| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.1023 |
| CD44 | CD44 molecule (Indian blood group) | 0.0938444 |
| ACTG1 | actin gamma 1 | 0.0659796 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0638334 |
| SMAD3 | SMAD family member 3 | 0.0608734 |
| ZFP36 | ZFP36 ring finger protein | 0.0575076 |
| ITGB5 | integrin, beta 5 | 0.0561933 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0561689 |
| RPLP2 | ribosomal protein, large, P2 | 0.0545223 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0523789 |
| RPL37A | ribosomal protein L37a | 0.0487576 |
| ACTN4 | actinin, alpha 4 | 0.0482402 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0468199 |
| RTN4 | reticulon 4 | 0.0463684 |
| RPS6 | ribosomal protein S6 | 0.0460372 |
| RPS21 | ribosomal protein S21 | 0.0447715 |
| RPL37 | ribosomal protein L37 | 0.0443551 |
| RPS2 | ribosomal protein S2 | 0.04399 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0436598 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0434473 |
| JMJD1C | jumonji domain containing 1C | 0.0433713 |
| RPL11 | ribosomal protein L11 | 0.0430028 |
| RPS16 | ribosomal protein S16 | 0.0418977 |
| RPS3 | ribosomal protein S3 | 0.0416865 |
| RPS12 | ribosomal protein S12 | 0.0411873 |
| RPL23 | ribosomal protein L23 | 0.0404995 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0391934 |
| RPS19 | ribosomal protein S19 | 0.0389866 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0378598 |
| RPL26 | ribosomal protein L26 | 0.0371208 |
| TMEM41B | transmembrane protein 41B | 0.0366894 |
| RPS8 | ribosomal protein S8 | 0.0352422 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0348653 |
| RPL35A | ribosomal protein L35a | 0.0348033 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0346982 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0345659 |
| RPS14 | ribosomal protein S14 | 0.0344055 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0328677 |
| THOC2 | THO complex 2 | 0.0328654 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0320731 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0318669 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0315756 |
| PHF14 | PHD finger protein 14 | 0.0311565 |
| ATP13A3 | ATPase type 13A3 | 0.0309981 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0309961 |
| RPL12 | ribosomal protein L12 | 0.0308609 |
| RPL28 | ribosomal protein L28 | 0.0307027 |
| RPL21 | ribosomal protein L21 | 0.0304633 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0303614 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0300866 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0299398 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0295221 |
| KLF6 | Kruppel-like factor 6 | 0.0290662 |
| SQSTM1 | sequestosome 1 | 0.0286776 |
| EFNA5 | ephrin-A5 | 0.0282405 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0281281 |
| RPL27 | ribosomal protein L27 | 0.0275664 |
| PFN1 | profilin 1 | 0.0274843 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0273697 |
| RPL36A | ribosomal protein L36a | 0.0271457 |
| PDE10A | phosphodiesterase 10A | 0.0270212 |
| RUNX1 | runt-related transcription factor 1 | 0.0265593 |
| HLA-B | major histocompatibility complex, class I, B | 0.0257684 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0255358 |
| HMGA1 | high mobility group AT-hook 1 | 0.0253588 |
| RBM25 | RNA binding motif protein 25 | 0.0253203 |
| SNX9 | sorting nexin 9 | 0.0249607 |
| DNMBP | dynamin binding protein | 0.0246538 |
| RPL30 | ribosomal protein L30 | 0.0241468 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0238354 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0237847 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0237044 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.023672 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.023644 |
| SATB2 | SATB homeobox 2 | 0.0235759 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0229005 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0227784 |
| KNOP1 | lysine-rich nucleolar protein 1 | 0.0225488 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0225386 |
| RNF145 | ring finger protein 145 | 0.0225156 |
| FOSL1 | FOS-like antigen 1 | 0.0224323 |
| MOSMO | modulator of smoothened | 0.0222535 |
| RPS10 | ribosomal protein S10 | 0.0221982 |
| FHL2 | four and a half LIM domains 2 | 0.0221753 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0221438 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0218827 |
| ANGPTL4 | angiopoietin-like 4 | 0.0217839 |
| RASAL2 | RAS protein activator like 2 | 0.0216732 |
| B2M | beta-2-microglobulin | 0.0216188 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0215587 |
| RPL36 | ribosomal protein L36 | 0.0215282 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0212391 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0211629 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0211602 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0210308 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0209344 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0207945 |
| DSTN | destrin (actin depolymerizing factor) | 0.0206556 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.020625 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0201309 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.306787 |
