| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.132985 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.108698 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0845037 |
| ATXN1 | ataxin 1 | 0.0758867 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.075512 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0563862 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0561558 |
| SNX9 | sorting nexin 9 | 0.0539108 |
| EZR | ezrin | 0.0498396 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0456578 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0432328 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0417215 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0416985 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0414795 |
| RPL3 | ribosomal protein L3 | 0.0409911 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0390251 |
| EGFR | epidermal growth factor receptor | 0.0390177 |
| CPOX | coproporphyrinogen oxidase | 0.0385283 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0375757 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0373453 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0365037 |
| FHIT | fragile histidine triad | 0.0364996 |
| MT2A | metallothionein 2A | 0.0364722 |
| PRELID2 | PRELI domain containing 2 | 0.0354405 |
| ACTG1 | actin gamma 1 | 0.0353579 |
| EGR1 | early growth response 1 | 0.0352653 |
| ZNRF3 | zinc and ring finger 3 | 0.0351733 |
| CENPF | centromere protein F, 350/400kDa | 0.0341198 |
| NAV2 | neuron navigator 2 | 0.0337406 |
| POTEF | POTE ankyrin domain family, member F | 0.0337281 |
| EPHA2 | EPH receptor A2 | 0.0328717 |
| GPHN | gephyrin | 0.03286 |
| SLTM | SAFB-like, transcription modulator | 0.0326249 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0325614 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0323809 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0323553 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0321304 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.032062 |
| FHL2 | four and a half LIM domains 2 | 0.0311812 |
| FAT1 | FAT atypical cadherin 1 | 0.0309678 |
| YAP1 | Yes-associated protein 1 | 0.030924 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0305341 |
| VMP1 | vacuole membrane protein 1 | 0.0303877 |
| BRD2 | bromodomain containing 2 | 0.0302693 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0302513 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0300648 |
| ACTN4 | actinin, alpha 4 | 0.0296879 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0295589 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0288698 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.028666 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0284972 |
| FLNA | filamin A, alpha | 0.0284362 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0283455 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0278313 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0275997 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0274599 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0272661 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0270001 |
| USP6NL | USP6 N-terminal like | 0.0269864 |
| PARD3 | par-3 family cell polarity regulator | 0.0268804 |
| RNF43 | ring finger protein 43 | 0.0268379 |
| RPL37A | ribosomal protein L37a | 0.0268211 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0265908 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0265383 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0264264 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0255086 |
| RPLP2 | ribosomal protein, large, P2 | 0.0253718 |
| SLMAP | sarcolemma associated protein | 0.0250838 |
| ZNF292 | zinc finger protein 292 | 0.0249692 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0249305 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.024927 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0248029 |
| BBX | bobby sox homolog (Drosophila) | 0.0247287 |
| TXNIP | thioredoxin interacting protein | 0.0245998 |
| SEPTIN9 | septin 9 | 0.0245833 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0242236 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0241594 |
| PCBP2 | poly(rC) binding protein 2 | 0.0241399 |
| RPS19 | ribosomal protein S19 | 0.0241393 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0240997 |
| SDC4 | syndecan 4 | 0.0240443 |
| RPS2 | ribosomal protein S2 | 0.0239754 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0239532 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0235392 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0235144 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.02346 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0232787 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0231688 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0230673 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0228404 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0225984 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0222228 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0221796 |
| ITGA6 | integrin, alpha 6 | 0.0221751 |
| ASPH | aspartate beta-hydroxylase | 0.0220953 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0220392 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0219714 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0218738 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0218199 |
