| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.10592 |
| NAV2 | neuron navigator 2 | 0.0946827 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.093394 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0911676 |
| VEGFA | vascular endothelial growth factor A | 0.0775664 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0773857 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.074293 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0705256 |
| SMAD3 | SMAD family member 3 | 0.0679452 |
| PDE10A | phosphodiesterase 10A | 0.0651515 |
| MSN | moesin | 0.0623281 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0589161 |
| CD44 | CD44 molecule (Indian blood group) | 0.0566934 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0559848 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0506382 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0481765 |
| JMJD1C | jumonji domain containing 1C | 0.0481011 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0476838 |
| GOLGA4 | golgin A4 | 0.0472102 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0448418 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.043919 |
| RPS12 | ribosomal protein S12 | 0.0433781 |
| NDRG1 | N-myc downstream regulated 1 | 0.0426289 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0423603 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0417029 |
| RUNX1 | runt-related transcription factor 1 | 0.0412731 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0409873 |
| CADM1 | cell adhesion molecule 1 | 0.0405786 |
| FMNL2 | formin-like 2 | 0.0395151 |
| MYOF | myoferlin | 0.0393057 |
| C3 | complement component 3 | 0.0387165 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0383169 |
| HLA-A | major histocompatibility complex, class I, A | 0.038223 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0371796 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0365953 |
| FLNB | filamin B, beta | 0.0363993 |
| AFDN | afadin, adherens junction formation factor | 0.0361562 |
| HELZ | helicase with zinc finger | 0.03612 |
| MT2A | metallothionein 2A | 0.0360829 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0352096 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347841 |
| GPC6 | glypican 6 | 0.0335213 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.033035 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.032984 |
| ANKRD11 | ankyrin repeat domain 11 | 0.032723 |
| ADM | adrenomedullin | 0.0327172 |
| SEPTIN9 | septin 9 | 0.0327094 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0325347 |
| ZNF292 | zinc finger protein 292 | 0.0324611 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0321998 |
| ANO6 | anoctamin 6 | 0.0321066 |
| RPS2 | ribosomal protein S2 | 0.0319323 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0314705 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0313847 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0313692 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0306901 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0306401 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0305679 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0300717 |
| BBX | bobby sox homolog (Drosophila) | 0.0296588 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0294639 |
| RPS6 | ribosomal protein S6 | 0.0291866 |
| VCAN | versican | 0.0288912 |
| TGM2 | transglutaminase 2 | 0.0287095 |
| ATXN1 | ataxin 1 | 0.0281249 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0278856 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0278143 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0274703 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0272245 |
| STC2 | stanniocalcin 2 | 0.0271296 |
| APP | amyloid beta (A4) precursor protein | 0.0267839 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0263873 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0261197 |
| ATP13A3 | ATPase type 13A3 | 0.0259963 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0256336 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0254518 |
| TNS3 | tensin 3 | 0.0253237 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0253082 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0251152 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0250398 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0248038 |
| CD109 | CD109 molecule | 0.0246826 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0244269 |
| RPL37A | ribosomal protein L37a | 0.0243632 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0242558 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.02425 |
| SQSTM1 | sequestosome 1 | 0.0241713 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0240053 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0238894 |
| DUSP5 | dual specificity phosphatase 5 | 0.023782 |
| STC1 | stanniocalcin 1 | 0.0237767 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0237764 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0236804 |
| FAM120A | family with sequence similarity 120A | 0.0235603 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0231357 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0229474 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0226936 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0226576 |
| LOXL2 | lysyl oxidase-like 2 | 0.0223078 |
