| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0753125 |
| FAM13A | family with sequence similarity 13, member A | 0.0715254 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.071108 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0667088 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0657127 |
| ARRDC3 | arrestin domain containing 3 | 0.0652842 |
| SLTM | SAFB-like, transcription modulator | 0.0645894 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0643357 |
| RUNX1 | runt-related transcription factor 1 | 0.0635727 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0596086 |
| ANKRD10 | ankyrin repeat domain 10 | 0.059321 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0581093 |
| CES1 | carboxylesterase 1 | 0.056285 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0545362 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0541497 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0540835 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0523121 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0518396 |
| DENND4A | DENN/MADD domain containing 4A | 0.0485181 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.048219 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0477359 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.047263 |
| SMAD3 | SMAD family member 3 | 0.0462298 |
| PGK1 | phosphoglycerate kinase 1 | 0.0455821 |
| NGLY1 | N-glycanase 1 | 0.0452539 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0443801 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0436145 |
| FNIP1 | folliculin interacting protein 1 | 0.0417927 |
| KIAA1217 | KIAA1217 | 0.0416793 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.041621 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0415028 |
| ATP13A3 | ATPase type 13A3 | 0.0414838 |
| ENO1 | enolase 1, (alpha) | 0.0413108 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0405285 |
| ZNF292 | zinc finger protein 292 | 0.0396093 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0391698 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0383541 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0379129 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0379109 |
| HELZ | helicase with zinc finger | 0.0376906 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0372391 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0367178 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0364986 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0360167 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0358444 |
| YEATS2 | YEATS domain containing 2 | 0.0356836 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0355672 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0354468 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.035436 |
| RPL4 | ribosomal protein L4 | 0.0353534 |
| DTNA | dystrobrevin, alpha | 0.0351704 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0348866 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0346008 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.034414 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0339957 |
| PCBP2 | poly(rC) binding protein 2 | 0.0339231 |
| PLEC | plectin | 0.033834 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0332574 |
| OGA | O-GlcNAcase | 0.0329685 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0326168 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0325091 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0322963 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0320183 |
| SUCO | SUN domain containing ossification factor | 0.0315037 |
| RAD51B | RAD51 paralog B | 0.0314066 |
| NPTN | neuroplastin | 0.0310381 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0310183 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0308264 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.030716 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0299776 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0299491 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0298666 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0298493 |
| GPHN | gephyrin | 0.0297152 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0294354 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0294231 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0293936 |
| EP300 | E1A binding protein p300 | 0.0292659 |
| CLTC | clathrin, heavy chain (Hc) | 0.029068 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0289868 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0288222 |
| RYBP | RING1 and YY1 binding protein | 0.028703 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0284836 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0283019 |
| TMEM165 | transmembrane protein 165 | 0.0279627 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0279116 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0273202 |
| GPATCH2L | G patch domain containing 2-like | 0.027172 |
| GPC6 | glypican 6 | 0.0271317 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0270145 |
| HYOU1 | hypoxia up-regulated 1 | 0.0270126 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0268323 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.02666 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.026612 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0265485 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0264911 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0263217 |
| YTHDC1 | YTH domain containing 1 | 0.0261565 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0260693 |
| NBAS | neuroblastoma amplified sequence | 0.0259057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.119231 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115216 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.111767 |
| MT2A | metallothionein 2A | -0.111752 |
| LMO7 | LIM domain 7 | -0.0922867 |
| LAMA4 | laminin, alpha 4 | -0.0816741 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0736938 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0713444 |
| MKI67 | marker of proliferation Ki-67 | -0.0692818 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0674142 |
| FTL | ferritin, light polypeptide | -0.0613507 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0590601 |
| PTMA | prothymosin, alpha | -0.0551156 |
| ANXA2 | annexin A2 | -0.0535421 |
| H1-0 | H1.0 linker histone | -0.052353 |
| LAMC2 | laminin, gamma 2 | -0.049171 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0488218 |
| TMSB10 | thymosin beta 10 | -0.04685 |
| OSMR | oncostatin M receptor | -0.0468302 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0467033 |
| MT1X | metallothionein 1X | -0.0452454 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0433096 |
| SCEL | sciellin | -0.0400596 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0381061 |
| EGR1 | early growth response 1 | -0.0363636 |
| DSPP | dentin sialophosphoprotein | -0.0356267 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0356246 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0355387 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0353366 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0345876 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0343747 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0341104 |
| EGFR | epidermal growth factor receptor | -0.0336963 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0333821 |
| GRAMD1B | GRAM domain containing 1B | -0.0330312 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0326457 |
| EMP1 | epithelial membrane protein 1 | -0.0318131 |
| S100P | S100 calcium binding protein P | -0.0305266 |
| GM2A | GM2 ganglioside activator | -0.0297701 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0295912 |
| S100A11 | S100 calcium binding protein A11 | -0.0288277 |
| FOXP1 | forkhead box P1 | -0.028403 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0279813 |
| ANXA1 | annexin A1 | -0.0279585 |
| CUX1 | cut-like homeobox 1 | -0.0274307 |
| RIN2 | Ras and Rab interactor 2 | -0.0267685 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0266208 |
| AHNAK | AHNAK nucleoprotein | -0.0264533 |
| CSTB | cystatin B (stefin B) | -0.0264017 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0263434 |
| LIPH | lipase, member H | -0.0262747 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0261766 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.026082 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0260303 |
| MGAT4C | MGAT4 family, member C | -0.0260274 |
| EHBP1 | EH domain binding protein 1 | -0.0257931 |
| MRTFB | myocardin related transcription factor B | -0.0257673 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0257645 |
| S100A6 | S100 calcium binding protein A6 | -0.0257248 |
| NDRG1 | N-myc downstream regulated 1 | -0.0256402 |
| S100A10 | S100 calcium binding protein A10 | -0.0254415 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0241401 |
| RAB10 | RAB10, member RAS oncogene family | -0.0239741 |
| PERP | PERP, TP53 apoptosis effector | -0.023837 |
| SYAP1 | synapse associated protein 1 | -0.0238293 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0237901 |
| NTN4 | netrin 4 | -0.0225957 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0224585 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0221211 |
| RPL35A | ribosomal protein L35a | -0.0217987 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0212187 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0211818 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0206347 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0202785 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0200805 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.019854 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0197546 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0195835 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0195821 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0195729 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0194202 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0193769 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0193382 |
| SMIM14 | small integral membrane protein 14 | -0.0193326 |
| ETV6 | ets variant 6 | -0.0190766 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0190217 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0189224 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0188445 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0186894 |
| NEBL | nebulette | -0.0186035 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0185512 |
| ACTG1 | actin gamma 1 | -0.0184429 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0183638 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.018281 |
| ATP11A | ATPase, class VI, type 11A | -0.0182515 |
| PCED1B | PC-esterase domain containing 1B | -0.018231 |
| PARD3 | par-3 family cell polarity regulator | -0.0179216 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.017795 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0176484 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0175312 |