Cytarabine (hydrochloride)_NCI-H596 Gene Set
Genes
52 genes differentially expressed following the Cytarabine (hydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
FN1
|
fibronectin 1
|
0.175355
|
|
GPC6
|
glypican 6
|
0.164833
|
|
PITPNC1
|
phosphatidylinositol transfer protein, cytoplasmic 1
|
0.13826
|
|
ESYT2
|
extended synaptotagmin-like protein 2
|
0.132868
|
|
UACA
|
uveal autoantigen with coiled-coil domains and ankyrin repeats
|
0.131766
|
|
MDM2
|
MDM2 proto-oncogene, E3 ubiquitin protein ligase
|
0.130538
|
|
MAGI2
|
membrane associated guanylate kinase, WW and PDZ domain containing 2
|
0.120875
|
|
PDE10A
|
phosphodiesterase 10A
|
0.0891331
|
|
AKAP12
|
A kinase (PRKA) anchor protein 12
|
0.0779093
|
|
TANC1
|
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
|
0.0694811
|
|
IMMP2L
|
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
|
0.0660832
|
|
PRELID2
|
PRELI domain containing 2
|
0.0643954
|
|
COPA
|
coatomer protein complex, subunit alpha
|
0.0642957
|
|
NAMPT
|
nicotinamide phosphoribosyltransferase
|
0.0631554
|
|
FAT1
|
FAT atypical cadherin 1
|
0.060259
|
|
SMAD3
|
SMAD family member 3
|
0.0601588
|
|
PTK2
|
protein tyrosine kinase 2
|
0.0557232
|
|
P4HB
|
prolyl 4-hydroxylase, beta polypeptide
|
0.0557142
|
|
FAM13A
|
family with sequence similarity 13, member A
|
0.0386114
|
|
ATXN1
|
ataxin 1
|
0.0302055
|
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase
|
0.0276954
|
|
PHF14
|
PHD finger protein 14
|
0.0251243
|
|
ZNF638
|
zinc finger protein 638
|
0.0243672
|
|
VIM
|
vimentin
|
0.0192916
|
|
RBPJ
|
recombination signal binding protein for immunoglobulin kappa J region
|
0.0145969
|
|
AGAP1
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
|
0.0108328
|
|
SPAG9
|
sperm associated antigen 9
|
0.00976172
|
|
TPT1
|
tumor protein, translationally-controlled 1
|
3.12886E-4
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NDRG1
|
N-myc downstream regulated 1
|
-0.192293
|
|
ITGB1
|
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
|
-0.178088
|
|
LDHA
|
lactate dehydrogenase A
|
-0.136444
|
|
PALM2AKAP2
|
PALM2 and AKAP2 fusion
|
-0.130516
|
|
HSP90B1
|
heat shock protein 90kDa beta (Grp94), member 1
|
-0.112054
|
|
PGK1
|
phosphoglycerate kinase 1
|
-0.106679
|
|
RPL26
|
ribosomal protein L26
|
-0.0905992
|
|
QKI
|
QKI, KH domain containing, RNA binding
|
-0.0862522
|
|
B2M
|
beta-2-microglobulin
|
-0.0820474
|
|
HSP90AB1
|
heat shock protein 90kDa alpha (cytosolic), class B member 1
|
-0.0784473
|
|
GBE1
|
glucan (1,4-alpha-), branching enzyme 1
|
-0.0660109
|
|
FNDC3B
|
fibronectin type III domain containing 3B
|
-0.0503591
|
|
PARD3
|
par-3 family cell polarity regulator
|
-0.0486831
|
|
MMAB
|
methylmalonic aciduria (cobalamin deficiency) cblB type
|
-0.0411984
|
|
IGFBP5
|
insulin-like growth factor binding protein 5
|
-0.0349797
|
|
KMT2E
|
lysine (K)-specific methyltransferase 2E
|
-0.0234889
|
|
MT2A
|
metallothionein 2A
|
-0.0231938
|
|
ZNF292
|
zinc finger protein 292
|
-0.0209456
|
|
NPAS2
|
neuronal PAS domain protein 2
|
-0.0179432
|
|
KCNMA1
|
potassium channel, calcium activated large conductance subfamily M alpha, member 1
|
-0.0152732
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-0.0104743
|
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1
|
-0.00527686
|
|
PDE4D
|
phosphodiesterase 4D, cAMP-specific
|
-0.00333613
|
|
ENO1
|
enolase 1, (alpha)
|
-0.00293303
|