| AHNAK | AHNAK nucleoprotein | -0.220162 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.195758 |
| UBC | ubiquitin C | -0.149638 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.143624 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.13415 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.117597 |
| PTMA | prothymosin, alpha | -0.101506 |
| FBL | fibrillarin | -0.0911742 |
| VCL | vinculin | -0.0900759 |
| CANX | calnexin | -0.0893627 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0817976 |
| ENO1 | enolase 1, (alpha) | -0.0784845 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0773916 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0738136 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.070713 |
| LDHA | lactate dehydrogenase A | -0.0648759 |
| PKM | pyruvate kinase, muscle | -0.0624008 |
| TMSB10 | thymosin beta 10 | -0.0586334 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0533989 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0524711 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0510713 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0505269 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.049095 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0456246 |
| RPS27A | ribosomal protein S27a | -0.0455816 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.041721 |
| RPL4 | ribosomal protein L4 | -0.0413274 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0404782 |
| CALR | calreticulin | -0.0402346 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | -0.0402318 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0398662 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0398238 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0393886 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0393613 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0381918 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0381532 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0366061 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0365053 |
| RNF220 | ring finger protein 220 | -0.0361347 |
| MCL1 | myeloid cell leukemia 1 | -0.0355921 |
| ANLN | anillin, actin binding protein | -0.0348013 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0345252 |
| INTS6 | integrator complex subunit 6 | -0.0339295 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.032657 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.032647 |
| MKI67 | marker of proliferation Ki-67 | -0.0321342 |
| PCBP2 | poly(rC) binding protein 2 | -0.0317776 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0316809 |
| JUN | jun proto-oncogene | -0.0314179 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0313534 |
| TAOK1 | TAO kinase 1 | -0.0303044 |
| CTBP2 | C-terminal binding protein 2 | -0.0302942 |
| RPS5 | ribosomal protein S5 | -0.0300043 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0299699 |
| APP | amyloid beta (A4) precursor protein | -0.0292455 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0286945 |
| HDLBP | high density lipoprotein binding protein | -0.0286108 |
| ZNF207 | zinc finger protein 207 | -0.0285816 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0280623 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0280311 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0279283 |
| CALU | calumenin | -0.0279153 |
| CA8 | carbonic anhydrase VIII | -0.0276881 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0274422 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.027429 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0273438 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0272632 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0270963 |
| TPM3 | tropomyosin 3 | -0.0270062 |
| TNS3 | tensin 3 | -0.0269547 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.026505 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0259425 |
| NUP98 | nucleoporin 98kDa | -0.0258445 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0258324 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0258234 |
| MED29 | mediator complex subunit 29 | -0.025796 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0256673 |
| OGA | O-GlcNAcase | -0.0255643 |
| EHBP1 | EH domain binding protein 1 | -0.0255395 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0255224 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.025516 |
| DIAPH2 | diaphanous-related formin 2 | -0.0254831 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0253771 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0252866 |
| HYOU1 | hypoxia up-regulated 1 | -0.0249355 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0244457 |
| ATM | ATM serine/threonine kinase | -0.0243226 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0241166 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0240235 |
| VCP | valosin containing protein | -0.0239952 |
| USP34 | ubiquitin specific peptidase 34 | -0.0239202 |
| DST | dystonin | -0.0237835 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0233582 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0233156 |
| PGK1 | phosphoglycerate kinase 1 | -0.0233137 |
| SPAG9 | sperm associated antigen 9 | -0.023208 |
| IPO7 | importin 7 | -0.0231938 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0227613 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | -0.0225752 |
