| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine (hydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.333751 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0876424 |
| SPAG9 | sperm associated antigen 9 | 0.0867863 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0584027 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0555273 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0545751 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0520925 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0483178 |
| PCBP2 | poly(rC) binding protein 2 | 0.0481238 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0473114 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0465378 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0460263 |
| DNER | delta/notch-like EGF repeat containing | 0.0452705 |
| OGA | O-GlcNAcase | 0.044675 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.043617 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0406528 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0397462 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.039073 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0355398 |
| WDR43 | WD repeat domain 43 | 0.0351298 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0348781 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0345567 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0344526 |
| PTEN | phosphatase and tensin homolog | 0.0341684 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0333552 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0332055 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0328883 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0312417 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0306414 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0304094 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0301825 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0296866 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0296155 |
| ATAD1 | ATPase family, AAA domain containing 1 | 0.0289465 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0272843 |
| CANX | calnexin | 0.027013 |
| WTAP | Wilms tumor 1 associated protein | 0.0262934 |
| FN1 | fibronectin 1 | 0.0251084 |
| B2M | beta-2-microglobulin | 0.0247879 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0246621 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0245944 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0245618 |
| NUP58 | nucleoporin 58 | 0.0244648 |
| FAM13A | family with sequence similarity 13, member A | 0.0244459 |
| GOLGA4 | golgin A4 | 0.024232 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0241818 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0234828 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0233169 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0232728 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0231175 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0230098 |
| HELZ | helicase with zinc finger | 0.0228537 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0228479 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0228164 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0227984 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0226811 |
| S100A6 | S100 calcium binding protein A6 | 0.0224681 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.0223325 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0222549 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0222372 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0220675 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0220193 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0217938 |
| DENND4A | DENN/MADD domain containing 4A | 0.0217746 |
| RIGI | RNA sensor RIG-I | 0.0217482 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0217301 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0212765 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0212267 |
| CALR | calreticulin | 0.0210986 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0208898 |
| CCNL1 | cyclin L1 | 0.0203519 |
| ACTG1 | actin gamma 1 | 0.0203486 |
| ATF3 | activating transcription factor 3 | 0.0199907 |
| GPHN | gephyrin | 0.0197481 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0195834 |
| FDXR | ferredoxin reductase | 0.0194945 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0193216 |
| ETV3 | ets variant 3 | 0.0192296 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0190916 |
| SDC4 | syndecan 4 | 0.0189176 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0189168 |
| GDF15 | growth differentiation factor 15 | 0.0188994 |
| COPA | coatomer protein complex, subunit alpha | 0.0187168 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0185312 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0184748 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0184167 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0183527 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0182784 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0179842 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.017851 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0178223 |
| VCL | vinculin | 0.0176917 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0176895 |
| JMJD1C | jumonji domain containing 1C | 0.0176705 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.017638 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0174228 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0172963 |
| DENND1A | DENN/MADD domain containing 1A | 0.0172581 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0172507 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0172177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.164809 |
| GDA | guanine deaminase | -0.147372 |
| TXNRD1 | thioredoxin reductase 1 | -0.141552 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1397 |
| ASPH | aspartate beta-hydroxylase | -0.122752 |
| GRAMD1B | GRAM domain containing 1B | -0.120874 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.117241 |
| EFNA5 | ephrin-A5 | -0.107906 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.106766 |
| PDE10A | phosphodiesterase 10A | -0.0957297 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0756459 |
| MYOF | myoferlin | -0.0752886 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.074095 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0733618 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0699715 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0663835 |
| COL5A2 | collagen, type V, alpha 2 | -0.0663652 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0633713 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0619661 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0593393 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0584052 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0581677 |
| CENPF | centromere protein F, 350/400kDa | -0.0580627 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0565174 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0500705 |
| NRCAM | neuronal cell adhesion molecule | -0.0500086 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0494706 |
| MFF | mitochondrial fission factor | -0.0479386 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0478054 |
| CTSC | cathepsin C | -0.0472427 |
| VIM | vimentin | -0.0471386 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0463136 |
| FTL | ferritin, light polypeptide | -0.0462746 |
| PTGR1 | prostaglandin reductase 1 | -0.0462679 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0457124 |
| SMYD3 | SET and MYND domain containing 3 | -0.0440331 |
| RPS2 | ribosomal protein S2 | -0.0438838 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0411713 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0396141 |
| TMSB10 | thymosin beta 10 | -0.0394931 |
| RGS2 | regulator of G-protein signaling 2 | -0.0388844 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0388818 |
| DST | dystonin | -0.0375555 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0371406 |
| FLNB | filamin B, beta | -0.0370478 |
| NEK7 | NIMA-related kinase 7 | -0.0368203 |
| TNPO1 | transportin 1 | -0.0363952 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0349729 |
| MKI67 | marker of proliferation Ki-67 | -0.0340685 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0328862 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0325413 |
| NDRG1 | N-myc downstream regulated 1 | -0.0323945 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0320802 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0311285 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0310696 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0307994 |
| LAMB1 | laminin, beta 1 | -0.0298152 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0290474 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0289584 |
| SRGN | serglycin | -0.0286871 |
| KRT19 | keratin 19, type I | -0.0273138 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0270755 |
| BDNF | brain-derived neurotrophic factor | -0.0268106 |
| PRDX1 | peroxiredoxin 1 | -0.0267653 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0267408 |
| RAB3B | RAB3B, member RAS oncogene family | -0.0260398 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.025497 |
| OSMR | oncostatin M receptor | -0.0254392 |
| MT2A | metallothionein 2A | -0.0247287 |
| RPS24 | ribosomal protein S24 | -0.0245657 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0245129 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0244436 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0241938 |
| PALLD | palladin, cytoskeletal associated protein | -0.0240973 |
| RPS23 | ribosomal protein S23 | -0.0240364 |
| PYGL | phosphorylase, glycogen, liver | -0.0239029 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0236202 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0235684 |
| TBXT | T-box transcription factor T | -0.0233317 |
| RPS6 | ribosomal protein S6 | -0.0222355 |
| ANKRD28 | ankyrin repeat domain 28 | -0.022046 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0219367 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0218794 |
| RTN1 | reticulon 1 | -0.0218721 |
| CDK6 | cyclin-dependent kinase 6 | -0.0214789 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0214097 |
| RPL31 | ribosomal protein L31 | -0.0213828 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0213645 |
| CTSL | cathepsin L | -0.0213632 |
| EZR | ezrin | -0.0213403 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0211776 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0208826 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0199417 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0192758 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0192143 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0190305 |
| CLTC | clathrin, heavy chain (Hc) | -0.0189851 |
| ATXN1 | ataxin 1 | -0.0188971 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0187703 |
| ETV1 | ets variant 1 | -0.018606 |
