| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.0713427 |
| ZNF292 | zinc finger protein 292 | 0.0552227 |
| PCBP2 | poly(rC) binding protein 2 | 0.0480962 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0464895 |
| HDAC9 | histone deacetylase 9 | 0.0444539 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0440896 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0420087 |
| DST | dystonin | 0.0386576 |
| WDR43 | WD repeat domain 43 | 0.0378908 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0378105 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0374236 |
| NCKAP1 | NCK-associated protein 1 | 0.0361027 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0347213 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0330705 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0310509 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0308002 |
| RBM33 | RNA binding motif protein 33 | 0.0291388 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0286248 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0285909 |
| YAP1 | Yes-associated protein 1 | 0.0278961 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0276074 |
| CCNL1 | cyclin L1 | 0.0273739 |
| GASK1B | golgi associated kinase 1B | 0.0271869 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0269438 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0267298 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0266115 |
| CFL2 | cofilin 2 (muscle) | 0.0259595 |
| MEMO1 | mediator of cell motility 1 | 0.0256905 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0256658 |
| KIF1B | kinesin family member 1B | 0.0256198 |
| DMXL1 | Dmx-like 1 | 0.0255244 |
| MB21D2 | Mab-21 domain containing 2 | 0.0253701 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0252708 |
| CCNY | cyclin Y | 0.0250377 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0250085 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0249904 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0249793 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0248496 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0246786 |
| USP12 | ubiquitin specific peptidase 12 | 0.0245332 |
| ITGAV | integrin, alpha V | 0.0243762 |
| XPO1 | exportin 1 | 0.0243127 |
| ENAH | enabled homolog (Drosophila) | 0.0242462 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0241587 |
| SPAG9 | sperm associated antigen 9 | 0.0241084 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0237219 |
| MTF2 | metal response element binding transcription factor 2 | 0.0233613 |
| FBXO11 | F-box protein 11 | 0.0230589 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0230511 |
| NTM | neurotrimin | 0.0230242 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0228806 |
| USP3 | ubiquitin specific peptidase 3 | 0.0227973 |
| MYO10 | myosin X | 0.0225697 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0225407 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0224073 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0223281 |
| SYT1 | synaptotagmin I | 0.0218839 |
| TPM3 | tropomyosin 3 | 0.021868 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0216685 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0216215 |
| APP | amyloid beta (A4) precursor protein | 0.0215658 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0212725 |
| POTEF | POTE ankyrin domain family, member F | 0.021175 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0210886 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0209387 |
| EMC1 | ER membrane protein complex subunit 1 | 0.0208591 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0206446 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0205898 |
| RHEB | Ras homolog enriched in brain | 0.0205406 |
| CCDC88A | coiled-coil domain containing 88A | 0.0202675 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0202505 |
| ABI1 | abl-interactor 1 | 0.0197974 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.019711 |
| PDGFC | platelet derived growth factor C | 0.0197096 |
| FAM168A | family with sequence similarity 168, member A | 0.0195959 |
| NPTN | neuroplastin | 0.0194393 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0192678 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.0191039 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0189034 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0188885 |
| PDS5B | PDS5 cohesin associated factor B | 0.0188774 |
| SERTAD2 | SERTA domain containing 2 | 0.0188516 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0187688 |
| ZNF451 | zinc finger protein 451 | 0.0187357 |
| XPO4 | exportin 4 | 0.0186388 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0186225 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0185887 |
| NBAS | neuroblastoma amplified sequence | 0.0185858 |
| RBM20 | RNA binding motif protein 20 | 0.0185316 |
| AFAP1 | actin filament associated protein 1 | 0.0184968 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0184133 |
| CDC73 | cell division cycle 73 | 0.0183968 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0183669 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0183538 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0182315 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0182183 |
| UBE3A | ubiquitin protein ligase E3A | 0.0180404 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0179842 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.017938 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0178587 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.282191 |
