Cytarabine (hydrochloride)_NCI-H1792 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Cytarabine (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Cytarabine (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PCBP2 poly(rC) binding protein 2 0.221478
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.11095
CXCL8 chemokine (C-X-C motif) ligand 8 0.0999244
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0975886
FAM13A family with sequence similarity 13, member A 0.0848157
GOLGA4 golgin A4 0.0765493
P4HB prolyl 4-hydroxylase, beta polypeptide 0.071244
MEF2A myocyte enhancer factor 2A 0.0658773
ATP13A3 ATPase type 13A3 0.0606473
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.060445
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.060312
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0536497
GRB10 growth factor receptor-bound protein 10 0.0526438
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.050851
KDM2A lysine (K)-specific demethylase 2A 0.0489917
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0489833
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0486609
ANKRD11 ankyrin repeat domain 11 0.0482555
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0477766
USP3 ubiquitin specific peptidase 3 0.0472982
SPAG9 sperm associated antigen 9 0.0466871
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0461321
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0453669
SDC4 syndecan 4 0.0447549
CNOT2 CCR4-NOT transcription complex, subunit 2 0.0447203
ENO1 enolase 1, (alpha) 0.0436361
UBA6 ubiquitin-like modifier activating enzyme 6 0.0423151
FN1 fibronectin 1 0.042058
POTEF POTE ankyrin domain family, member F 0.041935
OGA O-GlcNAcase 0.0410604
TRIO trio Rho guanine nucleotide exchange factor 0.0407575
BZW1 basic leucine zipper and W2 domains 1 0.0407192
MAP2K1 mitogen-activated protein kinase kinase 1 0.040447
RBM39 RNA binding motif protein 39 0.0401161
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.0401061
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0398086
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0396806
SEC23A Sec23 homolog A (S. cerevisiae) 0.0393813
PICALM phosphatidylinositol binding clathrin assembly protein 0.0390025
PTMA prothymosin, alpha 0.0384614
CD109 CD109 molecule 0.0379691
FAM20C family with sequence similarity 20, member C 0.0376268
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0376157
DENND4A DENN/MADD domain containing 4A 0.0374393
SIK3 SIK family kinase 3 0.0366752
LIMCH1 LIM and calponin homology domains 1 0.0365857
ITCH itchy E3 ubiquitin protein ligase 0.0365425
ACTG1 actin gamma 1 0.0363955
NGLY1 N-glycanase 1 0.0356813
KDM3A lysine (K)-specific demethylase 3A 0.0355591
APP amyloid beta (A4) precursor protein 0.0355026
RICTOR RPTOR independent companion of MTOR, complex 2 0.0354769
COPA coatomer protein complex, subunit alpha 0.0354166
RPL4 ribosomal protein L4 0.0352398
HELZ helicase with zinc finger 0.0348953
TMSB4X thymosin beta 4, X-linked 0.0341103
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0339754
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.033527
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0335112
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0333629
CSDE1 cold shock domain containing E1, RNA-binding 0.0333057
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0327199
COL7A1 collagen, type VII, alpha 1 0.0326817
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0326659
PID1 phosphotyrosine interaction domain containing 1 0.0326581
YME1L1 YME1-like 1 ATPase 0.0323399
S100A6 S100 calcium binding protein A6 0.032161
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0321461
AHNAK AHNAK nucleoprotein 0.0319427
ZFAND3 zinc finger, AN1-type domain 3 0.0316731
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0316205
WDR45B WD repeat domain 45B 0.0314055
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0312547
COL12A1 collagen, type XII, alpha 1 0.03123
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0310888
KPNB1 karyopherin (importin) beta 1 0.0310422
SDK1 sidekick cell adhesion molecule 1 0.0305328
CALR calreticulin 0.0304993
RUNX2 runt-related transcription factor 2 0.0303423
TPR translocated promoter region, nuclear basket protein 0.0303278
SRP54 signal recognition particle 54kDa 0.0302405
RAB8B RAB8B, member RAS oncogene family 0.0300343
DNER delta/notch-like EGF repeat containing 0.029995
BHLHE40 basic helix-loop-helix family, member e40 0.0298043
NBAS neuroblastoma amplified sequence 0.0297461
MARCHF6 membrane associated ring-CH-type finger 6 0.0294562
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0288515
PDIA4 protein disulfide isomerase family A, member 4 0.0286323
LDHA lactate dehydrogenase A 0.0284143
RAB1A RAB1A, member RAS oncogene family 0.0283844
RIOK3 RIO kinase 3 0.0282278
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0281098
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.0280007
EIF3B eukaryotic translation initiation factor 3, subunit B 0.0278471
DSCAM Down syndrome cell adhesion molecule 0.0276642
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0273461
