| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.140536 |
| PTMA | prothymosin, alpha | 0.120579 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.107743 |
| VMP1 | vacuole membrane protein 1 | 0.103776 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0950686 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0933407 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0905448 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0860247 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0774353 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0717184 |
| SDC4 | syndecan 4 | 0.0711349 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0684314 |
| TPM3 | tropomyosin 3 | 0.0675263 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0644299 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0638631 |
| SET | SET nuclear proto-oncogene | 0.0610426 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0583499 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0560016 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0552708 |
| DSPP | dentin sialophosphoprotein | 0.0526486 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.051051 |
| CCNL1 | cyclin L1 | 0.0470589 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0448355 |
| ENAH | enabled homolog (Drosophila) | 0.0443743 |
| KIAA1217 | KIAA1217 | 0.044158 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0436774 |
| KAZN | kazrin, periplakin interacting protein | 0.0431803 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0429326 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0427842 |
| SHROOM3 | shroom family member 3 | 0.0424728 |
| KRT8 | keratin 8, type II | 0.0424215 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0422137 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0406528 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.039905 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0394127 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0392058 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0383887 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0383109 |
| PDLIM5 | PDZ and LIM domain 5 | 0.03765 |
| RAB6A | RAB6A, member RAS oncogene family | 0.037477 |
| TMSB4X | thymosin beta 4, X-linked | 0.0363663 |
| DUSP16 | dual specificity phosphatase 16 | 0.0360005 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0356083 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0351735 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0344269 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0338452 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0332021 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0331305 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0326496 |
| MYO6 | myosin VI | 0.0321538 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0315962 |
| MYO10 | myosin X | 0.0314049 |
| PRLR | prolactin receptor | 0.0313588 |
| AHNAK | AHNAK nucleoprotein | 0.0311588 |
| RPS3 | ribosomal protein S3 | 0.0311389 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0310907 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.030977 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0308393 |
| TMEM41B | transmembrane protein 41B | 0.0307669 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0306575 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0306202 |
| TENM2 | teneurin transmembrane protein 2 | 0.0305658 |
| RRM2 | ribonucleotide reductase M2 | 0.0304822 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0304688 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0304589 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0300247 |
| ACTG1 | actin gamma 1 | 0.029705 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0294811 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0294657 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0290764 |
| WWOX | WW domain containing oxidoreductase | 0.0290377 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0289376 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0288781 |
| USP3 | ubiquitin specific peptidase 3 | 0.0286054 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0285314 |
| DENND4A | DENN/MADD domain containing 4A | 0.0284833 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0281712 |
| KIF16B | kinesin family member 16B | 0.0279381 |
| AUTS2 | autism susceptibility candidate 2 | 0.0277853 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0273781 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0270199 |
| INSIG1 | insulin induced gene 1 | 0.0268111 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0267888 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0266599 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0261826 |
| CALR | calreticulin | 0.0261489 |
| SUCO | SUN domain containing ossification factor | 0.0257851 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0257795 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0257276 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.025663 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0256598 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0256312 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0256113 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0255451 |
| GOLGA4 | golgin A4 | 0.0249634 |
| TFRC | transferrin receptor | 0.0249254 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0247821 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0246966 |
| MED13L | mediator complex subunit 13-like | 0.0244767 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0243898 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18051 |
| TMSB10 | thymosin beta 10 | -0.0927679 |
| MT2A | metallothionein 2A | -0.0904206 |
| RPL19 | ribosomal protein L19 | -0.0876411 |
| NDRG1 | N-myc downstream regulated 1 | -0.0811342 |
| RPL23 | ribosomal protein L23 | -0.0643779 |
| S100A9 | S100 calcium binding protein A9 | -0.0566208 |
| INTS6 | integrator complex subunit 6 | -0.0542645 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0529864 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0528527 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0471597 |
| S100A8 | S100 calcium binding protein A8 | -0.047013 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0465103 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0452417 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0426676 |
| EGFR | epidermal growth factor receptor | -0.0419132 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0413973 |
| EFNA5 | ephrin-A5 | -0.0412728 |
| MMP24OS | MMP24 opposite strand | -0.0399786 |
| ANKRD12 | ankyrin repeat domain 12 | -0.039657 |
| FTL | ferritin, light polypeptide | -0.0389403 |
| RPL32 | ribosomal protein L32 | -0.0383957 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0366051 |
| SP100 | SP100 nuclear antigen | -0.035473 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0347744 |
| CCND1 | cyclin D1 | -0.0344656 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0332208 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0328611 |
| KRT86 | keratin 86, type II | -0.0308052 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0303029 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0300198 |
| AREG | amphiregulin | -0.0294225 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0282203 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0274816 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0273754 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0267082 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.026018 |
| RPL35A | ribosomal protein L35a | -0.0257268 |
| S100A11 | S100 calcium binding protein A11 | -0.0256032 |
| RPS24 | ribosomal protein S24 | -0.0253658 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0252422 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0252184 |
| S100A7 | S100 calcium binding protein A7 | -0.0250994 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0245399 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.02432 |
| RPLP1 | ribosomal protein, large, P1 | -0.023935 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.023825 |
| RPS29 | ribosomal protein S29 | -0.0238228 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0236882 |
| RPL9 | ribosomal protein L9 | -0.0236068 |
| NABP1 | nucleic acid binding protein 1 | -0.0235203 |
| OSMR | oncostatin M receptor | -0.0231547 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0229471 |
| RPL28 | ribosomal protein L28 | -0.0227876 |
| RPL35 | ribosomal protein L35 | -0.0220283 |
| S100P | S100 calcium binding protein P | -0.0217837 |
| S100A14 | S100 calcium binding protein A14 | -0.0214708 |
| SNX14 | sorting nexin 14 | -0.0213961 |
| RPL31 | ribosomal protein L31 | -0.0211405 |
| STXBP4 | syntaxin binding protein 4 | -0.0210978 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0209674 |
| LMO7 | LIM domain 7 | -0.0208014 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0206336 |
| LOXL2 | lysyl oxidase-like 2 | -0.0205628 |
| PLSCR2 | phospholipid scramblase 2 | -0.0202918 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0201415 |
| TXNRD1 | thioredoxin reductase 1 | -0.0200455 |
| VIM | vimentin | -0.0199179 |
| SYNRG | synergin, gamma | -0.0197655 |
| GLCCI1 | glucocorticoid induced 1 | -0.0197644 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0196368 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0194284 |
| PRR11 | proline rich 11 | -0.0194036 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0193583 |
| RPL5 | ribosomal protein L5 | -0.0192664 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0191351 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0188849 |
| ARMH4 | armadillo like helical domain containing 4 | -0.018772 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.018753 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0186946 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0186487 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0185766 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0185042 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.01845 |
| PLSCR1 | phospholipid scramblase 1 | -0.0184463 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | -0.0184219 |
| S100A10 | S100 calcium binding protein A10 | -0.0183797 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0182184 |
| EGR1 | early growth response 1 | -0.0181467 |
| RGS6 | regulator of G-protein signaling 6 | -0.0180228 |
| NTN4 | netrin 4 | -0.0177431 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0174588 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0173355 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0172099 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0172001 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0171603 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0171276 |
| TUBB | tubulin, beta class I | -0.0170743 |
| RPL8 | ribosomal protein L8 | -0.0168843 |
| CD44 | CD44 molecule (Indian blood group) | -0.0168841 |
