| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | 0.176181 |
| COL6A2 | collagen, type VI, alpha 2 | 0.138949 |
| COL6A1 | collagen, type VI, alpha 1 | 0.107474 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0897422 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.086642 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0825331 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0818017 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0781873 |
| COL5A1 | collagen, type V, alpha 1 | 0.0749072 |
| HLA-A | major histocompatibility complex, class I, A | 0.0731253 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0717324 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0694846 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0679711 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0658541 |
| MMP2 | matrix metallopeptidase 2 | 0.0653041 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0627976 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0624615 |
| TMEM178B | transmembrane protein 178B | 0.0609466 |
| SMAD3 | SMAD family member 3 | 0.0595513 |
| STC1 | stanniocalcin 1 | 0.0587729 |
| NAV1 | neuron navigator 1 | 0.0583099 |
| FAM20C | family with sequence similarity 20, member C | 0.0583086 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0580729 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0580085 |
| VEGFA | vascular endothelial growth factor A | 0.0551251 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0520288 |
| LOXL2 | lysyl oxidase-like 2 | 0.0514586 |
| B2M | beta-2-microglobulin | 0.0504558 |
| ECE1 | endothelin converting enzyme 1 | 0.0499683 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.0498991 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0493054 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0469021 |
| IFI44L | interferon-induced protein 44-like | 0.0442595 |
| ANGPTL4 | angiopoietin-like 4 | 0.0435345 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0430375 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0425528 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.04175 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0417216 |
| MTSS1 | metastasis suppressor 1 | 0.0407343 |
| PLEC | plectin | 0.0399373 |
| COL5A3 | collagen, type V, alpha 3 | 0.0399206 |
| TGM2 | transglutaminase 2 | 0.0398457 |
| SVIL | supervillin | 0.0379329 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0377789 |
| CADM1 | cell adhesion molecule 1 | 0.0375519 |
| NRP1 | neuropilin 1 | 0.0374774 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.034971 |
| PCBP3 | poly(rC) binding protein 3 | 0.0348934 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0345757 |
| H1-0 | H1.0 linker histone | 0.034171 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0337967 |
| SEPTIN9 | septin 9 | 0.0337469 |
| HPCAL1 | hippocalcin-like 1 | 0.0337251 |
| SFTPA2 | surfactant protein A2 | 0.0336498 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.032938 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0328223 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0324707 |
| MCL1 | myeloid cell leukemia 1 | 0.0322205 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | 0.0314315 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0310116 |
| RPS6 | ribosomal protein S6 | 0.0307252 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0307049 |
| HSPA8 | heat shock 70kDa protein 8 | 0.030302 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0301619 |
| EGR1 | early growth response 1 | 0.0297038 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0287855 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0287614 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0285099 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.028356 |
| AGRN | agrin | 0.0282925 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0277754 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0277037 |
| SQSTM1 | sequestosome 1 | 0.0276981 |
| HMGA2 | high mobility group AT-hook 2 | 0.02765 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0275618 |
| ATP13A3 | ATPase type 13A3 | 0.0275456 |
| FAT1 | FAT atypical cadherin 1 | 0.0273177 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0269094 |
| MX2 | MX dynamin-like GTPase 2 | 0.0267741 |
| HDAC9 | histone deacetylase 9 | 0.0267562 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0267524 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0265227 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0264605 |
| C1D | C1D nuclear receptor corepressor | 0.0264406 |
| PLD3 | phospholipase D family, member 3 | 0.0263105 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0257522 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0257205 |
| RPL28 | ribosomal protein L28 | 0.0255651 |
| FHIT | fragile histidine triad | 0.0253915 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0250041 |
| APP | amyloid beta (A4) precursor protein | 0.0248247 |
| RNF213 | ring finger protein 213 | 0.0247957 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.024607 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0243331 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0242852 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0242686 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0240052 |
| HLA-E | major histocompatibility complex, class I, E | 0.0239828 |
| STK10 | serine/threonine kinase 10 | 0.0238333 |
