| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0976615 |
| MCL1 | myeloid cell leukemia 1 | 0.0962206 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0814743 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0630883 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0496911 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.0464962 |
| NBEA | neurobeachin | 0.0437818 |
| RPL37A | ribosomal protein L37a | 0.0425006 |
| PDE10A | phosphodiesterase 10A | 0.0424929 |
| GPC6 | glypican 6 | 0.0417566 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.040914 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0392457 |
| SMYD3 | SET and MYND domain containing 3 | 0.0378348 |
| STC1 | stanniocalcin 1 | 0.0372459 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0371469 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0369187 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0346985 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0346029 |
| PNN | pinin, desmosome associated protein | 0.0341185 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0339886 |
| CPE | carboxypeptidase E | 0.0338267 |
| SIK2 | salt-inducible kinase 2 | 0.0337726 |
| ZFHX3 | zinc finger homeobox 3 | 0.0336612 |
| EFNA5 | ephrin-A5 | 0.0335176 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0331267 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0330017 |
| NAV2 | neuron navigator 2 | 0.0314134 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0306292 |
| RORA | RAR-related orphan receptor A | 0.0302845 |
| CALCA | calcitonin-related polypeptide alpha | 0.0302693 |
| SCFD1 | sec1 family domain containing 1 | 0.0294891 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0292545 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0284174 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0277333 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0269551 |
| SETX | senataxin | 0.0269248 |
| ASPH | aspartate beta-hydroxylase | 0.0268377 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.026504 |
| NRG1 | neuregulin 1 | 0.0261804 |
| POTEF | POTE ankyrin domain family, member F | 0.0259763 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0258157 |
| TMEM255B | transmembrane protein 255B | 0.0257843 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0256225 |
| RPS12 | ribosomal protein S12 | 0.0255603 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0250152 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0244206 |
| RPS6 | ribosomal protein S6 | 0.0238028 |
| PHF14 | PHD finger protein 14 | 0.0237725 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0237656 |
| GSE1 | Gse1 coiled-coil protein | 0.0236862 |
| MSN | moesin | 0.0236443 |
| VEGFA | vascular endothelial growth factor A | 0.0236188 |
| KIF26B | kinesin family member 26B | 0.023364 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.023224 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0231205 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.02306 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0230525 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0226985 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.022662 |
| SIK3 | SIK family kinase 3 | 0.0224648 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0224131 |
| PAEP | progestagen-associated endometrial protein | 0.0223809 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0222747 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0222457 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0221441 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0218577 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0216807 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0214592 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0212125 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.02103 |
| TOP1 | topoisomerase (DNA) I | 0.0209519 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0209488 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0209362 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0208135 |
| RPS2 | ribosomal protein S2 | 0.0207345 |
| INTS1 | integrator complex subunit 1 | 0.0206128 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0205644 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0205627 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0205287 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.020471 |
| SCFD2 | sec1 family domain containing 2 | 0.0202364 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0200652 |
| INHBA | inhibin, beta A | 0.0200118 |
| SVIL | supervillin | 0.019609 |
| INTS6 | integrator complex subunit 6 | 0.019597 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0195111 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0190096 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0189739 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0189739 |
| ATF6 | activating transcription factor 6 | 0.018879 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0188516 |
| FAM13A | family with sequence similarity 13, member A | 0.0187039 |
| PARD3 | par-3 family cell polarity regulator | 0.0185849 |
| GRAMD1B | GRAM domain containing 1B | 0.0185661 |
| NANOS1 | nanos homolog 1 (Drosophila) | 0.018344 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0182748 |
| AUTS2 | autism susceptibility candidate 2 | 0.0181166 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.0180177 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0180046 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0179701 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.169726 |
| TENM1 | teneurin transmembrane protein 1 | -0.130441 |
| PEG10 | paternally expressed 10 | -0.116659 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103543 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0974239 |
| CENPF | centromere protein F, 350/400kDa | -0.0828495 |
| ENO1 | enolase 1, (alpha) | -0.0780299 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0649497 |
| RAD21 | RAD21 homolog (S. pombe) | -0.064048 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0616517 |
| MKI67 | marker of proliferation Ki-67 | -0.0581275 |
| GPC5 | glypican 5 | -0.0570216 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0560833 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0520983 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0511525 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0507513 |
| TMSB4X | thymosin beta 4, X-linked | -0.0503852 |
| SNTG1 | syntrophin, gamma 1 | -0.0474386 |
| PGK1 | phosphoglycerate kinase 1 | -0.0472898 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0446543 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0437376 |
| H1-0 | H1.0 linker histone | -0.0430666 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0430308 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0416247 |
| RIT2 | Ras-like without CAAX 2 | -0.041531 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0403564 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0396908 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0392546 |
| FOXC1 | forkhead box C1 | -0.0386841 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.03854 |
| PCDH9 | protocadherin 9 | -0.0382165 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0381898 |
| TUBB | tubulin, beta class I | -0.0375023 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0372596 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0370548 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0369311 |
| ZNF292 | zinc finger protein 292 | -0.036228 |
| SCG2 | secretogranin II | -0.0359281 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0357983 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0355587 |
| RPL4 | ribosomal protein L4 | -0.0353895 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0351426 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0345991 |
| UBB | ubiquitin B | -0.0345269 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0342688 |
| GNAS | GNAS complex locus | -0.0341996 |
| FTL | ferritin, light polypeptide | -0.0336804 |
| MAP1B | microtubule-associated protein 1B | -0.0333042 |
| TPR | translocated promoter region, nuclear basket protein | -0.0331717 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0324785 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0316694 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0313265 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.030721 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0303084 |
| TKT | transketolase | -0.030095 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0299774 |
| KNL1 | kinetochore scaffold 1 | -0.0297625 |
| RPL6 | ribosomal protein L6 | -0.0297085 |
| SRP72 | signal recognition particle 72kDa | -0.0294516 |
| KIAA0825 | KIAA0825 | -0.0292241 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0286442 |
| AGBL4 | ATP/GTP binding protein-like 4 | -0.028512 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0283926 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0280552 |
| SGO2 | shugoshin 2 | -0.0275043 |
| HMGB1 | high mobility group box 1 | -0.0274586 |
| NCKAP5 | NCK-associated protein 5 | -0.0272859 |
| RTN4 | reticulon 4 | -0.0272394 |
| FAM162A | family with sequence similarity 162, member A | -0.0272182 |
| TPX2 | TPX2, microtubule-associated | -0.0268764 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0264309 |
| TXNRD1 | thioredoxin reductase 1 | -0.0264094 |
| WDR45B | WD repeat domain 45B | -0.0261761 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0261454 |
| RPS5 | ribosomal protein S5 | -0.0261262 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0260271 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0258051 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0256584 |
| CANX | calnexin | -0.0256382 |
| NFIA | nuclear factor I/A | -0.0256173 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0254131 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0253267 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0253041 |
| RPL35A | ribosomal protein L35a | -0.0251962 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0249542 |
| DEK | DEK proto-oncogene | -0.0248635 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0248262 |
| TMEM123 | transmembrane protein 123 | -0.0245712 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0239189 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0238134 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0237484 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0236826 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0235832 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0235794 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0234239 |
| HMGB2 | high mobility group box 2 | -0.0232981 |
| RRBP1 | ribosome binding protein 1 | -0.0232515 |
| S100A9 | S100 calcium binding protein A9 | -0.0232075 |
| ANLN | anillin, actin binding protein | -0.0231413 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0231089 |
