| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.140056 |
| SYT1 | synaptotagmin I | 0.113291 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.111347 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0916047 |
| RPS6 | ribosomal protein S6 | 0.0823073 |
| TNS3 | tensin 3 | 0.078761 |
| ATXN1 | ataxin 1 | 0.0754027 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0723316 |
| EGR1 | early growth response 1 | 0.0714021 |
| MT2A | metallothionein 2A | 0.0666478 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0645018 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0610838 |
| WWOX | WW domain containing oxidoreductase | 0.0604661 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0604357 |
| EZR | ezrin | 0.0602022 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0581354 |
| YAP1 | Yes-associated protein 1 | 0.0538724 |
| RPL35A | ribosomal protein L35a | 0.0527676 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0518497 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0513174 |
| BCL2L1 | BCL2-like 1 | 0.0512567 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0491856 |
| LMO7 | LIM domain 7 | 0.048207 |
| SMAD3 | SMAD family member 3 | 0.0474724 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0473254 |
| RPS19 | ribosomal protein S19 | 0.0467541 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0450651 |
| SVIL | supervillin | 0.044477 |
| POTEF | POTE ankyrin domain family, member F | 0.0440818 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0431343 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0430229 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0414912 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0407626 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.040484 |
| CENPF | centromere protein F, 350/400kDa | 0.0397571 |
| RUNX1 | runt-related transcription factor 1 | 0.0395291 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0395152 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.03946 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0390704 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0387283 |
| RPL11 | ribosomal protein L11 | 0.038319 |
| JMJD1C | jumonji domain containing 1C | 0.0382496 |
| MSN | moesin | 0.0381562 |
| PCM1 | pericentriolar material 1 | 0.0372194 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0371462 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0360664 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0360184 |
| MSI2 | musashi RNA-binding protein 2 | 0.0354889 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0352079 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0350046 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0346643 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0340755 |
| RNF43 | ring finger protein 43 | 0.0339103 |
| ZNRF3 | zinc and ring finger 3 | 0.0336146 |
| DOCK4 | dedicator of cytokinesis 4 | 0.033564 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.0335507 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0333428 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0323169 |
| VMP1 | vacuole membrane protein 1 | 0.0322739 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0322454 |
| MKI67 | marker of proliferation Ki-67 | 0.0313364 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0309408 |
| TJP1 | tight junction protein 1 | 0.0308469 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0307955 |
| RPL27 | ribosomal protein L27 | 0.0307753 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0307161 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0306757 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0306415 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0305119 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0304774 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0302642 |
| COBL | cordon-bleu WH2 repeat protein | 0.0301595 |
| TNS4 | tensin 4 | 0.0297787 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0296797 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0295886 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0291614 |
| RPL19 | ribosomal protein L19 | 0.029108 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0288294 |
| FOSL1 | FOS-like antigen 1 | 0.0287413 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0284225 |
| BMP5 | bone morphogenetic protein 5 | 0.0283383 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0282113 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0279831 |
| GPHN | gephyrin | 0.0275784 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0271878 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0271404 |
| FRMD5 | FERM domain containing 5 | 0.0271062 |
| RPL21 | ribosomal protein L21 | 0.0270001 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0268499 |
| MYO10 | myosin X | 0.0268417 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0268188 |
| EFNB2 | ephrin-B2 | 0.0267292 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0266644 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0265603 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0264678 |
| NEBL | nebulette | 0.0264409 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.026406 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0263528 |
| PRKCA | protein kinase C, alpha | 0.0262444 |
| SLTM | SAFB-like, transcription modulator | 0.0261462 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.13468 |
| AHNAK | AHNAK nucleoprotein | -0.12711 |
| RPS27A | ribosomal protein S27a | -0.113208 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.112632 |
| PTMA | prothymosin, alpha | -0.112394 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109546 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100366 |
| CCND1 | cyclin D1 | -0.0985306 |
| UBC | ubiquitin C | -0.0964892 |
| CDH13 | cadherin 13 | -0.0957544 |
| CANX | calnexin | -0.0946364 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0909002 |
| KRT18 | keratin 18, type I | -0.0873187 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0817108 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0816211 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0810687 |
| ENO1 | enolase 1, (alpha) | -0.0770679 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0735467 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0732845 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0690971 |
| RPS24 | ribosomal protein S24 | -0.0642017 |
| LDHA | lactate dehydrogenase A | -0.0585471 |
| KRT8 | keratin 8, type II | -0.0512735 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0505499 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0499122 |
| INTS6 | integrator complex subunit 6 | -0.0467812 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0438897 |
| EPCAM | epithelial cell adhesion molecule | -0.0419986 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0410666 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0393306 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0382191 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0374969 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0369291 |
| TMSB4X | thymosin beta 4, X-linked | -0.0364581 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0358525 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0354178 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0342845 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0340114 |
| CALR | calreticulin | -0.0338344 |
| VIM | vimentin | -0.0331044 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0329878 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0328584 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0328342 |
| PERP | PERP, TP53 apoptosis effector | -0.032452 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0319926 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0310071 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0309153 |
| GLG1 | golgi glycoprotein 1 | -0.0307809 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0302655 |
| TMSB10 | thymosin beta 10 | -0.0302092 |
| ITGB4 | integrin, beta 4 | -0.0296534 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0292896 |
| PKM | pyruvate kinase, muscle | -0.0289186 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0288207 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0286682 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0284329 |
| FLNB | filamin B, beta | -0.0282029 |
| TFRC | transferrin receptor | -0.0279314 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0275211 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0272122 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.027094 |
| RPL23 | ribosomal protein L23 | -0.0270161 |
| ATM | ATM serine/threonine kinase | -0.0269319 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0265494 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0263702 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0261453 |
| AEBP2 | AE binding protein 2 | -0.0261223 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.026055 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0258971 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0256902 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0250903 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0239923 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0239737 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0239124 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0238523 |
| KRT5 | keratin 5, type II | -0.0238486 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0237873 |
| TMEM123 | transmembrane protein 123 | -0.0235605 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0235354 |
| RPL4 | ribosomal protein L4 | -0.0230996 |
| OGA | O-GlcNAcase | -0.0230935 |
| IER3 | immediate early response 3 | -0.0230385 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0228623 |
| TPM4 | tropomyosin 4 | -0.0227538 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.02222 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0222095 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.021895 |
| ABLIM1 | actin binding LIM protein 1 | -0.0216672 |
| ANLN | anillin, actin binding protein | -0.0214245 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0214104 |
| KHSRP | KH-type splicing regulatory protein | -0.0211891 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.02115 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0209424 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0208212 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0207749 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0206074 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0201132 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | -0.0200407 |
| SET | SET nuclear proto-oncogene | -0.0199541 |
| CBX5 | chromobox homolog 5 | -0.0199394 |
