| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.229646 |
| COL6A3 | collagen, type VI, alpha 3 | 0.226082 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.147666 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.138784 |
| VEGFA | vascular endothelial growth factor A | 0.107204 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0909167 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0837463 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0748945 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0673894 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0658124 |
| CADM1 | cell adhesion molecule 1 | 0.0615195 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0613983 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0603646 |
| COL5A1 | collagen, type V, alpha 1 | 0.0587595 |
| EGFR | epidermal growth factor receptor | 0.0579927 |
| PDE10A | phosphodiesterase 10A | 0.0550605 |
| CALD1 | caldesmon 1 | 0.0532185 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0505904 |
| ARRDC3 | arrestin domain containing 3 | 0.0501175 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0488989 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0483083 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0478669 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0476164 |
| POTEF | POTE ankyrin domain family, member F | 0.0466823 |
| EFNA5 | ephrin-A5 | 0.0461006 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0453575 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0449778 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0445436 |
| MSN | moesin | 0.0436685 |
| ENO1 | enolase 1, (alpha) | 0.043317 |
| ATP13A3 | ATPase type 13A3 | 0.0431723 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0427285 |
| MYO10 | myosin X | 0.0418964 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0412872 |
| INHBA | inhibin, beta A | 0.0395871 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0391528 |
| AXL | AXL receptor tyrosine kinase | 0.0385158 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0382568 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0380435 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0370648 |
| NBAS | neuroblastoma amplified sequence | 0.0361567 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0358037 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0353941 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0348789 |
| SDC4 | syndecan 4 | 0.0341059 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0340658 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0336206 |
| DST | dystonin | 0.0335436 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0332979 |
| ACTG1 | actin gamma 1 | 0.0332769 |
| NOTCH2 | notch 2 | 0.0330138 |
| CCNL1 | cyclin L1 | 0.0326297 |
| CLIC4 | chloride intracellular channel 4 | 0.0324513 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0323216 |
| MTSS1 | metastasis suppressor 1 | 0.0321367 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0316819 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0315071 |
| GSK3B | glycogen synthase kinase 3 beta | 0.031268 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0306285 |
| TNS1 | tensin 1 | 0.0302056 |
| GOLGA4 | golgin A4 | 0.0298988 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.029874 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0296275 |
| APP | amyloid beta (A4) precursor protein | 0.0293525 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0293294 |
| NAV2 | neuron navigator 2 | 0.0292978 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0292731 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0292333 |
| SMAD3 | SMAD family member 3 | 0.0290616 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0289355 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0288988 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0284962 |
| COL4A1 | collagen, type IV, alpha 1 | 0.028383 |
| TMF1 | TATA element modulatory factor 1 | 0.0283344 |
| SDC2 | syndecan 2 | 0.0281201 |
| RNF220 | ring finger protein 220 | 0.0280989 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0280061 |
| PCBP2 | poly(rC) binding protein 2 | 0.0275399 |
| PTK2 | protein tyrosine kinase 2 | 0.0275045 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0274739 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0274495 |
| TPM3 | tropomyosin 3 | 0.0272441 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0271664 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0269365 |
| CMIP | c-Maf inducing protein | 0.0268935 |
| SETD5 | SET domain containing 5 | 0.026406 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0263353 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0263115 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0261158 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0261034 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.025613 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0252721 |
| STC2 | stanniocalcin 2 | 0.0252238 |
| CD109 | CD109 molecule | 0.0249168 |
| RUNX1 | runt-related transcription factor 1 | 0.0244979 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0243245 |
| SEPTIN9 | septin 9 | 0.0243151 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0242784 |