| TMSB10 | thymosin beta 10 | -0.153692 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.136151 |
| PTMA | prothymosin, alpha | -0.134253 |
| COL11A1 | collagen, type XI, alpha 1 | -0.120151 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116674 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110528 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.10113 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0973688 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0965709 |
| CADM2 | cell adhesion molecule 2 | -0.0956542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0881346 |
| RPLP1 | ribosomal protein, large, P1 | -0.0841649 |
| GNAS | GNAS complex locus | -0.0818486 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0817987 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0745474 |
| RPS6 | ribosomal protein S6 | -0.0743937 |
| RPS8 | ribosomal protein S8 | -0.0731634 |
| MKI67 | marker of proliferation Ki-67 | -0.071575 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0663337 |
| RPS16 | ribosomal protein S16 | -0.0625385 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0614513 |
| GPC3 | glypican 3 | -0.057251 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0568477 |
| H1-0 | H1.0 linker histone | -0.0546433 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0541784 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0529514 |
| PCDH9 | protocadherin 9 | -0.0525989 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0523599 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0499284 |
| FOXP2 | forkhead box P2 | -0.0491847 |
| MEIS2 | Meis homeobox 2 | -0.0491223 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0474788 |
| CAVIN1 | caveolae associated protein 1 | -0.0473428 |
| RPL12 | ribosomal protein L12 | -0.0466479 |
| PEG10 | paternally expressed 10 | -0.0463916 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0449384 |
| RPS24 | ribosomal protein S24 | -0.0434159 |
| PFN1 | profilin 1 | -0.0433689 |
| RPS21 | ribosomal protein S21 | -0.0431923 |
| RPL35A | ribosomal protein L35a | -0.0422746 |
| RPS19 | ribosomal protein S19 | -0.0414762 |
| SRP72 | signal recognition particle 72kDa | -0.0408668 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0406204 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0402819 |
| CALR | calreticulin | -0.0396025 |
| CENPF | centromere protein F, 350/400kDa | -0.039071 |
| HMGB1 | high mobility group box 1 | -0.0389259 |
| RPL34 | ribosomal protein L34 | -0.0387864 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0387343 |
| RPLP0 | ribosomal protein, large, P0 | -0.0382271 |
| COL1A2 | collagen, type I, alpha 2 | -0.0375241 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0368965 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0368154 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0365309 |
| CKAP2 | cytoskeleton associated protein 2 | -0.036036 |
| RPL11 | ribosomal protein L11 | -0.0359742 |
| FTL | ferritin, light polypeptide | -0.0357637 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0342426 |
| RPL19 | ribosomal protein L19 | -0.0337775 |
| RACK1 | receptor for activated C kinase 1 | -0.0335845 |
| KIF4A | kinesin family member 4A | -0.0335112 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0335075 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0334173 |
| TPR | translocated promoter region, nuclear basket protein | -0.0332391 |
| GOLGA4 | golgin A4 | -0.0322451 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0318672 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0311784 |
| RPL38 | ribosomal protein L38 | -0.0311229 |
| MTDH | metadherin | -0.0309057 |
| RPS3 | ribosomal protein S3 | -0.030779 |
| SERF2 | small EDRK-rich factor 2 | -0.030691 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0303919 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0303178 |
| MAP4 | microtubule-associated protein 4 | -0.0302511 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0302219 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0300917 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0300351 |
| ACTN4 | actinin, alpha 4 | -0.0298547 |
| YBX1 | Y box binding protein 1 | -0.0295544 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0290915 |
| RPLP2 | ribosomal protein, large, P2 | -0.0285372 |
| DEK | DEK proto-oncogene | -0.0282803 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0282801 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0282706 |
| RPS27 | ribosomal protein S27 | -0.0282388 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0282231 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0279986 |
| S100A10 | S100 calcium binding protein A10 | -0.027773 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0277274 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0275085 |
| RPL27A | ribosomal protein L27a | -0.0273659 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0271467 |
| RPL28 | ribosomal protein L28 | -0.0268392 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0268265 |
| METAP2 | methionyl aminopeptidase 2 | -0.0267504 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0267465 |
| LRRC4C | leucine rich repeat containing 4C | -0.0267375 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0266434 |
| SGO2 | shugoshin 2 | -0.0266179 |
