| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.228011 |
| DSPP | dentin sialophosphoprotein | 0.108711 |
| LMO7 | LIM domain 7 | 0.0986492 |
| KRT8 | keratin 8, type II | 0.0928994 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0819795 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0786219 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0757238 |
| KITLG | KIT ligand | 0.0744409 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0722031 |
| FAM13A | family with sequence similarity 13, member A | 0.0706553 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0696117 |
| ANKRD11 | ankyrin repeat domain 11 | 0.068364 |
| KIAA1217 | KIAA1217 | 0.0682165 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0672983 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0653463 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0653253 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0651223 |
| RPS12 | ribosomal protein S12 | 0.0640694 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0639533 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0608858 |
| GDF15 | growth differentiation factor 15 | 0.0602801 |
| AREG | amphiregulin | 0.0582805 |
| GOLGA4 | golgin A4 | 0.0576692 |
| MED13L | mediator complex subunit 13-like | 0.0565029 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0564191 |
| PCBP2 | poly(rC) binding protein 2 | 0.0564048 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0558158 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0558065 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0555713 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0554606 |
| RBM39 | RNA binding motif protein 39 | 0.0551812 |
| FAT1 | FAT atypical cadherin 1 | 0.0551066 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0548966 |
| SDC4 | syndecan 4 | 0.0535722 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.053394 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0523575 |
| CALR | calreticulin | 0.0510963 |
| B2M | beta-2-microglobulin | 0.0508942 |
| ACTG1 | actin gamma 1 | 0.0504454 |
| FDXR | ferredoxin reductase | 0.0503416 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0496857 |
| APP | amyloid beta (A4) precursor protein | 0.0491067 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0484297 |
| YBX3 | Y box binding protein 3 | 0.0471493 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0469839 |
| EREG | epiregulin | 0.04676 |
| ETNK1 | ethanolamine kinase 1 | 0.0457129 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0451692 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0449534 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0446136 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0441174 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0440203 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0435982 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0426514 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.042469 |
| SPAG9 | sperm associated antigen 9 | 0.0424385 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0424348 |
| OGA | O-GlcNAcase | 0.0414435 |
| WDR45B | WD repeat domain 45B | 0.0413549 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.040852 |
| LAMA4 | laminin, alpha 4 | 0.0408302 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.040753 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0406992 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0405338 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0396703 |
| TMSB4X | thymosin beta 4, X-linked | 0.0395495 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0394267 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0391324 |
| RPS3 | ribosomal protein S3 | 0.0390649 |
| TPM3 | tropomyosin 3 | 0.0386251 |
| CANX | calnexin | 0.0384504 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0383539 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.0382313 |
| RPL26 | ribosomal protein L26 | 0.0380267 |
| TRIM24 | tripartite motif containing 24 | 0.0374432 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0373024 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0368906 |
| RPS8 | ribosomal protein S8 | 0.0365894 |
| LAMB3 | laminin, beta 3 | 0.0364175 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0363984 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0363777 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0354951 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0349666 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0348793 |
| RPL7 | ribosomal protein L7 | 0.0347345 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0346697 |
| AHNAK | AHNAK nucleoprotein | 0.0344463 |
| WDR43 | WD repeat domain 43 | 0.0343082 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0340363 |
| SHROOM3 | shroom family member 3 | 0.0340271 |
| LRRC1 | leucine rich repeat containing 1 | 0.0339668 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0338283 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0336171 |
| ZNF654 | zinc finger protein 654 | 0.0335987 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0332994 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0330657 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | 0.0330069 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0329838 |
| PARD3 | par-3 family cell polarity regulator | 0.0324829 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0324753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166557 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.134795 |
| NPSR1 | neuropeptide S receptor 1 | -0.119911 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.109021 |
| TNS4 | tensin 4 | -0.0923812 |
| TXNIP | thioredoxin interacting protein | -0.0825523 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0822419 |
| TMSB10 | thymosin beta 10 | -0.0786503 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0737018 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0736076 |
| CADPS | Ca++-dependent secretion activator | -0.0554251 |
| NDRG1 | N-myc downstream regulated 1 | -0.0531602 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0506742 |
| RNF43 | ring finger protein 43 | -0.0504932 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0446911 |
| EZR | ezrin | -0.0417791 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0375572 |
| FTL | ferritin, light polypeptide | -0.0369706 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0369142 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0368469 |
| FHIT | fragile histidine triad | -0.0366276 |
| H1-0 | H1.0 linker histone | -0.036552 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0361203 |
| CALB1 | calbindin 1, 28kDa | -0.0351207 |
| HMGA1 | high mobility group AT-hook 1 | -0.0344746 |
| MUC17 | mucin 17, cell surface associated | -0.0333852 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0332753 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0315957 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0300525 |
| CENPF | centromere protein F, 350/400kDa | -0.0289259 |
| PKP2 | plakophilin 2 | -0.0288616 |
| PRSS3 | protease, serine, 3 | -0.0281115 |
| DIAPH2 | diaphanous-related formin 2 | -0.0280994 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0278349 |
| TRIM2 | tripartite motif containing 2 | -0.0278188 |
| EGR1 | early growth response 1 | -0.0277879 |
| CCND1 | cyclin D1 | -0.0271404 |
| CDK6 | cyclin-dependent kinase 6 | -0.0262619 |
| ANXA2 | annexin A2 | -0.0259922 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0240796 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0236566 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0235519 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0223978 |
| RNF217 | ring finger protein 217 | -0.0220565 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.021987 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0218106 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0217769 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0212903 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0209 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0207591 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0201614 |
| FLNB | filamin B, beta | -0.0198583 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0196968 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0192718 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0192233 |
| FOSL1 | FOS-like antigen 1 | -0.0190759 |
| FOXP1 | forkhead box P1 | -0.0188776 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0187553 |
| CBX3 | chromobox homolog 3 | -0.0186857 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0185233 |
| PKM | pyruvate kinase, muscle | -0.0182483 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0180701 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.017941 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0178225 |
| PHGR1 | proline/histidine/glycine-rich 1 | -0.0177974 |
| PRELID2 | PRELI domain containing 2 | -0.0177083 |
| PFN1 | profilin 1 | -0.0176232 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0172124 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0169345 |
| LSAMP | limbic system-associated membrane protein | -0.0168954 |
| NFIA | nuclear factor I/A | -0.0167534 |
| TMEM123 | transmembrane protein 123 | -0.0166879 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.016565 |
| ABR | active BCR-related | -0.0165592 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0164505 |
| TC2N | tandem C2 domains, nuclear | -0.0163156 |
| S100A10 | S100 calcium binding protein A10 | -0.0162466 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0159477 |
| ATXN1 | ataxin 1 | -0.0158671 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0157503 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0156933 |
| CLDN7 | claudin 7 | -0.0155149 |
| KRT19 | keratin 19, type I | -0.0154361 |
| CENPE | centromere protein E, 312kDa | -0.0153535 |
| EPHB2 | EPH receptor B2 | -0.0153516 |
| MT1X | metallothionein 1X | -0.0153412 |
| MECOM | MDS1 and EVI1 complex locus | -0.0152815 |
| TRABD2A | TraB domain containing 2A | -0.0151453 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0150553 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0148804 |
| PERP | PERP, TP53 apoptosis effector | -0.0148273 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0147274 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0146655 |
| RPL31 | ribosomal protein L31 | -0.0145846 |
| PTCH1 | patched 1 | -0.014511 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0145004 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0144382 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0143512 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0141578 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0141197 |
