| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.195396 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.124966 |
| FGB | fibrinogen beta chain | 0.0958591 |
| POTEF | POTE ankyrin domain family, member F | 0.0869603 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0824418 |
| WWOX | WW domain containing oxidoreductase | 0.0727308 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0723945 |
| RRM2 | ribonucleotide reductase M2 | 0.0713495 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0668435 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.065764 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0597217 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0573548 |
| WDR43 | WD repeat domain 43 | 0.0571397 |
| TPM3 | tropomyosin 3 | 0.0516655 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0511617 |
| CCNL1 | cyclin L1 | 0.0511304 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0496712 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0495785 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0480541 |
| YBX3 | Y box binding protein 3 | 0.0472297 |
| PFN1 | profilin 1 | 0.0462216 |
| FGG | fibrinogen gamma chain | 0.0461383 |
| PCBP2 | poly(rC) binding protein 2 | 0.045526 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0446218 |
| USP3 | ubiquitin specific peptidase 3 | 0.041932 |
| TXNRD1 | thioredoxin reductase 1 | 0.040243 |
| RPL23 | ribosomal protein L23 | 0.0399959 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0395729 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0389329 |
| RAD51B | RAD51 paralog B | 0.0368064 |
| RPS21 | ribosomal protein S21 | 0.0362094 |
| DIAPH3 | diaphanous-related formin 3 | 0.0360129 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0344863 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0343966 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0340815 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0337352 |
| FAM168A | family with sequence similarity 168, member A | 0.0334713 |
| ECT2 | epithelial cell transforming 2 | 0.033274 |
| RPS12 | ribosomal protein S12 | 0.0332657 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0326646 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0326205 |
| TPI1 | triosephosphate isomerase 1 | 0.0320894 |
| NUP58 | nucleoporin 58 | 0.0314857 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0314677 |
| AHR | aryl hydrocarbon receptor | 0.0312228 |
| NNMT | nicotinamide N-methyltransferase | 0.030542 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0302565 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0301599 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0300123 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0292917 |
| RPL4 | ribosomal protein L4 | 0.0292721 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0291791 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0290416 |
| TFG | TRK-fused gene | 0.02847 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0277847 |
| OLA1 | Obg-like ATPase 1 | 0.0274753 |
| RTN4 | reticulon 4 | 0.027029 |
| TUBB | tubulin, beta class I | 0.0267221 |
| PRR16 | proline rich 16 | 0.0265942 |
| MORF4L1 | mortality factor 4 like 1 | 0.0265806 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0263255 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0256715 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0253353 |
| TUBA1B | tubulin, alpha 1b | 0.0251723 |
| NEGR1 | neuronal growth regulator 1 | 0.0251354 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.025016 |
| DEK | DEK proto-oncogene | 0.024966 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0245117 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0242459 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0238916 |
| RPL7 | ribosomal protein L7 | 0.0237911 |
| CBX5 | chromobox homolog 5 | 0.0237277 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0236472 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0235946 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.023439 |
| SDC4 | syndecan 4 | 0.0233185 |
| CHN1 | chimerin 1 | 0.0232548 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0232005 |
| FANCA | Fanconi anemia, complementation group A | 0.0231068 |
| JAK1 | Janus kinase 1 | 0.022945 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0227933 |
| ASPH | aspartate beta-hydroxylase | 0.0225609 |
| WTAP | Wilms tumor 1 associated protein | 0.0225505 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0225335 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0222718 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0222618 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0222215 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0221719 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0218916 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0218835 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0218326 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0218088 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0217057 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0215332 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0215145 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0214475 |
| ACTG1 | actin gamma 1 | 0.0214189 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0213356 |
| PNN | pinin, desmosome associated protein | 0.0213276 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0213094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.363626 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.155115 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.153034 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0950326 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0946396 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0928786 |
| PYGL | phosphorylase, glycogen, liver | -0.0894033 |
| FLNB | filamin B, beta | -0.087863 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0853415 |
| EGFR | epidermal growth factor receptor | -0.0795742 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0764855 |
| VIM | vimentin | -0.0748155 |
| CMIP | c-Maf inducing protein | -0.0743238 |
| FMNL2 | formin-like 2 | -0.0735532 |
| CAVIN1 | caveolae associated protein 1 | -0.065149 |
| IER3 | immediate early response 3 | -0.0567383 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0558216 |
| ERBIN | erbb2 interacting protein | -0.0536331 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0474244 |
| ZFHX3 | zinc finger homeobox 3 | -0.0458504 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0457831 |
| SNX14 | sorting nexin 14 | -0.0439115 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0431765 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0427659 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0424022 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0420357 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0395629 |
| CUX1 | cut-like homeobox 1 | -0.0395525 |
| MYOF | myoferlin | -0.0393594 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0393281 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0392576 |
| OSMR | oncostatin M receptor | -0.0382024 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.037539 |
| GRAMD1B | GRAM domain containing 1B | -0.0369485 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0367417 |
| NEBL | nebulette | -0.0363525 |
| CDK13 | cyclin-dependent kinase 13 | -0.0362432 |
| USP34 | ubiquitin specific peptidase 34 | -0.0361067 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0359305 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0355027 |
| NUMB | numb homolog (Drosophila) | -0.0352401 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0350225 |
| NDRG1 | N-myc downstream regulated 1 | -0.0343428 |
| SVIL | supervillin | -0.0337291 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0335366 |
| HLA-A | major histocompatibility complex, class I, A | -0.0331213 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0328814 |
| FAM107B | family with sequence similarity 107, member B | -0.0324326 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0322305 |
| CFDP1 | craniofacial development protein 1 | -0.0320292 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0320082 |
| HLA-E | major histocompatibility complex, class I, E | -0.0318039 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0307318 |
| SQSTM1 | sequestosome 1 | -0.0305409 |
| NF1 | neurofibromin 1 | -0.0304949 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0300523 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0298968 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.029679 |
| HM13 | histocompatibility (minor) 13 | -0.0293591 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0292551 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0291345 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0290443 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0284734 |
| ACTN1 | actinin, alpha 1 | -0.0284067 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0283265 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0281846 |
| FOXP1 | forkhead box P1 | -0.0276827 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0275717 |
| CEP350 | centrosomal protein 350kDa | -0.0275251 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0274714 |
| NEMF | nuclear export mediator factor | -0.0274501 |
| TPM4 | tropomyosin 4 | -0.0273436 |
| APP | amyloid beta (A4) precursor protein | -0.0272913 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0271001 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0270754 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0270239 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0270157 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0269954 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0269895 |
| RBM39 | RNA binding motif protein 39 | -0.0269125 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0268979 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0267227 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0266094 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0257721 |
| STC2 | stanniocalcin 2 | -0.0257613 |
| RUNX1 | runt-related transcription factor 1 | -0.0256824 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0252611 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0251734 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0250562 |
| RBM25 | RNA binding motif protein 25 | -0.0249068 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0248922 |
| CTBP2 | C-terminal binding protein 2 | -0.0248585 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0248216 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0247251 |
| RSPRY1 | ring finger and SPRY domain containing 1 | -0.0247039 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0245614 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.02455 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.024486 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.0243972 |
| USP36 | ubiquitin specific peptidase 36 | -0.0243151 |