| EZR | ezrin | 0.022213 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.122309 |
| VIM | vimentin | -0.110969 |
| FTL | ferritin, light polypeptide | -0.105052 |
| VCL | vinculin | -0.0881055 |
| FN1 | fibronectin 1 | -0.0803716 |
| IER3 | immediate early response 3 | -0.0670233 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0615473 |
| RPS24 | ribosomal protein S24 | -0.0614691 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0583409 |
| RPL35A | ribosomal protein L35a | -0.0568591 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0510651 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0486447 |
| HLA-E | major histocompatibility complex, class I, E | -0.0450509 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0440053 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0432895 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0387662 |
| PTMA | prothymosin, alpha | -0.0382332 |
| RPLP1 | ribosomal protein, large, P1 | -0.0368274 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0345046 |
| COL1A1 | collagen, type I, alpha 1 | -0.0341074 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0340958 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0337716 |
| SP100 | SP100 nuclear antigen | -0.03286 |
| COL1A2 | collagen, type I, alpha 2 | -0.0320888 |
| TMSB4X | thymosin beta 4, X-linked | -0.0315674 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0310795 |
| GNAS | GNAS complex locus | -0.030875 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0302555 |
| RPL32 | ribosomal protein L32 | -0.0285302 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0264424 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0260384 |
| RPL19 | ribosomal protein L19 | -0.0253902 |
| TMEM263 | transmembrane protein 263 | -0.0252844 |
| CAVIN1 | caveolae associated protein 1 | -0.0247159 |
| RRBP1 | ribosome binding protein 1 | -0.0246068 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0240491 |
| PALLD | palladin, cytoskeletal associated protein | -0.0235291 |
| RPS4X | ribosomal protein S4, X-linked | -0.0233275 |
| CLIC4 | chloride intracellular channel 4 | -0.0227977 |
| NABP1 | nucleic acid binding protein 1 | -0.0227897 |
| RPS5 | ribosomal protein S5 | -0.0226077 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0225339 |
| BICC1 | BicC family RNA binding protein 1 | -0.0225275 |
| NRN1 | neuritin 1 | -0.0221343 |
| AHNAK | AHNAK nucleoprotein | -0.0220195 |
| TKT | transketolase | -0.021426 |
| RPL34 | ribosomal protein L34 | -0.0212236 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0210034 |
| KLF6 | Kruppel-like factor 6 | -0.0209271 |
| ARF1 | ADP-ribosylation factor 1 | -0.0206394 |
| CDH13 | cadherin 13 | -0.020634 |
| RPL4 | ribosomal protein L4 | -0.0206166 |
| RIGI | RNA sensor RIG-I | -0.0203779 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0200787 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0196556 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0195489 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0195488 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0192407 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0184664 |
| CUL4B | cullin 4B | -0.0183728 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0180861 |
| NPR2 | natriuretic peptide receptor 2 | -0.0180072 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.017755 |
| THBS1 | thrombospondin 1 | -0.0177354 |
| SRGN | serglycin | -0.017403 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0170645 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0170075 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.016856 |
| HDLBP | high density lipoprotein binding protein | -0.0167771 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.016698 |
| SRP72 | signal recognition particle 72kDa | -0.0165002 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.016453 |
| HMGA2 | high mobility group AT-hook 2 | -0.0163168 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0162943 |
| CDK12 | cyclin-dependent kinase 12 | -0.0162575 |
| DIAPH2 | diaphanous-related formin 2 | -0.0161935 |
| ZNF217 | zinc finger protein 217 | -0.0160673 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0159174 |
| RPL31 | ribosomal protein L31 | -0.0157619 |
| CANX | calnexin | -0.015718 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0153343 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0153113 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0152877 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0152755 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.01513 |
| CD164 | CD164 molecule, sialomucin | -0.0150669 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0149926 |
| CTSD | cathepsin D | -0.0145325 |
| RPS21 | ribosomal protein S21 | -0.0142834 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0142408 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0141655 |
| CP | ceruloplasmin (ferroxidase) | -0.0141462 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0140781 |
| TUBB | tubulin, beta class I | -0.014078 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0139883 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0138383 |
| KLHL5 | kelch-like family member 5 | -0.0138051 |
| MIDN | midnolin | -0.0137883 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0137291 |
| SERINC3 | serine incorporator 3 | -0.013707 |
