| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NTM | neurotrimin | 0.0888226 |
| PEG10 | paternally expressed 10 | 0.0886567 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0856639 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0841596 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0752903 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0751212 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0717546 |
| APP | amyloid beta (A4) precursor protein | 0.0675419 |
| COL5A2 | collagen, type V, alpha 2 | 0.0634497 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0577259 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0542505 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0541167 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0530744 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0514788 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0502129 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0483709 |
| ENAH | enabled homolog (Drosophila) | 0.0475114 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0468951 |
| SPAG9 | sperm associated antigen 9 | 0.0467911 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0467898 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0453925 |
| KIF1B | kinesin family member 1B | 0.0445304 |
| CENPF | centromere protein F, 350/400kDa | 0.0437591 |
| NOP58 | NOP58 ribonucleoprotein | 0.042145 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0405125 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0400907 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0394349 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0394292 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0389394 |
| RPL3 | ribosomal protein L3 | 0.0380473 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0377964 |
| JMJD1C | jumonji domain containing 1C | 0.0377122 |
| SRPK2 | SRSF protein kinase 2 | 0.0374152 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0373142 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0365299 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0360214 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0358293 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.035783 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0356776 |
| MED13L | mediator complex subunit 13-like | 0.0346872 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0343427 |
| WDR43 | WD repeat domain 43 | 0.033935 |
| ZNF462 | zinc finger protein 462 | 0.0334075 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0328919 |
| EVI5 | ecotropic viral integration site 5 | 0.0327928 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0326819 |
| UTRN | utrophin | 0.0319251 |
| PLPP1 | phospholipid phosphatase 1 | 0.0317733 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0315182 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0315156 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0306989 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0306492 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0305682 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0303464 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0296447 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0292613 |
| GPHN | gephyrin | 0.0290756 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0289448 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0280513 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0278312 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0278263 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0276733 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0276245 |
| FMNL2 | formin-like 2 | 0.0275995 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0275707 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0274942 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0274586 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0272138 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0272105 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0258618 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0257915 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0256792 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0254807 |
| H1-0 | H1.0 linker histone | 0.0254663 |
| RNF213 | ring finger protein 213 | 0.0254631 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0254042 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0251996 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0250433 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0246464 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 | 0.024593 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0245042 |
| CDC14A | cell division cycle 14A | 0.0245008 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.024294 |
| PAPOLA | poly(A) polymerase alpha | 0.0239587 |
| SYT1 | synaptotagmin I | 0.0239237 |
| FAT1 | FAT atypical cadherin 1 | 0.0237881 |
| ZNF608 | zinc finger protein 608 | 0.0237567 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0237318 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0237064 |
| PCBP2 | poly(rC) binding protein 2 | 0.0236811 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0236214 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0235816 |
| MB21D2 | Mab-21 domain containing 2 | 0.0234108 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0233983 |
| ECT2 | epithelial cell transforming 2 | 0.0233299 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0233243 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0231362 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0231285 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0230599 |
| FAM135A | family with sequence similarity 135, member A | 0.0229906 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCDH9 | protocadherin 9 | -0.146503 |
| TMSB10 | thymosin beta 10 | -0.126926 |
| PTMA | prothymosin, alpha | -0.119209 |
| GPC3 | glypican 3 | -0.117241 |
| VIM | vimentin | -0.099862 |
| CADM2 | cell adhesion molecule 2 | -0.0993394 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.095387 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0876064 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0805595 |
| COL3A1 | collagen, type III, alpha 1 | -0.0799286 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0749952 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0676214 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0592032 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0569001 |
| RPLP1 | ribosomal protein, large, P1 | -0.0559011 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0553806 |
| RPS8 | ribosomal protein S8 | -0.0553221 |
| MEIS2 | Meis homeobox 2 | -0.0551878 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0543015 |
| FST | follistatin | -0.0504555 |
| RPL35A | ribosomal protein L35a | -0.0496001 |
| DMD | dystrophin | -0.0482919 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0428044 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0416746 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0411707 |
| RPLP0 | ribosomal protein, large, P0 | -0.0409527 |
| LDHA | lactate dehydrogenase A | -0.0398371 |
| PHIP | pleckstrin homology domain interacting protein | -0.0398237 |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) | -0.0393718 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0391038 |
| CALR | calreticulin | -0.0383775 |
| RPL31 | ribosomal protein L31 | -0.0380256 |
| RPS24 | ribosomal protein S24 | -0.036732 |
| GNAS | GNAS complex locus | -0.036511 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0364367 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0357572 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0350369 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0350311 |
| S100A10 | S100 calcium binding protein A10 | -0.034871 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.033479 |
| RASAL2 | RAS protein activator like 2 | -0.033119 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0326097 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0322692 |
| ITGAV | integrin, alpha V | -0.0320426 |
| TUBA1B | tubulin, alpha 1b | -0.0319745 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0319159 |
| PRELID2 | PRELI domain containing 2 | -0.0315588 |
| RPS13 | ribosomal protein S13 | -0.0314228 |
| RPS21 | ribosomal protein S21 | -0.0312435 |
| FTL | ferritin, light polypeptide | -0.0297542 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0293007 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0289139 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0287235 |
| RPS25 | ribosomal protein S25 | -0.0286686 |
| UPP1 | uridine phosphorylase 1 | -0.0281737 |
| RAI1 | retinoic acid induced 1 | -0.0278481 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0278268 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0274911 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0274011 |
| TFRC | transferrin receptor | -0.027155 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0270787 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0268854 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0266925 |
| PALLD | palladin, cytoskeletal associated protein | -0.0263005 |
| PGK1 | phosphoglycerate kinase 1 | -0.0261248 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0261061 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0258674 |
| NDRG1 | N-myc downstream regulated 1 | -0.0257667 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0257484 |
| RPL7A | ribosomal protein L7a | -0.0256869 |
| RPL34 | ribosomal protein L34 | -0.0256329 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | -0.0255113 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.025348 |
| TXNRD1 | thioredoxin reductase 1 | -0.0251868 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.024631 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0245314 |
| RPS19 | ribosomal protein S19 | -0.0238096 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0236104 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0234227 |
| RTN3 | reticulon 3 | -0.0232019 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0231747 |
| HMGA1 | high mobility group AT-hook 1 | -0.0231678 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0230354 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0230013 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0229757 |
| HMGA2 | high mobility group AT-hook 2 | -0.0229322 |
| TLK1 | tousled-like kinase 1 | -0.0227608 |
| SRP72 | signal recognition particle 72kDa | -0.0226813 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0226442 |
| CBX3 | chromobox homolog 3 | -0.0226409 |
| HM13 | histocompatibility (minor) 13 | -0.0225976 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0225536 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0224996 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0222058 |
| APOE | apolipoprotein E | -0.0221743 |
| TSPAN12 | tetraspanin 12 | -0.0221437 |
| EXOC2 | exocyst complex component 2 | -0.021882 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0217943 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0217312 |
| RPS23 | ribosomal protein S23 | -0.0216741 |
