| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.170515 |
| SDC4 | syndecan 4 | 0.125086 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0973665 |
| PTK2 | protein tyrosine kinase 2 | 0.0942136 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0818757 |
| KRT17 | keratin 17, type I | 0.0718452 |
| RPS16 | ribosomal protein S16 | 0.0708137 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0695764 |
| RPS12 | ribosomal protein S12 | 0.0683747 |
| RPL23 | ribosomal protein L23 | 0.0670985 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.065847 |
| RPL34 | ribosomal protein L34 | 0.0657164 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0652582 |
| FN1 | fibronectin 1 | 0.0626007 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0617117 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0615418 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0600375 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.058775 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.058108 |
| RPS3 | ribosomal protein S3 | 0.0561516 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.053336 |
| RPS8 | ribosomal protein S8 | 0.0522398 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0518923 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0511891 |
| RPS19 | ribosomal protein S19 | 0.0509654 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0504203 |
| SLTM | SAFB-like, transcription modulator | 0.0502548 |
| FLNB | filamin B, beta | 0.0502013 |
| CCNH | cyclin H | 0.0497679 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0493423 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0492601 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0487912 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.048467 |
| NCKAP1 | NCK-associated protein 1 | 0.0472788 |
| SET | SET nuclear proto-oncogene | 0.0470085 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0467451 |
| RPS6 | ribosomal protein S6 | 0.0467135 |
| DSPP | dentin sialophosphoprotein | 0.0456908 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0456561 |
| NKTR | natural killer cell triggering receptor | 0.0453593 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0451533 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0446101 |
| NDRG1 | N-myc downstream regulated 1 | 0.0445877 |
| ANXA1 | annexin A1 | 0.0443906 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.044327 |
| PDE10A | phosphodiesterase 10A | 0.0441615 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0440959 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0440687 |
| LDHA | lactate dehydrogenase A | 0.0437425 |
| RACK1 | receptor for activated C kinase 1 | 0.043716 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0431476 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0431184 |
| PCBP2 | poly(rC) binding protein 2 | 0.0431021 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0429556 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0424955 |
| CD46 | CD46 molecule, complement regulatory protein | 0.042405 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.041757 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0415807 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0413435 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0405092 |
| PUM2 | pumilio RNA-binding family member 2 | 0.040429 |
| B2M | beta-2-microglobulin | 0.0402373 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0397891 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0394466 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.038941 |
| CREB5 | cAMP responsive element binding protein 5 | 0.038939 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0379572 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0377275 |
| SETD5 | SET domain containing 5 | 0.0376945 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0374846 |
| RPLP1 | ribosomal protein, large, P1 | 0.0374637 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0373482 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0368122 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.036421 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0364107 |
| CCNL1 | cyclin L1 | 0.0363116 |
| CALR | calreticulin | 0.0362266 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.035527 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.0353712 |
| TPM3 | tropomyosin 3 | 0.0351363 |
| USP32 | ubiquitin specific peptidase 32 | 0.0350758 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.034822 |
| RPL37 | ribosomal protein L37 | 0.0348205 |
| SEC24A | SEC24 family member A | 0.0347936 |
| WDR45B | WD repeat domain 45B | 0.0341467 |
| RYBP | RING1 and YY1 binding protein | 0.0338599 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0337415 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0335965 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0333475 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0332228 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0331933 |
| ATP13A3 | ATPase type 13A3 | 0.0330771 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0325236 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0324067 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0322827 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0321081 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0317458 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0317235 |
| PTGES2 | prostaglandin E synthase 2 | 0.0317111 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0316489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.175944 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.136897 |
| TXNRD1 | thioredoxin reductase 1 | -0.128282 |
| PARD3 | par-3 family cell polarity regulator | -0.124037 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.121292 |
| ATOSA | atos homolog A | -0.114528 |
| TJP1 | tight junction protein 1 | -0.105625 |
| ANXA2 | annexin A2 | -0.0921219 |
| VIM | vimentin | -0.0907673 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0888239 |
| STC1 | stanniocalcin 1 | -0.0888201 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.086873 |
| SVIL | supervillin | -0.0751622 |
| LAMC2 | laminin, gamma 2 | -0.0710247 |
| LAMB3 | laminin, beta 3 | -0.0708155 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0697943 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0694086 |
| AHNAK | AHNAK nucleoprotein | -0.0686747 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0665568 |
| MUC16 | mucin 16, cell surface associated | -0.0665184 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0661034 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0657452 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0656871 |
| JMJD1C | jumonji domain containing 1C | -0.06531 |
| USP3 | ubiquitin specific peptidase 3 | -0.0621253 |
| LSAMP | limbic system-associated membrane protein | -0.0616142 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0610688 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0603575 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0591097 |
| INHBA | inhibin, beta A | -0.0590639 |
| RBM47 | RNA binding motif protein 47 | -0.0590094 |
| EGR1 | early growth response 1 | -0.0588243 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0585957 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0581527 |
| ASPH | aspartate beta-hydroxylase | -0.0569746 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0562736 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0555523 |
| SQSTM1 | sequestosome 1 | -0.0542341 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0538346 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0536179 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0534794 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0534463 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.052928 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0527764 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0523675 |
| EZR | ezrin | -0.0523087 |
| PRKCA | protein kinase C, alpha | -0.0520347 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0516881 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0514908 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0514349 |
| FOXP1 | forkhead box P1 | -0.0508813 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0507052 |
| CUX1 | cut-like homeobox 1 | -0.0505773 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0504 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0496998 |
| NHSL1 | NHS-like 1 | -0.0496298 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0477597 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0474201 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0471972 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0469821 |
| MED13 | mediator complex subunit 13 | -0.0468847 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0467856 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0466881 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0460104 |
| RRBP1 | ribosome binding protein 1 | -0.0454439 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0451919 |
| ERBIN | erbb2 interacting protein | -0.0426912 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0424327 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0420387 |
| FAM13A | family with sequence similarity 13, member A | -0.0420176 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0419322 |
| HMGA2 | high mobility group AT-hook 2 | -0.0417457 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0416967 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0410904 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0409847 |
| FMNL2 | formin-like 2 | -0.0408334 |
| OSMR | oncostatin M receptor | -0.0405249 |
| MACC1 | metastasis associated in colon cancer 1 | -0.039915 |
| CDK13 | cyclin-dependent kinase 13 | -0.0395571 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0390906 |
| MED13L | mediator complex subunit 13-like | -0.0390868 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0390444 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0389529 |
| BCL2L1 | BCL2-like 1 | -0.0386616 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0380244 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0377303 |
| EHBP1 | EH domain binding protein 1 | -0.0369717 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0368574 |
| SEPTIN9 | septin 9 | -0.0368128 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0365583 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0363816 |
| SNX9 | sorting nexin 9 | -0.036306 |
| TCF12 | transcription factor 12 | -0.0360671 |
| ABHD17C | abhydrolase domain containing 17C | -0.0358496 |
| MYO5C | myosin VC | -0.0357619 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0356256 |
| TXNIP | thioredoxin interacting protein | -0.0351784 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0346339 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.034591 |
| USP34 | ubiquitin specific peptidase 34 | -0.0339807 |