| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.160841 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.149604 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.107572 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0942361 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0914587 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0690354 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.061317 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.06071 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0489809 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0458555 |
| CCNL1 | cyclin L1 | 0.0440205 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0432342 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0428591 |
| ASPH | aspartate beta-hydroxylase | 0.0427249 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0396322 |
| RPL4 | ribosomal protein L4 | 0.0394712 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0393765 |
| CANX | calnexin | 0.0365951 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0365793 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0361159 |
| PCBP2 | poly(rC) binding protein 2 | 0.0357259 |
| NCKAP1 | NCK-associated protein 1 | 0.0356994 |
| MATR3 | matrin 3 | 0.0343029 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0342886 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0336768 |
| ARRDC3 | arrestin domain containing 3 | 0.0336764 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0336367 |
| USP3 | ubiquitin specific peptidase 3 | 0.032537 |
| FAM13A | family with sequence similarity 13, member A | 0.0323485 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0317026 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0309136 |
| AHNAK | AHNAK nucleoprotein | 0.0303821 |
| TPM3 | tropomyosin 3 | 0.0300652 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0295188 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.028899 |
| SDC4 | syndecan 4 | 0.0281883 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0279815 |
| CPNE8 | copine VIII | 0.0278845 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.027745 |
| CD83 | CD83 molecule | 0.0274353 |
| TFG | TRK-fused gene | 0.0272124 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0268479 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0265849 |
| ZNF292 | zinc finger protein 292 | 0.0265816 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0262395 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0259185 |
| PLEC | plectin | 0.0258455 |
| PEG10 | paternally expressed 10 | 0.0252993 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0252457 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.025223 |
| PAPOLA | poly(A) polymerase alpha | 0.0252162 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0249657 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0245403 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0245344 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0245039 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0241978 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.024086 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0238906 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0237183 |
| CDC73 | cell division cycle 73 | 0.0236773 |
| NUP58 | nucleoporin 58 | 0.0234627 |
| MSN | moesin | 0.0229209 |
| TXNRD1 | thioredoxin reductase 1 | 0.0227493 |
| DSPP | dentin sialophosphoprotein | 0.0226278 |
| APP | amyloid beta (A4) precursor protein | 0.0223286 |
| RBM33 | RNA binding motif protein 33 | 0.0222159 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0222032 |
| RYBP | RING1 and YY1 binding protein | 0.0218981 |
| MEF2A | myocyte enhancer factor 2A | 0.0213375 |
| YTHDC1 | YTH domain containing 1 | 0.0212993 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0210622 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0209891 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0209511 |
| QKI | QKI, KH domain containing, RNA binding | 0.0207575 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0206645 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0205222 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.020451 |
| TMEM131L | transmembrane 131 like | 0.019841 |
| IPO7 | importin 7 | 0.0197254 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0195776 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0195732 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0195679 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0193326 |
| IRF6 | interferon regulatory factor 6 | 0.019233 |
| LRRC1 | leucine rich repeat containing 1 | 0.0191415 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0189843 |
| NPTN | neuroplastin | 0.018903 |
| MTMR3 | myotubularin related protein 3 | 0.0188438 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0188218 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0184986 |
| SET | SET nuclear proto-oncogene | 0.0184394 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0184203 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0184094 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0183658 |
| TFRC | transferrin receptor | 0.0183156 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0180103 |
| DSCAM | Down syndrome cell adhesion molecule | 0.01792 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0179083 |
| USP12 | ubiquitin specific peptidase 12 | 0.0178744 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0178706 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.228989 |
| TMSB10 | thymosin beta 10 | -0.190362 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.172329 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.163482 |
| PTMA | prothymosin, alpha | -0.155982 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0850627 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0798734 |
| FBXO32 | F-box protein 32 | -0.0759935 |
| S100A6 | S100 calcium binding protein A6 | -0.0753846 |
| CSTB | cystatin B (stefin B) | -0.0742926 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0693227 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0672089 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0655836 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0636767 |
| LMO7 | LIM domain 7 | -0.0631272 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0629592 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.061663 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0612137 |
| S100A10 | S100 calcium binding protein A10 | -0.0603386 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0592199 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0574515 |
| ACTG1 | actin gamma 1 | -0.0567602 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0564412 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0559197 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0556573 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0549415 |
| RPL35A | ribosomal protein L35a | -0.0541164 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0529832 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0525381 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0517695 |
| POTEF | POTE ankyrin domain family, member F | -0.051616 |
| MT2A | metallothionein 2A | -0.0506741 |
| HLA-A | major histocompatibility complex, class I, A | -0.05053 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.050286 |
| ERBIN | erbb2 interacting protein | -0.0486317 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0476413 |
| LAMB3 | laminin, beta 3 | -0.046585 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0453917 |
| TPM4 | tropomyosin 4 | -0.0451155 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0437328 |
| TMEM165 | transmembrane protein 165 | -0.042907 |
| GNAS | GNAS complex locus | -0.0428462 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.042187 |
| RPL34 | ribosomal protein L34 | -0.0419054 |
| MYO1E | myosin IE | -0.0406713 |
| HLA-B | major histocompatibility complex, class I, B | -0.0396011 |
| CCND1 | cyclin D1 | -0.0389037 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0388823 |
| S100A9 | S100 calcium binding protein A9 | -0.0388085 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0386512 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.038435 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0381841 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0378262 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0369692 |
| VIM | vimentin | -0.0369132 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0369074 |
| RRBP1 | ribosome binding protein 1 | -0.0367966 |
| HMGA1 | high mobility group AT-hook 1 | -0.0361678 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0355332 |
| RPLP1 | ribosomal protein, large, P1 | -0.0354576 |
| RPLP2 | ribosomal protein, large, P2 | -0.0354408 |
| EFNA5 | ephrin-A5 | -0.0352316 |
| RPS29 | ribosomal protein S29 | -0.0352311 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0349184 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0348834 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0347746 |
| TMSB4X | thymosin beta 4, X-linked | -0.0342676 |
| TMEM263 | transmembrane protein 263 | -0.034069 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0339907 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0339584 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0337903 |
| UBC | ubiquitin C | -0.0336404 |
| MYO6 | myosin VI | -0.0335253 |
| LMNA | lamin A/C | -0.0333161 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0332293 |
| TXNIP | thioredoxin interacting protein | -0.0328511 |
| CD2AP | CD2-associated protein | -0.0326649 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0324972 |
| RPS13 | ribosomal protein S13 | -0.0323569 |
| RASAL2 | RAS protein activator like 2 | -0.0323254 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0317127 |
| RPS19 | ribosomal protein S19 | -0.0315576 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.031545 |
| RAI14 | retinoic acid induced 14 | -0.0313341 |
| TPI1 | triosephosphate isomerase 1 | -0.0310334 |
| RPS23 | ribosomal protein S23 | -0.0309579 |
| RPL8 | ribosomal protein L8 | -0.030791 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0304011 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0303546 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0303356 |
| CD63 | CD63 molecule | -0.0302991 |
| RPS24 | ribosomal protein S24 | -0.0300761 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0297776 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.029751 |
| MX2 | MX dynamin-like GTPase 2 | -0.0296818 |
| F11R | F11 receptor | -0.02958 |
| CDCP1 | CUB domain containing protein 1 | -0.0295434 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0295313 |
| GOLGB1 | golgin B1 | -0.0291941 |
| RBM47 | RNA binding motif protein 47 | -0.0290522 |