| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.160654 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.13142 |
| FN1 | fibronectin 1 | 0.12813 |
| EFNA5 | ephrin-A5 | 0.114469 |
| DSCAM | Down syndrome cell adhesion molecule | 0.107879 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0937863 |
| LAMB3 | laminin, beta 3 | 0.0821527 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0763439 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0763159 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0750411 |
| DST | dystonin | 0.0743686 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0708594 |
| MYO1E | myosin IE | 0.0705922 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0657103 |
| ASPH | aspartate beta-hydroxylase | 0.0649314 |
| HMGA2 | high mobility group AT-hook 2 | 0.0647525 |
| LMO7 | LIM domain 7 | 0.0643165 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0628984 |
| SMYD3 | SET and MYND domain containing 3 | 0.0595966 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0594947 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0592469 |
| GPC6 | glypican 6 | 0.057871 |
| VCL | vinculin | 0.057678 |
| MYOF | myoferlin | 0.0557777 |
| FMNL2 | formin-like 2 | 0.0545036 |
| ZNF292 | zinc finger protein 292 | 0.0542766 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0542442 |
| OGA | O-GlcNAcase | 0.0532899 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0527913 |
| EGFR | epidermal growth factor receptor | 0.0514124 |
| FAT1 | FAT atypical cadherin 1 | 0.0500595 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0497922 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0495407 |
| AHNAK | AHNAK nucleoprotein | 0.0490409 |
| ANXA2 | annexin A2 | 0.048924 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0482164 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0478991 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0471179 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0470254 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0466697 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0456326 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0436749 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0436277 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0433526 |
| INHBA | inhibin, beta A | 0.0432349 |
| NABP1 | nucleic acid binding protein 1 | 0.042818 |
| NCKAP1 | NCK-associated protein 1 | 0.0426563 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0425686 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0424679 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0421702 |
| TXNRD1 | thioredoxin reductase 1 | 0.0408367 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0407809 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0404152 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0399298 |
| RTN4 | reticulon 4 | 0.0397556 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0395318 |
| TANK | TRAF family member-associated NFKB activator | 0.0393608 |
| KATNBL1 | katanin p80 subunit B-like 1 | 0.0391348 |
| RBM39 | RNA binding motif protein 39 | 0.0390932 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0387148 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0377584 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0374874 |
| STC1 | stanniocalcin 1 | 0.037009 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.036841 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0367444 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0365085 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0360571 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0360186 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0357106 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0355726 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0355279 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0355065 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0351678 |
| TJP1 | tight junction protein 1 | 0.0351529 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0351521 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0350412 |
| PDE10A | phosphodiesterase 10A | 0.0348995 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0347372 |
| NUMB | numb homolog (Drosophila) | 0.0346451 |
| USP53 | ubiquitin specific peptidase 53 | 0.0346083 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0341137 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0338853 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0336284 |
| FOXP1 | forkhead box P1 | 0.0332811 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0331501 |
| FLNB | filamin B, beta | 0.0331388 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0329701 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0328342 |
| GPHN | gephyrin | 0.0324076 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0323585 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0320544 |
| CUL3 | cullin 3 | 0.0317591 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0315135 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0312864 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0301745 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0298216 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0297884 |
| CDK14 | cyclin-dependent kinase 14 | 0.0297634 |
| APP | amyloid beta (A4) precursor protein | 0.0297084 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0297035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.113714 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0991554 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0931654 |
| LAMC2 | laminin, gamma 2 | -0.081677 |
| MUC16 | mucin 16, cell surface associated | -0.0663494 |
| FTL | ferritin, light polypeptide | -0.0648151 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0647101 |
| KIF13B | kinesin family member 13B | -0.0636947 |
| PTMA | prothymosin, alpha | -0.0630648 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.0578098 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0567993 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0548408 |
| SLMAP | sarcolemma associated protein | -0.0535269 |
| ANKRD36C | ankyrin repeat domain 36C | -0.052952 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0529165 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0523202 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.052023 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0514878 |
| CCNL1 | cyclin L1 | -0.0514339 |
| PGK1 | phosphoglycerate kinase 1 | -0.051358 |
| SP100 | SP100 nuclear antigen | -0.0511728 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0499287 |
| RPS6 | ribosomal protein S6 | -0.0489602 |
| MED13 | mediator complex subunit 13 | -0.048655 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0470772 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0467516 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0459202 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0456645 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0429344 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0421436 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0399995 |
| FOSL2 | FOS-like antigen 2 | -0.0398734 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0395957 |
| CALR | calreticulin | -0.0394961 |
| MYO6 | myosin VI | -0.0390943 |
| TMEM123 | transmembrane protein 123 | -0.0387894 |
| TGFA | transforming growth factor, alpha | -0.0387891 |
| PLSCR1 | phospholipid scramblase 1 | -0.0386826 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0382911 |
| MATR3 | matrin 3 | -0.0376329 |
| RPL19 | ribosomal protein L19 | -0.0374051 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.037228 |
| CLDN7 | claudin 7 | -0.0362595 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0362225 |
| GDF15 | growth differentiation factor 15 | -0.0359855 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -0.0358725 |
| TMEM165 | transmembrane protein 165 | -0.035638 |
| TOP1 | topoisomerase (DNA) I | -0.0353497 |
| ATF6 | activating transcription factor 6 | -0.0352506 |
| PMM2 | phosphomannomutase 2 | -0.0352312 |
| YBX1 | Y box binding protein 1 | -0.0351379 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0348335 |
| RCOR1 | REST corepressor 1 | -0.0345917 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0345439 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0343435 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.034233 |
| RPL23 | ribosomal protein L23 | -0.0340707 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0340432 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0338656 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0335417 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0334799 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0329326 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0327072 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.0326729 |
| RPS11 | ribosomal protein S11 | -0.0326451 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0324612 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0324538 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0323429 |
| GNAS | GNAS complex locus | -0.0322056 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0318305 |
| PHIP | pleckstrin homology domain interacting protein | -0.0318031 |
| ATOSA | atos homolog A | -0.0317664 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0317411 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0310769 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0308812 |
| TPI1 | triosephosphate isomerase 1 | -0.0308452 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.030768 |
| CSTB | cystatin B (stefin B) | -0.0306829 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0306266 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0306011 |
| PREPL | prolyl endopeptidase-like | -0.0304036 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.030345 |
| S100A9 | S100 calcium binding protein A9 | -0.0303374 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0301321 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0299133 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.029896 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0296941 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0296139 |
| GOLGA3 | golgin A3 | -0.0294528 |
| RPL35A | ribosomal protein L35a | -0.0294183 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0291093 |
| ADAR | adenosine deaminase, RNA-specific | -0.028632 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0285198 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0285187 |
| GOLM2 | golgi membrane protein 2 | -0.0284649 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0282606 |
| THOC2 | THO complex 2 | -0.0282258 |
| RBM47 | RNA binding motif protein 47 | -0.0281189 |
| INO80 | INO80 complex subunit | -0.0280669 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | -0.0280052 |
