| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.0802716 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0788017 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0766616 |
| ANKRD28 | ankyrin repeat domain 28 | 0.067081 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0640439 |
| MIS18BP1 | MIS18 binding protein 1 | 0.059562 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0595512 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0575378 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0569822 |
| SMYD3 | SET and MYND domain containing 3 | 0.0555079 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.055277 |
| FMNL2 | formin-like 2 | 0.0548219 |
| RAD51B | RAD51 paralog B | 0.054414 |
| NAV2 | neuron navigator 2 | 0.0542714 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0540112 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0536847 |
| SET | SET nuclear proto-oncogene | 0.0533657 |
| GOLGA4 | golgin A4 | 0.053113 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0517638 |
| MSN | moesin | 0.0510765 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0489091 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0484145 |
| ATP13A3 | ATPase type 13A3 | 0.0450356 |
| SETD5 | SET domain containing 5 | 0.0448058 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0447794 |
| HDAC9 | histone deacetylase 9 | 0.0429208 |
| CEP250 | centrosomal protein 250kDa | 0.0426336 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0423967 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0423121 |
| YBX3 | Y box binding protein 3 | 0.0421709 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0420261 |
| RNF145 | ring finger protein 145 | 0.041729 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0408895 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0404512 |
| YAP1 | Yes-associated protein 1 | 0.0403406 |
| PRKCA | protein kinase C, alpha | 0.0398678 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0396632 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0390577 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0385291 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0382605 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0381835 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0375845 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0371939 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0369868 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0369859 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0369209 |
| MED13 | mediator complex subunit 13 | 0.0357404 |
| DIAPH1 | diaphanous-related formin 1 | 0.0353673 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0348081 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0347626 |
| HELZ | helicase with zinc finger | 0.0346628 |
| DIAPH3 | diaphanous-related formin 3 | 0.0344403 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0339325 |
| ZNF638 | zinc finger protein 638 | 0.0339017 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0338375 |
| ANXA1 | annexin A1 | 0.0336522 |
| RBM39 | RNA binding motif protein 39 | 0.0333811 |
| STK24 | serine/threonine kinase 24 | 0.0333151 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0331528 |
| EXOC6B | exocyst complex component 6B | 0.0330645 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0329477 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0327158 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0324663 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0324479 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0321486 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0315207 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.031349 |
| RUNX1 | runt-related transcription factor 1 | 0.0312969 |
| FNIP1 | folliculin interacting protein 1 | 0.0311515 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0311066 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0307468 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0305883 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0305024 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0304569 |
| NAV3 | neuron navigator 3 | 0.0302647 |
| AFDN | afadin, adherens junction formation factor | 0.0302009 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.030176 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0301317 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0299146 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0297114 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0296539 |
| LAMA5 | laminin, alpha 5 | 0.0296344 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0294464 |
| ITGB5 | integrin, beta 5 | 0.0293882 |
| NUP153 | nucleoporin 153kDa | 0.0287844 |
| WWOX | WW domain containing oxidoreductase | 0.0284152 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.0283849 |
| MAP4 | microtubule-associated protein 4 | 0.0280678 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0279463 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0279147 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0278662 |
| SATB2 | SATB homeobox 2 | 0.0278449 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0272333 |
| KIF5B | kinesin family member 5B | 0.0271797 |
| TOP1 | topoisomerase (DNA) I | 0.0269131 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.0269057 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.026758 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0265975 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0265888 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0264727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.168757 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.143823 |
| PTMA | prothymosin, alpha | -0.118628 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.116606 |
| VIM | vimentin | -0.113575 |
| LDHA | lactate dehydrogenase A | -0.0949069 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0851445 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0760949 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0656873 |
| AHNAK | AHNAK nucleoprotein | -0.0652696 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0619666 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0575864 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0574107 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0558416 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0534508 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0526424 |
| NDRG1 | N-myc downstream regulated 1 | -0.0525158 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0490327 |
| S100A10 | S100 calcium binding protein A10 | -0.0487419 |
| IGF2 | insulin-like growth factor 2 | -0.0486947 |
| HMGA2 | high mobility group AT-hook 2 | -0.0482551 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0457453 |
| RPL31 | ribosomal protein L31 | -0.0454245 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0449832 |
| GNAS | GNAS complex locus | -0.0446636 |
| CANX | calnexin | -0.0440004 |
| PGK1 | phosphoglycerate kinase 1 | -0.0436324 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0433951 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427016 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.04241 |
| TPM4 | tropomyosin 4 | -0.0418358 |
| PODXL | podocalyxin-like | -0.0390009 |
| RAI14 | retinoic acid induced 14 | -0.0386289 |
| ACTG1 | actin gamma 1 | -0.0364351 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0363637 |
| GPC6 | glypican 6 | -0.0348682 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0341704 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0341554 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0333683 |
| ATM | ATM serine/threonine kinase | -0.0329453 |
| ARFGEF3 | ARFGEF family member 3 | -0.0328789 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0326271 |
| RPL35A | ribosomal protein L35a | -0.0326 |
| RRBP1 | ribosome binding protein 1 | -0.0316408 |
| CLINT1 | clathrin interactor 1 | -0.0314935 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0314106 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.030854 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0307036 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0303637 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0293228 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0291 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0289245 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0286744 |
| ANXA4 | annexin A4 | -0.0285256 |
| SDC4 | syndecan 4 | -0.0283927 |
| MYO9A | myosin IXA | -0.0280662 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0280561 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0276067 |
| PRSS23 | protease, serine, 23 | -0.027568 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0272321 |
| ACER3 | alkaline ceramidase 3 | -0.0270562 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0270022 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0265659 |
| TMEM123 | transmembrane protein 123 | -0.0264789 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0263221 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0261348 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0261179 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.025919 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0258146 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0258044 |
| FTL | ferritin, light polypeptide | -0.0254086 |
| XPOT | exportin, tRNA | -0.025405 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.025119 |
| MYOF | myoferlin | -0.025098 |
| CCND1 | cyclin D1 | -0.0249207 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0247903 |
| LMNA | lamin A/C | -0.0247467 |
| NPR2 | natriuretic peptide receptor 2 | -0.0246497 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0246212 |
| PURA | purine-rich element binding protein A | -0.0245625 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0245049 |
| RPS8 | ribosomal protein S8 | -0.024237 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0242103 |
| CAVIN1 | caveolae associated protein 1 | -0.024209 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0241316 |
| S100A6 | S100 calcium binding protein A6 | -0.0241013 |
| RIGI | RNA sensor RIG-I | -0.023851 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0237458 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0236758 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.023444 |
| PCED1B | PC-esterase domain containing 1B | -0.0233854 |
| TMEM263 | transmembrane protein 263 | -0.022926 |
| CD63 | CD63 molecule | -0.022865 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0227286 |
| IER3 | immediate early response 3 | -0.022467 |
| FBXO11 | F-box protein 11 | -0.0222389 |
| COL5A1 | collagen, type V, alpha 1 | -0.022169 |
| ASTN2 | astrotactin 2 | -0.0221474 |
| CRBN | cereblon | -0.0216445 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0216125 |
