| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.208607 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.10199 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0870948 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0798657 |
| GDF15 | growth differentiation factor 15 | 0.0723589 |
| FAM13A | family with sequence similarity 13, member A | 0.0695291 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.061858 |
| CADM1 | cell adhesion molecule 1 | 0.0615617 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0537695 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0529817 |
| STK17A | serine/threonine kinase 17a | 0.048673 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0483916 |
| NAV2 | neuron navigator 2 | 0.0398923 |
| ZNF292 | zinc finger protein 292 | 0.0392673 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0374238 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0353089 |
| OGA | O-GlcNAcase | 0.0352745 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0349961 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0346887 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0339598 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0338006 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0337008 |
| ANLN | anillin, actin binding protein | 0.0334323 |
| ENO1 | enolase 1, (alpha) | 0.0332106 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0331126 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0329294 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0327769 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0326239 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0319127 |
| TRIM22 | tripartite motif containing 22 | 0.0312215 |
| TNS3 | tensin 3 | 0.0305939 |
| APP | amyloid beta (A4) precursor protein | 0.0297023 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0296923 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0295396 |
| CANX | calnexin | 0.0289632 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0288864 |
| FAT1 | FAT atypical cadherin 1 | 0.0277941 |
| HELZ | helicase with zinc finger | 0.0276125 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0274487 |
| PHF21A | PHD finger protein 21A | 0.0274388 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0274269 |
| CD44 | CD44 molecule (Indian blood group) | 0.0273195 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0270437 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0270362 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0268509 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0267999 |
| CD109 | CD109 molecule | 0.0266159 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0264977 |
| USP3 | ubiquitin specific peptidase 3 | 0.0263157 |
| PTCHD4 | patched domain containing 4 | 0.0262998 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.026251 |
| EGFR | epidermal growth factor receptor | 0.0261436 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0260956 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0259221 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0256455 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0256098 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0254877 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0253237 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0253053 |
| GPHN | gephyrin | 0.0252024 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0251513 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0250696 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0238454 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0237304 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0237299 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0236666 |
| RLF | rearranged L-myc fusion | 0.0230601 |
| RNF213 | ring finger protein 213 | 0.0225583 |
| MEF2A | myocyte enhancer factor 2A | 0.0222184 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0222024 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0221713 |
| NCKAP1 | NCK-associated protein 1 | 0.0220792 |
| ANXA5 | annexin A5 | 0.0220332 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0219825 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.021753 |
| RUNX1 | runt-related transcription factor 1 | 0.0216455 |
| ARRDC3 | arrestin domain containing 3 | 0.0213117 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0212934 |
| MYLK | myosin light chain kinase | 0.0211797 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0206812 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0205592 |
| NLGN1 | neuroligin 1 | 0.0205051 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0204843 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0204304 |
| INHBA | inhibin, beta A | 0.0203862 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0201624 |
| E2F7 | E2F transcription factor 7 | 0.0200854 |
| SMAD3 | SMAD family member 3 | 0.0200326 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0200058 |
| CCDC14 | coiled-coil domain containing 14 | 0.0198989 |
| RIOK3 | RIO kinase 3 | 0.0197727 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0197619 |
| THBS1 | thrombospondin 1 | 0.0196016 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0195617 |
| MMP12 | matrix metallopeptidase 12 | 0.0194183 |
| WDR41 | WD repeat domain 41 | 0.0192376 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0192337 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0191126 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0189718 |
| NEK7 | NIMA-related kinase 7 | 0.0189707 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.25816 |
| MT2A | metallothionein 2A | -0.151836 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.142778 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.122988 |
| TMSB10 | thymosin beta 10 | -0.117325 |
| VIM | vimentin | -0.112451 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0957199 |
| FTL | ferritin, light polypeptide | -0.0820596 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0717765 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0692457 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0585276 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0559517 |
| EGR1 | early growth response 1 | -0.0555371 |
| TPM4 | tropomyosin 4 | -0.0546331 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0510197 |
| OSMR | oncostatin M receptor | -0.049338 |
| SBF2 | SET binding factor 2 | -0.047571 |
| RPS6 | ribosomal protein S6 | -0.04734 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0467866 |
| KYNU | kynureninase | -0.0461575 |
| PHF14 | PHD finger protein 14 | -0.0456183 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0452739 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0441724 |
| ASPH | aspartate beta-hydroxylase | -0.0426247 |
| VCL | vinculin | -0.0425733 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | -0.0416327 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0410599 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0405907 |
| LOX | lysyl oxidase | -0.0405873 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0400355 |
| MT1X | metallothionein 1X | -0.0398608 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0394661 |
| B2M | beta-2-microglobulin | -0.0385197 |
| VMP1 | vacuole membrane protein 1 | -0.0384386 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0381944 |
| COPA | coatomer protein complex, subunit alpha | -0.0380624 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0372786 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0370721 |
| GOLGB1 | golgin B1 | -0.0366226 |
| ATM | ATM serine/threonine kinase | -0.035092 |
| RPL28 | ribosomal protein L28 | -0.0348156 |
| FBXO11 | F-box protein 11 | -0.034372 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0329959 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0315839 |
| RPL35A | ribosomal protein L35a | -0.0315815 |
| PRSS23 | protease, serine, 23 | -0.0314032 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0313826 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0311957 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0311278 |
| MORF4L2 | mortality factor 4 like 2 | -0.0310526 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0305695 |
| ZNF432 | zinc finger protein 432 | -0.0304199 |
| CLMP | CXADR-like membrane protein | -0.0303429 |
| NABP1 | nucleic acid binding protein 1 | -0.0303034 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0302198 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0301576 |
| SCFD2 | sec1 family domain containing 2 | -0.0293958 |
| GPATCH2L | G patch domain containing 2-like | -0.0293677 |
| RPLP2 | ribosomal protein, large, P2 | -0.0293448 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.0289901 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0281675 |
| ACTN1 | actinin, alpha 1 | -0.028148 |
| HM13 | histocompatibility (minor) 13 | -0.0280322 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.027897 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0276617 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.027551 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0274426 |
| IGF2 | insulin-like growth factor 2 | -0.0272924 |
| CALR | calreticulin | -0.0271434 |
| MYADM | myeloid-associated differentiation marker | -0.0270949 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0269771 |
| BPTF | bromodomain PHD finger transcription factor | -0.0267962 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0267936 |
| SON | SON DNA binding protein | -0.026604 |
| OXR1 | oxidation resistance 1 | -0.026528 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0264508 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.026392 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0260932 |
| RPLP1 | ribosomal protein, large, P1 | -0.0259493 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0259484 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0257391 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0257365 |
| RPL9 | ribosomal protein L9 | -0.0257348 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0255388 |
| STC1 | stanniocalcin 1 | -0.0254366 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0249914 |
| GOLGA4 | golgin A4 | -0.0248232 |
| MCL1 | myeloid cell leukemia 1 | -0.0248069 |
| RPS13 | ribosomal protein S13 | -0.0247731 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0244469 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.024399 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0243795 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0241832 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0241422 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0240088 |
| COG5 | component of oligomeric golgi complex 5 | -0.0239887 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0238443 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0235999 |
| RPL27A | ribosomal protein L27a | -0.0234719 |
| MYO9A | myosin IXA | -0.0234611 |