| PKP4 | plakophilin 4 | 0.0218056 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.336325 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.247987 |
| PTMA | prothymosin, alpha | -0.168281 |
| IER3 | immediate early response 3 | -0.101115 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0742191 |
| HDAC2 | histone deacetylase 2 | -0.0718131 |
| RPS24 | ribosomal protein S24 | -0.0689266 |
| FERMT1 | fermitin family member 1 | -0.0622011 |
| LAMB3 | laminin, beta 3 | -0.0610777 |
| LMO7 | LIM domain 7 | -0.0609443 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.06079 |
| SERINC5 | serine incorporator 5 | -0.0585418 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0550273 |
| CANX | calnexin | -0.0461435 |
| KRT18 | keratin 18, type I | -0.044545 |
| VCL | vinculin | -0.0445096 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0433681 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0403503 |
| RPL35A | ribosomal protein L35a | -0.0399813 |
| RPL4 | ribosomal protein L4 | -0.0369118 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0351324 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0344786 |
| MTAP | methylthioadenosine phosphorylase | -0.0342867 |
| FLOT1 | flotillin 1 | -0.0338329 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.032862 |
| TMEM123 | transmembrane protein 123 | -0.0319605 |
| LDHA | lactate dehydrogenase A | -0.0316675 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0309144 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.030526 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0303941 |
| PERP | PERP, TP53 apoptosis effector | -0.0297306 |
| RPL34 | ribosomal protein L34 | -0.0285336 |
| LAMA4 | laminin, alpha 4 | -0.0284774 |
| DSPP | dentin sialophosphoprotein | -0.0282475 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0273607 |
| CCND1 | cyclin D1 | -0.0273264 |
| TMSB10 | thymosin beta 10 | -0.0272624 |
| GDF15 | growth differentiation factor 15 | -0.0259712 |
| FMN1 | formin 1 | -0.025763 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0253527 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0243094 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0238593 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0235195 |
| RPL23 | ribosomal protein L23 | -0.0234235 |
| RCOR1 | REST corepressor 1 | -0.0229787 |
| RAB10 | RAB10, member RAS oncogene family | -0.0228371 |
| OXSR1 | oxidative stress responsive 1 | -0.0228342 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0228324 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.022549 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.022393 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0222364 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0219977 |
| TOP1 | topoisomerase (DNA) I | -0.0218278 |
| EPCAM | epithelial cell adhesion molecule | -0.0214239 |
| S100A6 | S100 calcium binding protein A6 | -0.0213579 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0212937 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0210848 |
| RPL6 | ribosomal protein L6 | -0.0204673 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0203608 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0203448 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0201674 |
| GPC5 | glypican 5 | -0.0199094 |
| RPL7 | ribosomal protein L7 | -0.0194243 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0191185 |
| TKT | transketolase | -0.0190647 |
| CDK13 | cyclin-dependent kinase 13 | -0.0188738 |
| DSC3 | desmocollin 3 | -0.01886 |
| RPL12 | ribosomal protein L12 | -0.0186868 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0185145 |
| AOPEP | aminopeptidase O (putative) | -0.0183102 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0182513 |
| TUBB | tubulin, beta class I | -0.0180142 |
| CALR | calreticulin | -0.0177256 |
| RPS25 | ribosomal protein S25 | -0.0177146 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0176305 |
| RPS27A | ribosomal protein S27a | -0.0173248 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0166554 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0164841 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0162224 |
| OXR1 | oxidation resistance 1 | -0.0160957 |
| NPR2 | natriuretic peptide receptor 2 | -0.0160774 |
| NEMF | nuclear export mediator factor | -0.0160073 |
| HM13 | histocompatibility (minor) 13 | -0.0159754 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0156886 |
| COMMD10 | COMM domain containing 10 | -0.0155251 |
| FAM3C | family with sequence similarity 3, member C | -0.0154742 |
| GNPNAT1 | glucosamine-phosphate N-acetyltransferase 1 | -0.0153529 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.0152954 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0152175 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0151425 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0150604 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0150572 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | -0.0150155 |
| DSG2 | desmoglein 2 | -0.014976 |
| TRAM1 | translocation associated membrane protein 1 | -0.0149278 |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | -0.0149184 |
| RACK1 | receptor for activated C kinase 1 | -0.0148859 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.014878 |
| RPLP0 | ribosomal protein, large, P0 | -0.0147935 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0147404 |
