Cytarabine (hydrochloride)_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Cytarabine (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Cytarabine (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MBNL2 muscleblind-like splicing regulator 2 0.0632007
RAD51B RAD51 paralog B 0.0459734
DIAPH3 diaphanous-related formin 3 0.0389475
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0341905
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0278797
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0270921
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0264399
GRK3 G protein-coupled receptor kinase 3 0.0253462
DENND4C DENN/MADD domain containing 4C 0.0246431
SDC4 syndecan 4 0.0238756
FANCI Fanconi anemia, complementation group I 0.0235663
RNF149 ring finger protein 149 0.0227682
GOLGA2 golgin A2 0.0224724
ARRDC3 arrestin domain containing 3 0.0217306
IFNGR1 interferon gamma receptor 1 0.0216713
ZNF395 zinc finger protein 395 0.0216142
ESYT2 extended synaptotagmin-like protein 2 0.0213226
CCDC14 coiled-coil domain containing 14 0.0211809
DSCAML1 Down syndrome cell adhesion molecule like 1 0.0210289
PCSK6 proprotein convertase subtilisin/kexin type 6 0.0207728
FNIP1 folliculin interacting protein 1 0.0204762
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.0202754
BHLHE40 basic helix-loop-helix family, member e40 0.0199464
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0197156
BRCA1 breast cancer 1, early onset 0.0195623
GRAMD2B GRAM domain containing 2B 0.0192307
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0191504
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0190952
RRM2 ribonucleotide reductase M2 0.0190503
TC2N tandem C2 domains, nuclear 0.0188575
SEC24D SEC24 family member D 0.0188434
MON2 MON2 homolog (S. cerevisiae) 0.0185572
ATAD2 ATPase family, AAA domain containing 2 0.0182923
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0179677
CCNL1 cyclin L1 0.0179353
PTEN phosphatase and tensin homolog 0.0177206
DST dystonin 0.0174327
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0166445
GOLGB1 golgin B1 0.0165378
RAD54B RAD54 homolog B (S. cerevisiae) 0.0165158
CENPP centromere protein P 0.0163783
KLF5 Kruppel-like factor 5 (intestinal) 0.0163585
ARHGAP32 Rho GTPase activating protein 32 0.0163245
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0162593
KIF16B kinesin family member 16B 0.0160411
ZMYM2 zinc finger, MYM-type 2 0.0160246
RARS1 arginyl-tRNA synthetase 1 0.015959
USPL1 ubiquitin specific peptidase like 1 0.0157588
CEP152 centrosomal protein 152kDa 0.0156168
DYNC2I1 dynein 2 intermediate chain 1 0.0148857
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0148589
YEATS2 YEATS domain containing 2 0.0148319
SFXN1 sideroflexin 1 0.0147195
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0144857
BRCA2 breast cancer 2, early onset 0.0144406
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.0139731
COG6 component of oligomeric golgi complex 6 0.0139696
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.013892
PLIN2 perilipin 2 0.013691
SLC22A23 solute carrier family 22, member 23 0.0136842
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0134964
EIF4B eukaryotic translation initiation factor 4B 0.013476
STIL SCL/TAL1 interrupting locus 0.0134692
SUCO SUN domain containing ossification factor 0.0133415
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0132804
APOL2 apolipoprotein L, 2 0.0132182
MCTP2 multiple C2 domains, transmembrane 2 0.0131748
AGR2 anterior gradient 2 0.0130931
FDPS farnesyl diphosphate synthase 0.0130203
GOLGA4 golgin A4 0.0130091
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0129963
MEF2A myocyte enhancer factor 2A 0.012942
FOSL2 FOS-like antigen 2 0.01288
ANXA1 annexin A1 0.0128309
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.0124631
RLF rearranged L-myc fusion 0.0124519
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0124078
CYTH1 cytohesin 1 0.0122038
CPNE4 copine IV 0.0121867
SCAPER S-phase cyclin A-associated protein in the ER 0.0121763
TSC22D2 TSC22 domain family, member 2 0.0121658
SORBS1 sorbin and SH3 domain containing 1 0.0121458
SEC23A Sec23 homolog A (S. cerevisiae) 0.012062
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0120023
CMIP c-Maf inducing protein 0.0119168
CEP126 centrosomal protein 126kDa 0.0118978
KMT2E lysine (K)-specific methyltransferase 2E 0.0117973
TMEM39A transmembrane protein 39A 0.0117474
NEBL nebulette 0.0116999
ATAD5 ATPase family, AAA domain containing 5 0.0116571
DNM2 dynamin 2 0.0115827
USP47 ubiquitin specific peptidase 47 0.0115771
SPICE1 spindle and centriole associated protein 1 0.0115206
FAM13A family with sequence similarity 13, member A 0.0115103
AFF1 AF4/FMR2 family, member 1 0.011492
RAB6A RAB6A, member RAS oncogene family 0.0114915
UBE2O ubiquitin-conjugating enzyme E2O 0.0114839
MXI1 MAX interactor 1, dimerization protein 0.0114489
HELZ helicase with zinc finger 0.0113953
