| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.155632 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.110666 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.108634 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0990866 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0965727 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0916735 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0882877 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0834643 |
| APOB | apolipoprotein B | 0.0832839 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0786074 |
| ENO1 | enolase 1, (alpha) | 0.0739499 |
| DSPP | dentin sialophosphoprotein | 0.0723125 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0656616 |
| SDC4 | syndecan 4 | 0.0612507 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0597852 |
| DTNA | dystrobrevin, alpha | 0.0567287 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0563133 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0543852 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0531638 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0524343 |
| FN1 | fibronectin 1 | 0.0520813 |
| PEG3 | paternally expressed 3 | 0.0520026 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0516906 |
| ATXN1 | ataxin 1 | 0.0502136 |
| AFDN | afadin, adherens junction formation factor | 0.0495039 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0493368 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0481666 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0481314 |
| KIAA1217 | KIAA1217 | 0.0472264 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0465393 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0461595 |
| FMNL2 | formin-like 2 | 0.0453264 |
| EHBP1 | EH domain binding protein 1 | 0.0441591 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0426143 |
| TNS1 | tensin 1 | 0.0420395 |
| FRMD5 | FERM domain containing 5 | 0.0417194 |
| RNF213 | ring finger protein 213 | 0.0404862 |
| INSIG2 | insulin induced gene 2 | 0.0387132 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0377363 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0374753 |
| ASPH | aspartate beta-hydroxylase | 0.0374533 |
| ZNF292 | zinc finger protein 292 | 0.0372252 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0368645 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0364974 |
| NDRG1 | N-myc downstream regulated 1 | 0.0363894 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0348306 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0347757 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0338647 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0331784 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0328225 |
| MSI2 | musashi RNA-binding protein 2 | 0.0326036 |
| PLXDC2 | plexin domain containing 2 | 0.032466 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0324423 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0322379 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0321465 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0311718 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0309575 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0308683 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0305067 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0300127 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0299971 |
| PRELID2 | PRELI domain containing 2 | 0.0296868 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0295608 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.029482 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0293224 |
| RBM39 | RNA binding motif protein 39 | 0.0292562 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0289413 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0289359 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0289229 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0288794 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0284206 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.028074 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0279657 |
| OSMR | oncostatin M receptor | 0.0279608 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0279248 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0278166 |
| CCNY | cyclin Y | 0.02767 |
| FRK | fyn-related Src family tyrosine kinase | 0.0275687 |
| ITGA1 | integrin, alpha 1 | 0.0274667 |
| DENND4A | DENN/MADD domain containing 4A | 0.0273553 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0269793 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0269581 |
| CRLS1 | cardiolipin synthase 1 | 0.0269566 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0268306 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0266626 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0266001 |
| ABAT | 4-aminobutyrate aminotransferase | 0.0265815 |
| RREB1 | ras responsive element binding protein 1 | 0.0265175 |
| DENND1A | DENN/MADD domain containing 1A | 0.026516 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0264718 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0262035 |
| JMJD1C | jumonji domain containing 1C | 0.0253135 |
| PDE8A | phosphodiesterase 8A | 0.0251511 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0250789 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0250358 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0250137 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0249194 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.02464 |
