| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0717318 |
| NHSL1 | NHS-like 1 | 0.0476885 |
| PCBP2 | poly(rC) binding protein 2 | 0.0469225 |
| CCNL1 | cyclin L1 | 0.045707 |
| RRM2 | ribonucleotide reductase M2 | 0.043252 |
| TPM3 | tropomyosin 3 | 0.0427496 |
| HELLS | helicase, lymphoid-specific | 0.0411851 |
| ASPH | aspartate beta-hydroxylase | 0.0409161 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0395493 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0383024 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0382093 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0355575 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0326477 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0291414 |
| DIAPH3 | diaphanous-related formin 3 | 0.0290671 |
| RTN4 | reticulon 4 | 0.0286137 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0285401 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0282094 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0279 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0270048 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0267914 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0265939 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0263831 |
| MEMO1 | mediator of cell motility 1 | 0.0258427 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0258274 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0251192 |
| YAP1 | Yes-associated protein 1 | 0.024337 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0239726 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0239551 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0238877 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0236947 |
| WDR43 | WD repeat domain 43 | 0.0232844 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0232479 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0228265 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0227327 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0224319 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0222954 |
| CLDND1 | claudin domain containing 1 | 0.0221393 |
| GPHN | gephyrin | 0.0221374 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0221033 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0220799 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0219948 |
| INTS6 | integrator complex subunit 6 | 0.0216937 |
| GASK1B | golgi associated kinase 1B | 0.0216564 |
| RPS12 | ribosomal protein S12 | 0.0214376 |
| DENND5A | DENN/MADD domain containing 5A | 0.0214027 |
| TFG | TRK-fused gene | 0.0213836 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0212257 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0212031 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0209113 |
| ARRDC3 | arrestin domain containing 3 | 0.020558 |
| JMJD1C | jumonji domain containing 1C | 0.0205066 |
| RCOR1 | REST corepressor 1 | 0.0204616 |
| VCL | vinculin | 0.0202408 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0199352 |
| NUP58 | nucleoporin 58 | 0.0196629 |
| RBM33 | RNA binding motif protein 33 | 0.0196131 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.019533 |
| PCDH9 | protocadherin 9 | 0.0192581 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0192371 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0192288 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0189517 |
| NBAS | neuroblastoma amplified sequence | 0.0189337 |
| ACTG1 | actin gamma 1 | 0.0186571 |
| CEP95 | centrosomal protein 95kDa | 0.0185293 |
| RPL37A | ribosomal protein L37a | 0.0183073 |
| RAD51B | RAD51 paralog B | 0.0181427 |
| NEGR1 | neuronal growth regulator 1 | 0.0180592 |
| PCM1 | pericentriolar material 1 | 0.0178863 |
| ETNK1 | ethanolamine kinase 1 | 0.0178353 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0178205 |
| ATP13A3 | ATPase type 13A3 | 0.0177955 |
| E2F7 | E2F transcription factor 7 | 0.0173575 |
| MCL1 | myeloid cell leukemia 1 | 0.0171555 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV | 0.0171273 |
| CPOX | coproporphyrinogen oxidase | 0.0168784 |
| MSH6 | mutS homolog 6 | 0.0167332 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.016668 |
| MEF2A | myocyte enhancer factor 2A | 0.016662 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.016661 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0165333 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0164881 |
| RPL3 | ribosomal protein L3 | 0.0164829 |
| MYO19 | myosin XIX | 0.016463 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0163296 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0160952 |
| HHAT | hedgehog acyltransferase | 0.0160934 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0160292 |
| POTEF | POTE ankyrin domain family, member F | 0.0160007 |
| RNF13 | ring finger protein 13 | 0.0159943 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0159662 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0158779 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0158742 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0158317 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0158196 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.0157791 |
| WDHD1 | WD repeat and HMG-box DNA binding protein 1 | 0.015742 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0156845 |
| FAM111B | family with sequence similarity 111, member B | 0.0156387 |
| MSH2 | mutS homolog 2 | 0.0155123 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.325165 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.166887 |
| NLGN1 | neuroligin 1 | -0.163587 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.158953 |
| AREG | amphiregulin | -0.154945 |
| TMSB10 | thymosin beta 10 | -0.134005 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.109919 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.104781 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0873763 |
| PCDH7 | protocadherin 7 | -0.0769589 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0758939 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0712254 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0698232 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0696504 |
| ANXA1 | annexin A1 | -0.0662235 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0642922 |
| H1-0 | H1.0 linker histone | -0.0632432 |
| CCND1 | cyclin D1 | -0.0631012 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0622969 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0615427 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0513661 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0498709 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0491055 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0489302 |
| AHNAK | AHNAK nucleoprotein | -0.0484988 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0471145 |
| RPLP1 | ribosomal protein, large, P1 | -0.0469496 |
| EDN1 | endothelin 1 | -0.0462516 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0457128 |
| TPI1 | triosephosphate isomerase 1 | -0.0454172 |
| FTL | ferritin, light polypeptide | -0.0449038 |
| YBX3 | Y box binding protein 3 | -0.0443313 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0438983 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0425024 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0422609 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0405581 |
| CLDN1 | claudin 1 | -0.0405425 |
| KLF6 | Kruppel-like factor 6 | -0.040041 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0381091 |
| KIF5B | kinesin family member 5B | -0.0377265 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0371799 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0370221 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0369172 |
| CENPF | centromere protein F, 350/400kDa | -0.0361262 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0355037 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0353179 |
| RPL8 | ribosomal protein L8 | -0.0347635 |
| RACK1 | receptor for activated C kinase 1 | -0.0347227 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0346883 |
| PFN1 | profilin 1 | -0.0331226 |
| RPS24 | ribosomal protein S24 | -0.0320046 |
| CDK6 | cyclin-dependent kinase 6 | -0.0317048 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0314335 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0311004 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0309743 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0309533 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0298003 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0297947 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0295166 |
| CENPE | centromere protein E, 312kDa | -0.0291693 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0286894 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0283436 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0282055 |
| TUBB | tubulin, beta class I | -0.0281873 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0280081 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0278728 |
| NPR2 | natriuretic peptide receptor 2 | -0.0274557 |
| RPL12 | ribosomal protein L12 | -0.0271031 |
| ATP11A | ATPase, class VI, type 11A | -0.0270896 |
| MKI67 | marker of proliferation Ki-67 | -0.0270624 |
| CCDC88A | coiled-coil domain containing 88A | -0.0270596 |
| CAVIN1 | caveolae associated protein 1 | -0.0265864 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0264357 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0260428 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0254408 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0253495 |
| GCG | glucagon | -0.0253101 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0252312 |
| RPS19 | ribosomal protein S19 | -0.0251438 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0251219 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0247156 |
| MPG | N-methylpurine-DNA glycosylase | -0.0244786 |
| MMP12 | matrix metallopeptidase 12 | -0.0241682 |
| RPL36 | ribosomal protein L36 | -0.0241493 |
| PEG10 | paternally expressed 10 | -0.024103 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0240449 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0239445 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0239243 |
| RPL32 | ribosomal protein L32 | -0.0235306 |
| CBX3 | chromobox homolog 3 | -0.0231342 |
| RPLP0 | ribosomal protein, large, P0 | -0.0231061 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0230138 |
| RPLP2 | ribosomal protein, large, P2 | -0.0229557 |
| TMEM123 | transmembrane protein 123 | -0.0226017 |
| LMO7 | LIM domain 7 | -0.0223548 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0222605 |
| PGK1 | phosphoglycerate kinase 1 | -0.0221882 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0221622 |
| CCNI | cyclin I | -0.0220932 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0215904 |