ZNF160 zinc finger protein 160 0.0113875

decreased expression

Symbol Name Standardized Value
UBC ubiquitin C -0.202059
PKM pyruvate kinase, muscle -0.110868
RNF213 ring finger protein 213 -0.110722
EPSTI1 epithelial stromal interaction 1 (breast) -0.106943
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.104255
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.103135
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0991463
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.0961098
PERP PERP, TP53 apoptosis effector -0.0937263
C6ORF132 chromosome 6 open reading frame 132 -0.0920938
LMO7 LIM domain 7 -0.0886049
LCN2 lipocalin 2 -0.0856564
MX2 MX dynamin-like GTPase 2 -0.0853278
JUN jun proto-oncogene -0.0839637
SP100 SP100 nuclear antigen -0.0816997
TPT1 tumor protein, translationally-controlled 1 -0.0788596
ANXA2 annexin A2 -0.0770184
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0724018
MX1 MX dynamin-like GTPase 1 -0.0673812
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0640519
B2M beta-2-microglobulin -0.0636771
RIGI RNA sensor RIG-I -0.0629401
ITGA6 integrin, alpha 6 -0.0628364
EPHB2 EPH receptor B2 -0.0610098
IFI6 interferon, alpha-inducible protein 6 -0.0598066
PLSCR1 phospholipid scramblase 1 -0.0597079
EPCAM epithelial cell adhesion molecule -0.0578417
VMP1 vacuole membrane protein 1 -0.0560753
LOC102724023 ES1 protein homolog, mitochondrial -0.0555078
EZR ezrin -0.0545085
TMSB10 thymosin beta 10 -0.0540706
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.05397
PTMA prothymosin, alpha -0.0530898
PDIA3 protein disulfide isomerase family A, member 3 -0.052661
ACTN4 actinin, alpha 4 -0.0522626
STS steroid sulfatase (microsomal), isozyme S -0.0515594
AKAP13 A kinase (PRKA) anchor protein 13 -0.050692
LYZ lysozyme -0.0501347
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0486497
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0484287
ARHGAP26 Rho GTPase activating protein 26 -0.0467755
ENO1 enolase 1, (alpha) -0.046764
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0462615
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0462245
RAB7A RAB7A, member RAS oncogene family -0.0455479
TXNIP thioredoxin interacting protein -0.0455204
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0449855
TJP1 tight junction protein 1 -0.0446326
MACC1 metastasis associated in colon cancer 1 -0.0443809
EGR1 early growth response 1 -0.0443592
MSI2 musashi RNA-binding protein 2 -0.0437706
RPL23 ribosomal protein L23 -0.0433306
SPATA13 spermatogenesis associated 13 -0.0426114
MYO1E myosin IE -0.0422979
RPL7L1 ribosomal protein L7-like 1 -0.0420408
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -0.0417035
PRKCA protein kinase C, alpha -0.0412358
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0403874
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0401776
VCL vinculin -0.0401094
TM4SF1 transmembrane 4 L six family member 1 -0.0398735
TMC5 transmembrane channel-like 5 -0.0397226
MAP7 microtubule-associated protein 7 -0.038828
AHNAK AHNAK nucleoprotein -0.038654
FTL ferritin, light polypeptide -0.0378008
ERBIN erbb2 interacting protein -0.0372479
TSC22D1 TSC22 domain family, member 1 -0.0370742
AREG amphiregulin -0.0370157
MLPH melanophilin -0.036964
RUNX1 runt-related transcription factor 1 -0.0363292
RSAD2 radical S-adenosyl methionine domain containing 2 -0.0362406
ATP11A ATPase, class VI, type 11A -0.0357515
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0356203
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.0347629
EEF2 eukaryotic translation elongation factor 2 -0.0344825
RABGAP1L RAB GTPase activating protein 1-like -0.033705
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0335239
RPS27A ribosomal protein S27a -0.0334138
RRBP1 ribosome binding protein 1 -0.033248
ETV6 ets variant 6 -0.0325559
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0323203
BCL2L1 BCL2-like 1 -0.0321717
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.031581
FAT1 FAT atypical cadherin 1 -0.0313923
TSHZ2 teashirt zinc finger homeobox 2 -0.0313331
GCLC glutamate-cysteine ligase, catalytic subunit -0.0313261
IFI27 interferon, alpha-inducible protein 27 -0.0313035
SQSTM1 sequestosome 1 -0.0311942
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0311773
SOX9 SRY (sex determining region Y)-box 9 -0.0310552
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0307173
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0306217
TRIM2 tripartite motif containing 2 -0.0300839
IFIH1 interferon induced with helicase C domain 1 -0.0298615
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0293024
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.0287075
IRS2 insulin receptor substrate 2 -0.0286605
STK24 serine/threonine kinase 24 -0.0286066
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0285849
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.028479