| B2M | beta-2-microglobulin | 0.023942 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0238868 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.299249 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232514 |
| VIM | vimentin | -0.231425 |
| NDRG1 | N-myc downstream regulated 1 | -0.168463 |
| TMSB10 | thymosin beta 10 | -0.144808 |
| FN1 | fibronectin 1 | -0.13652 |
| MT2A | metallothionein 2A | -0.0802284 |
| COL1A1 | collagen, type I, alpha 1 | -0.0775799 |
| FTL | ferritin, light polypeptide | -0.0644623 |
| HMGA2 | high mobility group AT-hook 2 | -0.0605718 |
| CD44 | CD44 molecule (Indian blood group) | -0.0603515 |
| RRBP1 | ribosome binding protein 1 | -0.0573716 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0524944 |
| OSMR | oncostatin M receptor | -0.0501992 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0463783 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.046357 |
| RPL35A | ribosomal protein L35a | -0.0454266 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0416092 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0414078 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0392458 |
| IER3 | immediate early response 3 | -0.0383076 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0379375 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0348685 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0323228 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0306167 |
| CAVIN1 | caveolae associated protein 1 | -0.0297677 |
| RACK1 | receptor for activated C kinase 1 | -0.0280674 |
| GNAS | GNAS complex locus | -0.0279983 |
| EGR1 | early growth response 1 | -0.0274781 |
| ANXA2 | annexin A2 | -0.0273766 |
| RPS24 | ribosomal protein S24 | -0.0273754 |
| LMNA | lamin A/C | -0.0272812 |
| TMEM263 | transmembrane protein 263 | -0.0272772 |
| RPS8 | ribosomal protein S8 | -0.0272444 |
| TUBB | tubulin, beta class I | -0.0267277 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0264666 |
| RPL32 | ribosomal protein L32 | -0.0260071 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0255467 |
| RPLP1 | ribosomal protein, large, P1 | -0.0252962 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0250886 |
| RPL11 | ribosomal protein L11 | -0.0250531 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0249308 |
| RPL34 | ribosomal protein L34 | -0.024593 |
| PTMA | prothymosin, alpha | -0.0244719 |
| RPL28 | ribosomal protein L28 | -0.0241528 |
| S100A10 | S100 calcium binding protein A10 | -0.0239832 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.023276 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0229802 |
| RPS5 | ribosomal protein S5 | -0.0229046 |
| H1-0 | H1.0 linker histone | -0.0226729 |
| KLF6 | Kruppel-like factor 6 | -0.0226535 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0225299 |
| RPL26 | ribosomal protein L26 | -0.0219204 |
| ARF1 | ADP-ribosylation factor 1 | -0.0219144 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0217302 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0215811 |
| RPL8 | ribosomal protein L8 | -0.0213758 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0211209 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.020916 |
| CENPF | centromere protein F, 350/400kDa | -0.0207032 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0204493 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0202229 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0202127 |
| RPS23 | ribosomal protein S23 | -0.0201807 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0199729 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0198321 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0198133 |
| S100A9 | S100 calcium binding protein A9 | -0.0197104 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0196719 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0195863 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0194803 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0193053 |
| RPS19 | ribosomal protein S19 | -0.0192983 |
| RPL12 | ribosomal protein L12 | -0.018627 |
| EHD2 | EH-domain containing 2 | -0.018487 |
| RPLP0 | ribosomal protein, large, P0 | -0.018162 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0180153 |
| TKT | transketolase | -0.0179442 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0178154 |
| CENPE | centromere protein E, 312kDa | -0.0178037 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0175301 |
| NREP | neuronal regeneration related protein | -0.0174098 |
| PLSCR1 | phospholipid scramblase 1 | -0.0172166 |
| RPS21 | ribosomal protein S21 | -0.0171425 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0170479 |
| SERINC1 | serine incorporator 1 | -0.0169083 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0168757 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0166559 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0162338 |
| PGK1 | phosphoglycerate kinase 1 | -0.0162058 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0160477 |
| RPL31 | ribosomal protein L31 | -0.0160125 |
| SP100 | SP100 nuclear antigen | -0.0158124 |
| LOXL2 | lysyl oxidase-like 2 | -0.0156013 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0155855 |
| TENM1 | teneurin transmembrane protein 1 | -0.0155056 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0154656 |
| RPL30 | ribosomal protein L30 | -0.0153457 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.0153208 |
| PXDN | peroxidasin | -0.0152518 |
