| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.144734 |
| POTEF | POTE ankyrin domain family, member F | 0.130119 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0896943 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0818162 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0774901 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.070121 |
| MSN | moesin | 0.0692698 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0660812 |
| SDC4 | syndecan 4 | 0.0659238 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0584039 |
| FN1 | fibronectin 1 | 0.0573245 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0559278 |
| PLEC | plectin | 0.0546969 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0524534 |
| ASPH | aspartate beta-hydroxylase | 0.0495714 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0483195 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0480774 |
| CCNL1 | cyclin L1 | 0.0479136 |
| G0S2 | G0/G1 switch 2 | 0.047872 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0472193 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0462151 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0458337 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0454991 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0450112 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0447148 |
| RNF145 | ring finger protein 145 | 0.044078 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0419298 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0419114 |
| MT2A | metallothionein 2A | 0.0412948 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0404229 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0403093 |
| MYO5B | myosin VB | 0.0399027 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0392389 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0385985 |
| HMGA1 | high mobility group AT-hook 1 | 0.0379841 |
| LAMB3 | laminin, beta 3 | 0.0365367 |
| EZR | ezrin | 0.0358158 |
| TXNIP | thioredoxin interacting protein | 0.035542 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0345191 |
| CLDN4 | claudin 4 | 0.034064 |
| PCBP2 | poly(rC) binding protein 2 | 0.0336511 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0331085 |
| VEGFA | vascular endothelial growth factor A | 0.0330528 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0328652 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0326323 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.032494 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0324358 |
| RASA2 | RAS p21 protein activator 2 | 0.0319203 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.031647 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0312067 |
| TPM3 | tropomyosin 3 | 0.030715 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.030251 |
| RPL3 | ribosomal protein L3 | 0.0301575 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0299602 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0296443 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0295562 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0294746 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0292462 |
| FAM3C | family with sequence similarity 3, member C | 0.0290254 |
| RBM25 | RNA binding motif protein 25 | 0.0289605 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0289188 |
| SMAD3 | SMAD family member 3 | 0.028327 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0280192 |
| FLNA | filamin A, alpha | 0.0277767 |
| PTK2 | protein tyrosine kinase 2 | 0.0275677 |
| GPX4 | glutathione peroxidase 4 | 0.0274191 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0268231 |
| YTHDC1 | YTH domain containing 1 | 0.0263815 |
| MYO10 | myosin X | 0.0262899 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0259986 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0259782 |
| DIAPH1 | diaphanous-related formin 1 | 0.0258014 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0257823 |
| RUNX1 | runt-related transcription factor 1 | 0.025541 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0255131 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.025454 |
| ANXA5 | annexin A5 | 0.0249778 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0249581 |
| TFG | TRK-fused gene | 0.0246652 |
| TJP2 | tight junction protein 2 | 0.0245478 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0245063 |
| BRD2 | bromodomain containing 2 | 0.0243203 |
| BCL2L1 | BCL2-like 1 | 0.0242755 |
| JUP | junction plakoglobin | 0.0242469 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0241948 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0240422 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0239425 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0239219 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0239022 |
| SLMAP | sarcolemma associated protein | 0.0238235 |
| DUSP5 | dual specificity phosphatase 5 | 0.0236991 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.023589 |
| RPS2 | ribosomal protein S2 | 0.0234578 |
| ANXA1 | annexin A1 | 0.0233734 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0233049 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0231307 |
| RTN4 | reticulon 4 | 0.0229847 |
| CTSB | cathepsin B | 0.0229326 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0228757 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0227094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.193799 |
| TMSB10 | thymosin beta 10 | -0.165611 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.148344 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.146976 |
| FTL | ferritin, light polypeptide | -0.105347 |
| TMSB4X | thymosin beta 4, X-linked | -0.0980058 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0896527 |
| RPL35A | ribosomal protein L35a | -0.0837567 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0799387 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0793128 |
| CANX | calnexin | -0.0790249 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0779077 |
| FBXO32 | F-box protein 32 | -0.0714428 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0710134 |
| RPL34 | ribosomal protein L34 | -0.0674739 |
| RPLP1 | ribosomal protein, large, P1 | -0.0652959 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0632757 |
| CCND1 | cyclin D1 | -0.0604889 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.059685 |
| TPM4 | tropomyosin 4 | -0.0577926 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.05759 |
| RPS24 | ribosomal protein S24 | -0.0537579 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0535988 |
| VCL | vinculin | -0.0509945 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0481432 |
| EPCAM | epithelial cell adhesion molecule | -0.0475012 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0466999 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0458659 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0440241 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0440106 |
| GNAS | GNAS complex locus | -0.0437443 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0417191 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0413256 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.041091 |
| LMO7 | LIM domain 7 | -0.040669 |
| S100A10 | S100 calcium binding protein A10 | -0.04054 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0399274 |
| FNIP1 | folliculin interacting protein 1 | -0.0398067 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0396173 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0395901 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0394363 |
| FBXO34 | F-box protein 34 | -0.0390593 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0382013 |
| TMEM263 | transmembrane protein 263 | -0.0380721 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0380574 |
| VIM | vimentin | -0.0380105 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0375339 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0375007 |
| RAI14 | retinoic acid induced 14 | -0.0372958 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0367595 |
| RPL31 | ribosomal protein L31 | -0.0362746 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0361513 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0360852 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0360503 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0354321 |
| ARF1 | ADP-ribosylation factor 1 | -0.0353026 |
| CEP350 | centrosomal protein 350kDa | -0.0350026 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0349759 |
| SP100 | SP100 nuclear antigen | -0.0342901 |
| GOLGB1 | golgin B1 | -0.034286 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0337926 |
| RRBP1 | ribosome binding protein 1 | -0.033646 |
| EFNA5 | ephrin-A5 | -0.0333876 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0333274 |
| RPS25 | ribosomal protein S25 | -0.0331619 |
| AHNAK | AHNAK nucleoprotein | -0.0330124 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0329004 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0326873 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0324274 |
| RIGI | RNA sensor RIG-I | -0.0318453 |
| KRT18 | keratin 18, type I | -0.0312344 |
| RNF213 | ring finger protein 213 | -0.031212 |
| PALLD | palladin, cytoskeletal associated protein | -0.0311714 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0308929 |
| TKT | transketolase | -0.0308347 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0307229 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0306645 |
| MCU | mitochondrial calcium uniporter | -0.0301758 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0294899 |
| MYO1E | myosin IE | -0.0293408 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.029328 |
| SQSTM1 | sequestosome 1 | -0.0288632 |
| HDLBP | high density lipoprotein binding protein | -0.0287309 |
| MX2 | MX dynamin-like GTPase 2 | -0.0285247 |
| ZNF217 | zinc finger protein 217 | -0.0281558 |
| S100A6 | S100 calcium binding protein A6 | -0.0280957 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0279248 |
| KRT7 | keratin 7, type II | -0.0278921 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0276494 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0273216 |
| HLA-E | major histocompatibility complex, class I, E | -0.0270123 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0266442 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0265902 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0265422 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0264101 |
| CDK13 | cyclin-dependent kinase 13 | -0.0263511 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0262779 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0262094 |
| RPL32 | ribosomal protein L32 | -0.026147 |
| RPLP0 | ribosomal protein, large, P0 | -0.0261216 |
