypeptide | -0.162448 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146443 |
| TXNRD1 | thioredoxin reductase 1 | -0.130316 |
| IGF2 | insulin-like growth factor 2 | -0.120129 |
| PKM | pyruvate kinase, muscle | -0.0869647 |
| FGB | fibrinogen beta chain | -0.0862429 |
| LDHA | lactate dehydrogenase A | -0.0795466 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0764138 |
| POTEF | POTE ankyrin domain family, member F | -0.0759045 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0690818 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0675505 |
| TPM4 | tropomyosin 4 | -0.0609865 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0549072 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0545887 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0532895 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0500398 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0481991 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0481369 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0426903 |
| EGR1 | early growth response 1 | -0.0409526 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0408838 |
| PTMA | prothymosin, alpha | -0.0402305 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0398676 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0392417 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0373483 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0368182 |
| VMP1 | vacuole membrane protein 1 | -0.0365225 |
| NEGR1 | neuronal growth regulator 1 | -0.0363674 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0352217 |
| RPL4 | ribosomal protein L4 | -0.0341501 |
| S100A6 | S100 calcium binding protein A6 | -0.0339598 |
| PLS3 | plastin 3 | -0.0338386 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0336685 |
| TPM3 | tropomyosin 3 | -0.0320076 |
| TPI1 | triosephosphate isomerase 1 | -0.0319367 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0305651 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0299402 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0292521 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0287589 |
| AHR | aryl hydrocarbon receptor | -0.0284288 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0276938 |
| RHOA | ras homolog family member A | -0.0275634 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0273206 |
| SLC38A1 | solute carrier family 38, member 1 | -0.02684 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.02676 |
| SERF2 | small EDRK-rich factor 2 | -0.0263838 |
| MATR3 | matrin 3 | -0.0262325 |
| SERINC3 | serine incorporator 3 | -0.0262077 |
| EFNA5 | ephrin-A5 | -0.0261247 |
| TAGLN2 | transgelin 2 | -0.0259356 |
| FGG | fibrinogen gamma chain | -0.0258753 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.02582 |
| GNAS | GNAS complex locus | -0.0253803 |
| CCNL1 | cyclin L1 | -0.0251227 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0250991 |
| HDAC9 | histone deacetylase 9 | -0.0247201 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.024694 |
| TMEM123 | transmembrane protein 123 | -0.0245211 |
| WDR43 | WD repeat domain 43 | -0.0245161 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0238959 |
| GLG1 | golgi glycoprotein 1 | -0.0236059 |
| LDHB | lactate dehydrogenase B | -0.0235419 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0234551 |
| COPA | coatomer protein complex, subunit alpha | -0.0232334 |
| THBS1 | thrombospondin 1 | -0.0231731 |
| RBM39 | RNA binding motif protein 39 | -0.0231537 |
| LAMB1 | laminin, beta 1 | -0.0231508 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0225257 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0224518 |
| MORF4L2 | mortality factor 4 like 2 | -0.022246 |
| CENPF | centromere protein F, 350/400kDa | -0.0219793 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0219694 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.021902 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0217409 |
| TKT | transketolase | -0.0213266 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0210584 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0209473 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0207101 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0207089 |
| AK1 | adenylate kinase 1 | -0.0206895 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0206802 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0206417 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0206299 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0205555 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.02049 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0204482 |
| ZNF207 | zinc finger protein 207 | -0.020443 |
| ATP5F1A | ATP synthase F1 subunit alpha | -0.0203271 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0200912 |
| PDE8A | phosphodiesterase 8A | -0.0198412 |
| ANXA5 | annexin A5 | -0.0197116 |
| CBX5 | chromobox homolog 5 | -0.0197099 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0196057 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0195916 |
| SPAG9 | sperm associated antigen 9 | -0.0195655 |
| PRR16 | proline rich 16 | -0.0195247 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0194174 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0192349 |