| CANX | calnexin | 0.0246292 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0245629 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.415429 |
| MT2A | metallothionein 2A | -0.159353 |
| IGF2 | insulin-like growth factor 2 | -0.113005 |
| SLC38A2 | solute carrier family 38, member 2 | -0.082992 |
| VCL | vinculin | -0.0804533 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0790398 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0712393 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0607575 |
| FTL | ferritin, light polypeptide | -0.0589375 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0588168 |
| APOA2 | apolipoprotein A-II | -0.0575296 |
| EGR1 | early growth response 1 | -0.05448 |
| RPS6 | ribosomal protein S6 | -0.0538556 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0535179 |
| RPS12 | ribosomal protein S12 | -0.0492124 |
| RPLP1 | ribosomal protein, large, P1 | -0.0452171 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0442768 |
| BCL2L1 | BCL2-like 1 | -0.0429884 |
| RPS19 | ribosomal protein S19 | -0.0410613 |
| ZNF644 | zinc finger protein 644 | -0.0386542 |
| RPL12 | ribosomal protein L12 | -0.0382114 |
| RPL37A | ribosomal protein L37a | -0.0365251 |
| ITGAV | integrin, alpha V | -0.0356351 |
| RPS23 | ribosomal protein S23 | -0.0348529 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0328253 |
| RPL11 | ribosomal protein L11 | -0.0317073 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0313716 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0309698 |
| RPS3 | ribosomal protein S3 | -0.0306704 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0304385 |
| RPL35A | ribosomal protein L35a | -0.0301844 |
| RPS8 | ribosomal protein S8 | -0.0299655 |
| APOE | apolipoprotein E | -0.0294948 |
| DSTN | destrin (actin depolymerizing factor) | -0.0294916 |
| RPS27A | ribosomal protein S27a | -0.0291604 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0282836 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0272783 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0271133 |
| RBM25 | RNA binding motif protein 25 | -0.0264902 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0258305 |
| RACK1 | receptor for activated C kinase 1 | -0.0257756 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0257291 |
| TPM1 | tropomyosin 1 (alpha) | -0.0256977 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0249183 |
| RPL36 | ribosomal protein L36 | -0.0243517 |
| RPL5 | ribosomal protein L5 | -0.0242763 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0238341 |
| STK17A | serine/threonine kinase 17a | -0.0237268 |
| RPL28 | ribosomal protein L28 | -0.0236863 |
| CCN2 | cellular communication network factor 2 | -0.02305 |
| RPS29 | ribosomal protein S29 | -0.0225235 |
| RPS14 | ribosomal protein S14 | -0.0222096 |
| RPL8 | ribosomal protein L8 | -0.0221249 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.02195 |
| YBX1 | Y box binding protein 1 | -0.0219389 |
| RPS13 | ribosomal protein S13 | -0.0216736 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0215075 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0214826 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0214503 |
| RPL34 | ribosomal protein L34 | -0.0210394 |
| HMGA1 | high mobility group AT-hook 1 | -0.0209916 |
| RPS24 | ribosomal protein S24 | -0.0209245 |
| VEGFA | vascular endothelial growth factor A | -0.0208547 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0206655 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0203623 |
| LATS2 | large tumor suppressor kinase 2 | -0.0201572 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0201227 |
| RPS27 | ribosomal protein S27 | -0.0199886 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0198723 |
| RPL31 | ribosomal protein L31 | -0.0196435 |
| TMSB10 | thymosin beta 10 | -0.019597 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.019567 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.019477 |
| CADM1 | cell adhesion molecule 1 | -0.0192815 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.019228 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0191438 |
| APOA1 | apolipoprotein A-I | -0.0189491 |
| RPLP2 | ribosomal protein, large, P2 | -0.0186087 |
| AHSG | alpha-2-HS-glycoprotein | -0.0184703 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.018277 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0182403 |
| SYNJ2 | synaptojanin 2 | -0.0182261 |
| PFN1 | profilin 1 | -0.0180975 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0180885 |
| TXNRD1 | thioredoxin reductase 1 | -0.0179782 |
| ACTN4 | actinin, alpha 4 | -0.017832 |
| RPL26 | ribosomal protein L26 | -0.0175564 |
| FOXP1 | forkhead box P1 | -0.0173023 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0172044 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0171986 |
| FAM107B | family with sequence similarity 107, member B | -0.0171933 |
| RPL32 | ribosomal protein L32 | -0.016938 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0167084 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0166085 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0165265 |
| THBS1 | thrombospondin 1 | -0.0162817 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0162458 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0161979 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.0158921 |
| RPS11 | ribosomal protein S11 | -0.0158815 |
