| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATAD2 | ATPase family, AAA domain containing 2 | 0.141858 |
| EXT1 | exostosin glycosyltransferase 1 | 0.113805 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0989739 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0844124 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0815329 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0813827 |
| GOLGA4 | golgin A4 | 0.0762473 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0748444 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0734295 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0732386 |
| PCBP2 | poly(rC) binding protein 2 | 0.0722735 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0677037 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0665609 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0639006 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0633522 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0621992 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.06206 |
| LDHA | lactate dehydrogenase A | 0.059379 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0589428 |
| CCNY | cyclin Y | 0.0582276 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0576169 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0567938 |
| PTK2 | protein tyrosine kinase 2 | 0.054099 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0537047 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0531894 |
| DIAPH3 | diaphanous-related formin 3 | 0.0527812 |
| NDRG1 | N-myc downstream regulated 1 | 0.0523856 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0505683 |
| NUP58 | nucleoporin 58 | 0.0504189 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0493949 |
| FAM13A | family with sequence similarity 13, member A | 0.0491447 |
| HYOU1 | hypoxia up-regulated 1 | 0.0485298 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0484907 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0480365 |
| B2M | beta-2-microglobulin | 0.0453918 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0449504 |
| SPAG9 | sperm associated antigen 9 | 0.044797 |
| RTN3 | reticulon 3 | 0.044127 |
| HELZ | helicase with zinc finger | 0.0437897 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0428691 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0417933 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0412356 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0411906 |
| SUCO | SUN domain containing ossification factor | 0.0400552 |
| BRD2 | bromodomain containing 2 | 0.0398505 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0390715 |
| DIAPH1 | diaphanous-related formin 1 | 0.0389176 |
| PDS5B | PDS5 cohesin associated factor B | 0.0387291 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0384687 |
| FBXO32 | F-box protein 32 | 0.0380474 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0378905 |
| CCNL1 | cyclin L1 | 0.0374799 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.037328 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0369847 |
| PTEN | phosphatase and tensin homolog | 0.0369082 |
| OGA | O-GlcNAcase | 0.0368098 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0366216 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0365612 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0359646 |
| TMEM65 | transmembrane protein 65 | 0.0359324 |
| RPL21 | ribosomal protein L21 | 0.0357752 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0353669 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0353367 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0344973 |
| NCKAP1 | NCK-associated protein 1 | 0.0344781 |
| USP3 | ubiquitin specific peptidase 3 | 0.0343891 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0343749 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0343641 |
| CDK8 | cyclin-dependent kinase 8 | 0.0340767 |
| YME1L1 | YME1-like 1 ATPase | 0.0339807 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0338446 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.033793 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0337591 |
| COPA | coatomer protein complex, subunit alpha | 0.0337518 |
| NBAS | neuroblastoma amplified sequence | 0.0335144 |
| VEGFA | vascular endothelial growth factor A | 0.0332756 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0329742 |
| KRT8 | keratin 8, type II | 0.0328677 |
| RBM33 | RNA binding motif protein 33 | 0.032846 |
| ZNF292 | zinc finger protein 292 | 0.0328303 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0324864 |
| XPO1 | exportin 1 | 0.0322754 |
| TPM3 | tropomyosin 3 | 0.0321996 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0318009 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0317745 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0317349 |
| RTN4 | reticulon 4 | 0.0316919 |
| RREB1 | ras responsive element binding protein 1 | 0.031605 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0315768 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0313811 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0313258 |
| PHF20L1 | PHD finger protein 20-like 1 | 0.0312836 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0312302 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.03109 |
| ZNF638 | zinc finger protein 638 | 0.030777 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0307751 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0307118 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0306683 |
| CALU | calumenin | 0.0306536 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0305923 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.146485 |
| LAMA4 | laminin, alpha 4 | -0.0912589 |
| PTMA | prothymosin, alpha | -0.0749913 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0748368 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0712289 |
| TMSB10 | thymosin beta 10 | -0.0638303 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0619154 |
| ACTN4 | actinin, alpha 4 | -0.0599486 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0580793 |
| EGR1 | early growth response 1 | -0.0577458 |
| RPS24 | ribosomal protein S24 | -0.0562895 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0556378 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0547442 |
| TRIB1 | tribbles pseudokinase 1 | -0.0536781 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0536612 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.050324 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0466932 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0444375 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0427618 |
| KRT20 | keratin 20, type I | -0.0422113 |
| H1-0 | H1.0 linker histone | -0.0414101 |
| CENPF | centromere protein F, 350/400kDa | -0.0413231 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.040415 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0386231 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0373796 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0372995 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0370945 |
| TMEM123 | transmembrane protein 123 | -0.0370903 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0359804 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0355829 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0354994 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0337897 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0333533 |
| POF1B | premature ovarian failure, 1B | -0.0330785 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0329322 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0323305 |
| SMAD3 | SMAD family member 3 | -0.0321228 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0319354 |
| EZR | ezrin | -0.0319292 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0317984 |
| MKI67 | marker of proliferation Ki-67 | -0.0313052 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0308038 |
| CENPE | centromere protein E, 312kDa | -0.0306502 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0303519 |
| KLF10 | Kruppel-like factor 10 | -0.0301267 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0300632 |
| ETV6 | ets variant 6 | -0.0297932 |
| STK24 | serine/threonine kinase 24 | -0.029528 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0290332 |
| RPS6 | ribosomal protein S6 | -0.0289461 |
| SULF2 | sulfatase 2 | -0.0289385 |
| AREG | amphiregulin | -0.0286412 |
| CD2AP | CD2-associated protein | -0.028441 |
| KLF6 | Kruppel-like factor 6 | -0.0281137 |
| PYGB | phosphorylase, glycogen; brain | -0.0280735 |
| LMO7 | LIM domain 7 | -0.0273516 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0269678 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0269427 |
| RPL35A | ribosomal protein L35a | -0.0265755 |
| ASPH | aspartate beta-hydroxylase | -0.0263146 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0260394 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0257969 |
| RPL12 | ribosomal protein L12 | -0.0256311 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0254234 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0251905 |
| RPL34 | ribosomal protein L34 | -0.0250496 |
| DIAPH2 | diaphanous-related formin 2 | -0.0249539 |
| HMGB1 | high mobility group box 1 | -0.0244224 |
| VIM | vimentin | -0.0243399 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0240956 |
| SEPTIN9 | septin 9 | -0.0231302 |
| BPTF | bromodomain PHD finger transcription factor | -0.0230986 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0230983 |
| S100A10 | S100 calcium binding protein A10 | -0.0230482 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.022991 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0228749 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0227876 |
| RPL6 | ribosomal protein L6 | -0.0226847 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0225178 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.022249 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0219271 |
| MIDN | midnolin | -0.0218975 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0217329 |
| GSN | gelsolin | -0.0212823 |
| ABLIM1 | actin binding LIM protein 1 | -0.0207617 |
| LMNA | lamin A/C | -0.0207276 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0204448 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0203727 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0202738 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0201296 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0199401 |
| IER3 | immediate early response 3 | -0.0196646 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0195423 |
| ITGA1 | integrin, alpha 1 | -0.0194149 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0192779 |
| RPS25 | ribosomal protein S25 | -0.0192226 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0190679 |
| FOXP1 | forkhead box P1 | -0.018853 |
| POMP | proteasome maturation protein | -0.0187522 |
| KLF13 | Kruppel-like factor 13 | -0.0187305 |