| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.121619 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.110807 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.100895 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0982708 |
| ZNF292 | zinc finger protein 292 | 0.0942161 |
| OGA | O-GlcNAcase | 0.0736156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0734969 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0651369 |
| CALR | calreticulin | 0.0645222 |
| SUCO | SUN domain containing ossification factor | 0.060968 |
| TMSB4X | thymosin beta 4, X-linked | 0.0597472 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.057991 |
| CANX | calnexin | 0.057888 |
| PCBP2 | poly(rC) binding protein 2 | 0.0558621 |
| ITGAV | integrin, alpha V | 0.0551869 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0535872 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.051889 |
| SET | SET nuclear proto-oncogene | 0.0514263 |
| GSE1 | Gse1 coiled-coil protein | 0.0506143 |
| COL1A2 | collagen, type I, alpha 2 | 0.0495994 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.049525 |
| GOLGA4 | golgin A4 | 0.0489625 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0487057 |
| B2M | beta-2-microglobulin | 0.0482854 |
| HELLS | helicase, lymphoid-specific | 0.0478768 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0476243 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0463242 |
| QKI | QKI, KH domain containing, RNA binding | 0.0456974 |
| MED13L | mediator complex subunit 13-like | 0.0454413 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0450546 |
| ENO1 | enolase 1, (alpha) | 0.0449007 |
| MED14 | mediator complex subunit 14 | 0.0445488 |
| UTRN | utrophin | 0.0443455 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0439028 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.043403 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0433468 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0420739 |
| VCL | vinculin | 0.0414976 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0413612 |
| MATR3 | matrin 3 | 0.0410035 |
| CCNL1 | cyclin L1 | 0.0409064 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0407422 |
| PRRC2C | proline-rich coiled-coil 2C | 0.04051 |
| RNF145 | ring finger protein 145 | 0.0401493 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.039871 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0398638 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0397949 |
| FKBP5 | FK506 binding protein 5 | 0.0396066 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0395228 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0389758 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0386424 |
| RAD51B | RAD51 paralog B | 0.0385003 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0381252 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0371965 |
| RLF | rearranged L-myc fusion | 0.0368103 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0366915 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.035991 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.035504 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0346278 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0343099 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0338447 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0337857 |
| TPM3 | tropomyosin 3 | 0.0335872 |
| MEST | mesoderm specific transcript | 0.0335831 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0334833 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0333731 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0331328 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0329691 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0328662 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0327938 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0326858 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0321562 |
| USP3 | ubiquitin specific peptidase 3 | 0.0321036 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0319073 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0318207 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0315574 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0314965 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.031437 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0312815 |
| KAZN | kazrin, periplakin interacting protein | 0.0311106 |
| SEPTIN7 | septin 7 | 0.0310483 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0310148 |
| ETNK1 | ethanolamine kinase 1 | 0.0310061 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0308419 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0308284 |
| KLHDC10 | kelch domain containing 10 | 0.030793 |
| SPAG9 | sperm associated antigen 9 | 0.0306706 |
| RPS4X | ribosomal protein S4, X-linked | 0.030669 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0306271 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0306057 |
| YBX1 | Y box binding protein 1 | 0.0304814 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0304657 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0304419 |
| FANCI | Fanconi anemia, complementation group I | 0.0303921 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0303619 |
| SFTPA2 | surfactant protein A2 | 0.0301144 |
| APP | amyloid beta (A4) precursor protein | 0.0300496 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0299707 |
| SYAP1 | synapse associated protein 1 | 0.0299218 |
| TBK1 | TANK-binding kinase 1 | 0.0298152 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.226615 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.215201 |
| VIM | vimentin | -0.214867 |
| HMGA2 | high mobility group AT-hook 2 | -0.163771 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.120065 |
| PEG10 | paternally expressed 10 | -0.0973442 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.093051 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.081136 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0756177 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0735955 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0702991 |
| CTBP2 | C-terminal binding protein 2 | -0.056954 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0567055 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0473075 |
| TMSB10 | thymosin beta 10 | -0.0469912 |
| RPS24 | ribosomal protein S24 | -0.0465454 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0460663 |
| MYOF | myoferlin | -0.045845 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0424157 |
| ZFHX3 | zinc finger homeobox 3 | -0.0400581 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.038226 |
| FLNB | filamin B, beta | -0.0381545 |
| RPS23 | ribosomal protein S23 | -0.0375138 |
| CENPE | centromere protein E, 312kDa | -0.037155 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0359141 |
| CENPF | centromere protein F, 350/400kDa | -0.035535 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0354719 |
| INTS6 | integrator complex subunit 6 | -0.0352095 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0351282 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0350116 |
| HMGA1 | high mobility group AT-hook 1 | -0.0342279 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0335158 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0316956 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0314794 |
| TRIM9 | tripartite motif containing 9 | -0.0309754 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0309502 |
| FBXO11 | F-box protein 11 | -0.03007 |
| RPL31 | ribosomal protein L31 | -0.0293002 |
| RPL37A | ribosomal protein L37a | -0.0291733 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.029162 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0280874 |
| PRLR | prolactin receptor | -0.0278973 |
| ANO6 | anoctamin 6 | -0.0277832 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0277717 |
| NBEA | neurobeachin | -0.0277195 |
| DENND1A | DENN/MADD domain containing 1A | -0.0276955 |
| COMMD10 | COMM domain containing 10 | -0.0272556 |
| FOXP1 | forkhead box P1 | -0.0270169 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0267637 |
| RPL28 | ribosomal protein L28 | -0.0266883 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0266596 |
| CREBBP | CREB binding protein | -0.0264237 |
| MEIS2 | Meis homeobox 2 | -0.0263503 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.026109 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0259055 |
| CUX1 | cut-like homeobox 1 | -0.0258958 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0256797 |
| TCF12 | transcription factor 12 | -0.0251182 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.02487 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0248183 |
| IER3 | immediate early response 3 | -0.0244608 |
| PDE10A | phosphodiesterase 10A | -0.0244328 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0243895 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0240248 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0236678 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0236354 |
| EGFR | epidermal growth factor receptor | -0.0233985 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0233312 |
| RPS29 | ribosomal protein S29 | -0.0227062 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0225198 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0222395 |
| TULP4 | tubby like protein 4 | -0.0221306 |
| ATN1 | atrophin 1 | -0.0221001 |
| EGR1 | early growth response 1 | -0.0220587 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0220525 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0217496 |
| TFRC | transferrin receptor | -0.0215732 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0215507 |
| NPR2 | natriuretic peptide receptor 2 | -0.021434 |
| FLNA | filamin A, alpha | -0.0210773 |
| RPL34 | ribosomal protein L34 | -0.0210007 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | -0.0207408 |
| RPS27A | ribosomal protein S27a | -0.0206488 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0205323 |
| MTDH | metadherin | -0.0203369 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0202831 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0200878 |
| NRF1 | nuclear respiratory factor 1 | -0.0199876 |
| CREM | cAMP responsive element modulator | -0.0199039 |
| DEPDC1B | DEP domain containing 1B | -0.019822 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0198065 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0197492 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0196533 |
| RAI1 | retinoic acid induced 1 | -0.0196191 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0195353 |
| FAM193A | family with sequence similarity 193, member A | -0.019496 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0192795 |
| LRRC23 | leucine rich repeat containing 23 | -0.0192571 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0192463 |
| RCOR1 | REST corepressor 1 | -0.0191625 |