MYOF myoferlin 0.0272638
EIF4B eukaryotic translation initiation factor 4B 0.0272125
MRPS6 mitochondrial ribosomal protein S6 0.0271616
IGFBP3 insulin-like growth factor binding protein 3 0.0271307

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.233867
NDRG1 N-myc downstream regulated 1 -0.109214
VIM vimentin -0.103918
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0953016
CD44 CD44 molecule (Indian blood group) -0.0901869
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0780693
FTL ferritin, light polypeptide -0.0746936
MT2A metallothionein 2A -0.0745651
TMSB10 thymosin beta 10 -0.0677134
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0662172
ELL2 elongation factor, RNA polymerase II, 2 -0.0582089
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0527645
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0474558
CDCP1 CUB domain containing protein 1 -0.0471291
OSMR oncostatin M receptor -0.0469806
GLCCI1 glucocorticoid induced 1 -0.0439727
ARHGAP5 Rho GTPase activating protein 5 -0.0435362
AKAP12 A kinase (PRKA) anchor protein 12 -0.0413566
NRP1 neuropilin 1 -0.0411526
RPS2 ribosomal protein S2 -0.0381466
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0380169
GPC6 glypican 6 -0.0371065
TGM2 transglutaminase 2 -0.0350021
HMGA2 high mobility group AT-hook 2 -0.0345217
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.0342461
H1-0 H1.0 linker histone -0.0338074
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0336474
TM4SF1 transmembrane 4 L six family member 1 -0.033612
PDE4D phosphodiesterase 4D, cAMP-specific -0.0332949
ATXN1 ataxin 1 -0.0322134
NTN4 netrin 4 -0.0315788
NAMPT nicotinamide phosphoribosyltransferase -0.0313883
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0299839
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0295795
EDIL3 EGF-like repeats and discoidin I-like domains 3 -0.0290851
HMGA1 high mobility group AT-hook 1 -0.0289454
STC1 stanniocalcin 1 -0.0286395
EFNA5 ephrin-A5 -0.0277551
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0276661
DUSP5 dual specificity phosphatase 5 -0.0273537
EGR1 early growth response 1 -0.0270302
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.0267428
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0262035
RPL32 ribosomal protein L32 -0.0261703
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0257701
RPS24 ribosomal protein S24 -0.0256375
KIAA1328 KIAA1328 -0.02563
TFPI2 tissue factor pathway inhibitor 2 -0.0250862
ANTXR2 anthrax toxin receptor 2 -0.0248861
RPL31 ribosomal protein L31 -0.0246548
USP34 ubiquitin specific peptidase 34 -0.0239182
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0232175
RNF24 ring finger protein 24 -0.0228686
TXNIP thioredoxin interacting protein -0.022588
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0223942
SLC38A2 solute carrier family 38, member 2 -0.0222598
PKM pyruvate kinase, muscle -0.0221596
S100A10 S100 calcium binding protein A10 -0.021665
ZNF385D zinc finger protein 385D -0.0211986
MTSS1 metastasis suppressor 1 -0.0210326
NAV2 neuron navigator 2 -0.0210194
WDPCP WD repeat containing planar cell polarity effector -0.0209808
NPC1 Niemann-Pick disease, type C1 -0.0206634
FER fer (fps/fes related) tyrosine kinase -0.0203523
UGP2 UDP-glucose pyrophosphorylase 2 -0.0202016
NRG1 neuregulin 1 -0.020103
ECE1 endothelin converting enzyme 1 -0.0199226
ANGPTL4 angiopoietin-like 4 -0.0196225
NIPBL Nipped-B homolog (Drosophila) -0.0194728
COPZ1 coatomer protein complex, subunit zeta 1 -0.0193125
SYT1 synaptotagmin I -0.0191202
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0189024
BMAL2 basic helix-loop-helix ARNT like 2 -0.0188635
GPAT3 glycerol-3-phosphate acyltransferase 3 -0.0188594
BTG1 B-cell translocation gene 1, anti-proliferative -0.0186116
CENPF centromere protein F, 350/400kDa -0.0185465
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0185036
PTPRM protein tyrosine phosphatase, receptor type, M -0.0179923
FOXP1 forkhead box P1 -0.0179673
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0179478
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0177199
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0176911
ANKRD28 ankyrin repeat domain 28 -0.0175212
TBC1D5 TBC1 domain family, member 5 -0.0174434
MKI67 marker of proliferation Ki-67 -0.0174374
RPS23 ribosomal protein S23 -0.0173516
BRD2 bromodomain containing 2 -0.0169626
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0169553
FNDC3B fibronectin type III domain containing 3B -0.0169408
MAST4 microtubule associated serine/threonine kinase family member 4 -0.0168956
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.016804
RPLP1 ribosomal protein, large, P1 -0.0168031
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -0.0167499
TPT1 tumor protein, translationally-controlled 1 -0.0167376
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0166504
TTC28 tetratricopeptide repeat domain 28 -0.0166095
EXT1 exostosin glycosyltransferase 1 -0.0165152
INTS6 integrator complex subunit 6 -0.0164502
ADNP activity-dependent neuroprotector homeobox -0.0162137
RPL28 ribosomal protein L28 -0.0161275