| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.208085 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.101797 |
| GLIS3 | GLIS family zinc finger 3 | 0.0898134 |
| ASPH | aspartate beta-hydroxylase | 0.0877024 |
| NAV1 | neuron navigator 1 | 0.0862057 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0857443 |
| SMAD3 | SMAD family member 3 | 0.0843401 |
| COL1A1 | collagen, type I, alpha 1 | 0.0812868 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0802102 |
| FRMD4A | FERM domain containing 4A | 0.0787148 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0782695 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.078004 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0716778 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.067539 |
| MYO10 | myosin X | 0.0591043 |
| RUNX1 | runt-related transcription factor 1 | 0.0581265 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0580082 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0573319 |
| POTEF | POTE ankyrin domain family, member F | 0.057197 |
| INHBA | inhibin, beta A | 0.0544466 |
| CALD1 | caldesmon 1 | 0.0543961 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0541364 |
| ACTG1 | actin gamma 1 | 0.0530762 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0502376 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0495505 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0491041 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0484227 |
| HLA-B | major histocompatibility complex, class I, B | 0.0481657 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.04728 |
| MAP1B | microtubule-associated protein 1B | 0.0471207 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0470261 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0469996 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0468572 |
| MSN | moesin | 0.0461782 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0459689 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0444031 |
| VCL | vinculin | 0.044336 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0442999 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0439625 |
| EGFR | epidermal growth factor receptor | 0.0432716 |
| DST | dystonin | 0.0418516 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0414364 |
| JMJD1C | jumonji domain containing 1C | 0.0399187 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0394818 |
| NOTCH2 | notch 2 | 0.0384889 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0384666 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.038148 |
| INTS6 | integrator complex subunit 6 | 0.0377545 |
| SEPTIN11 | septin 11 | 0.0377344 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0366349 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0354731 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0352534 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0348051 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0344341 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0344199 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0341709 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0333559 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0333211 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0328414 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0326355 |
| NUMB | numb homolog (Drosophila) | 0.0325545 |
| PARD3 | par-3 family cell polarity regulator | 0.0321829 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0320956 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0318772 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0317623 |
| PTK2 | protein tyrosine kinase 2 | 0.0316776 |
| FLNA | filamin A, alpha | 0.0315975 |
| VEGFC | vascular endothelial growth factor C | 0.031573 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0315551 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0310703 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0304931 |
| FOXP1 | forkhead box P1 | 0.0301073 |
| ACTN1 | actinin, alpha 1 | 0.0300422 |
| FSTL1 | follistatin-like 1 | 0.0293158 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0292747 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0290941 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0289691 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0288735 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0285997 |
| CDK6 | cyclin-dependent kinase 6 | 0.0280446 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0278583 |
| CD44 | CD44 molecule (Indian blood group) | 0.0276941 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0273794 |
| RPL23 | ribosomal protein L23 | 0.0272788 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0271646 |
| CLIC4 | chloride intracellular channel 4 | 0.0270872 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0270819 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0270762 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0269963 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0269908 |
| NABP1 | nucleic acid binding protein 1 | 0.0269416 |
| SEPTIN9 | septin 9 | 0.0268329 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0267932 |
| NCKAP1 | NCK-associated protein 1 | 0.0267175 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0266612 |
| ERBIN | erbb2 interacting protein | 0.026637 |
| KLF12 | Kruppel-like factor 12 | 0.0265942 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0263788 |
| FLNB | filamin B, beta | 0.0263138 |
| TPM1 | tropomyosin 1 (alpha) | 0.0263036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.230973 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.154506 |
| VIM | vimentin | -0.153593 |
| MMP1 | matrix metallopeptidase 1 | -0.111093 |
| OXR1 | oxidation resistance 1 | -0.0789806 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0749729 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0738943 |
| MMP12 | matrix metallopeptidase 12 | -0.0721629 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0614048 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0567227 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0539929 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0454793 |
| STC1 | stanniocalcin 1 | -0.0452751 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0450557 |
| EMP1 | epithelial membrane protein 1 | -0.0421472 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0418524 |
| LMAN1 | lectin, mannose-binding, 1 | -0.040833 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0385582 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0368361 |
| AHNAK | AHNAK nucleoprotein | -0.0364752 |
| NGLY1 | N-glycanase 1 | -0.034076 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0339119 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0327968 |
| NDRG1 | N-myc downstream regulated 1 | -0.0327723 |
| CAVIN1 | caveolae associated protein 1 | -0.0324219 |
| TMSB10 | thymosin beta 10 | -0.0319282 |
| HLA-E | major histocompatibility complex, class I, E | -0.031207 |
| COL3A1 | collagen, type III, alpha 1 | -0.0299232 |
| FMNL2 | formin-like 2 | -0.0290079 |
| TPM4 | tropomyosin 4 | -0.0288131 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0286897 |
| CANX | calnexin | -0.0276735 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.027588 |
| PRRX1 | paired related homeobox 1 | -0.027502 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0265457 |
| INSIG1 | insulin induced gene 1 | -0.0261504 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0258601 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0255729 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0243221 |
| CA12 | carbonic anhydrase XII | -0.0241509 |
| NCKAP5 | NCK-associated protein 5 | -0.0234682 |
| ITGA1 | integrin, alpha 1 | -0.0233092 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0231672 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0230137 |
| S100A6 | S100 calcium binding protein A6 | -0.0230042 |
| FTL | ferritin, light polypeptide | -0.022507 |
| RPL34 | ribosomal protein L34 | -0.0219346 |
| FRMD6 | FERM domain containing 6 | -0.021818 |
| TMEM165 | transmembrane protein 165 | -0.0214779 |
| SRP54 | signal recognition particle 54kDa | -0.0212866 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0211516 |
| PRDM1 | PR domain containing 1, with ZNF domain | -0.0207577 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0206053 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.020367 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0196995 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.019438 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0194281 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0192507 |
| GK | glycerol kinase | -0.019188 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0187458 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.0179594 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0174636 |
| HLA-C | major histocompatibility complex, class I, C | -0.017435 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0172823 |
| PCDH9 | protocadherin 9 | -0.0172567 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.0171139 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0170154 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0169796 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0167377 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.016231 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0162095 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0161697 |
| RPL4 | ribosomal protein L4 | -0.0161152 |
| HM13 | histocompatibility (minor) 13 | -0.0160174 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0159998 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0158876 |
| WDR45B | WD repeat domain 45B | -0.0154818 |
| PGK1 | phosphoglycerate kinase 1 | -0.0150975 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0150867 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0150517 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0149925 |
| PTMA | prothymosin, alpha | -0.0149224 |
| GOLT1B | golgi transport 1B | -0.0148738 |
| THBS2 | thrombospondin 2 | -0.0148112 |
| RPL35A | ribosomal protein L35a | -0.0148108 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0146928 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0145658 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0145283 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0142606 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0141811 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.014175 |
| RND3 | Rho family GTPase 3 | -0.0141098 |
| DNER | delta/notch-like EGF repeat containing | -0.0140138 |
| LAMA4 | laminin, alpha 4 | -0.0139962 |
| HDLBP | high density lipoprotein binding protein | -0.0139872 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0139074 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0138169 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0137749 |
| IPO5 | importin 5 | -0.0137244 |
| RHOQ | ras homolog family member Q | -0.0135592 |