| AEBP1 | AE binding protein 1 | 0.0232579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.223738 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.119192 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.104134 |
| TMSB10 | thymosin beta 10 | -0.0927076 |
| NDRG1 | N-myc downstream regulated 1 | -0.0889416 |
| PTMA | prothymosin, alpha | -0.0770148 |
| CENPF | centromere protein F, 350/400kDa | -0.0723901 |
| PKM | pyruvate kinase, muscle | -0.0716621 |
| PGK1 | phosphoglycerate kinase 1 | -0.0613502 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0607441 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.054586 |
| ZNF292 | zinc finger protein 292 | -0.0532484 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0500653 |
| ANLN | anillin, actin binding protein | -0.0491417 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0462167 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0452929 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0446054 |
| RBM39 | RNA binding motif protein 39 | -0.0435749 |
| SMC4 | structural maintenance of chromosomes 4 | -0.04344 |
| SEPTIN7 | septin 7 | -0.0432374 |
| TPX2 | TPX2, microtubule-associated | -0.0419878 |
| THBS1 | thrombospondin 1 | -0.0395297 |
| MKI67 | marker of proliferation Ki-67 | -0.0382942 |
| FTL | ferritin, light polypeptide | -0.0381377 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0378313 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0375432 |
| GOLGA4 | golgin A4 | -0.0362921 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.036041 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0345261 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0340334 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0338595 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.033414 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.031964 |
| RRBP1 | ribosome binding protein 1 | -0.0312534 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0312327 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0311549 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0311521 |
| DIAPH3 | diaphanous-related formin 3 | -0.0305459 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0305447 |
| CALD1 | caldesmon 1 | -0.0305177 |
| XPO1 | exportin 1 | -0.0302591 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0301912 |
| IER3 | immediate early response 3 | -0.02987 |
| HMGB2 | high mobility group box 2 | -0.0297144 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0296655 |
| MORF4L2 | mortality factor 4 like 2 | -0.0292788 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0291495 |
| TFG | TRK-fused gene | -0.0284311 |
| POTEF | POTE ankyrin domain family, member F | -0.0281167 |
| SPAG9 | sperm associated antigen 9 | -0.0276274 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.027343 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0273428 |
| CLTC | clathrin, heavy chain (Hc) | -0.027184 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.026796 |
| RPS24 | ribosomal protein S24 | -0.0267537 |
| SGO2 | shugoshin 2 | -0.0267479 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0263624 |
| MATR3 | matrin 3 | -0.0260879 |
| SEC24D | SEC24 family member D | -0.0259628 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0258842 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0257707 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0256821 |
| CENPE | centromere protein E, 312kDa | -0.0251229 |
| TMEM263 | transmembrane protein 263 | -0.0251169 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0250725 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0248857 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.024715 |
| CBX3 | chromobox homolog 3 | -0.024334 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0243249 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.024263 |
| RYBP | RING1 and YY1 binding protein | -0.0241966 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0237968 |
| ECT2 | epithelial cell transforming 2 | -0.0236718 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0236258 |
| INHBA | inhibin, beta A | -0.0235857 |
| KIF4A | kinesin family member 4A | -0.0230712 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0229891 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0228868 |
| QKI | QKI, KH domain containing, RNA binding | -0.0227585 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0226693 |
| CDH13 | cadherin 13 | -0.0225047 |
| CLINT1 | clathrin interactor 1 | -0.0225008 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0221759 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0221405 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0221084 |
| GNAS | GNAS complex locus | -0.0217641 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0214831 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0212879 |
| FAM162A | family with sequence similarity 162, member A | -0.0212544 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0211788 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0209566 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.020895 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.020844 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0204275 |
| FN1 | fibronectin 1 | -0.0204052 |
| ITGA1 | integrin, alpha 1 | -0.0203514 |
| TPM4 | tropomyosin 4 | -0.020318 |
| TKT | transketolase | -0.0202306 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0200887 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0200391 |
