| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.132381 |
| DIAPH3 | diaphanous-related formin 3 | 0.102119 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0946381 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0817933 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0802387 |
| ZNF292 | zinc finger protein 292 | 0.0681131 |
| CALD1 | caldesmon 1 | 0.0680538 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0591887 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0590005 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0579873 |
| RAD51B | RAD51 paralog B | 0.0572055 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0564954 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0561133 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0557822 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0538754 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0533144 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0530032 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0527194 |
| GOLGA4 | golgin A4 | 0.0527114 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.052265 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0508732 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0483311 |
| HDAC9 | histone deacetylase 9 | 0.0482129 |
| NUP58 | nucleoporin 58 | 0.047415 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0468857 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0453006 |
| DENND1A | DENN/MADD domain containing 1A | 0.0451311 |
| HELLS | helicase, lymphoid-specific | 0.0438466 |
| ATP13A3 | ATPase type 13A3 | 0.0427692 |
| ZNF841 | zinc finger protein 841 | 0.0424215 |
| CCNL1 | cyclin L1 | 0.042183 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0404791 |
| E2F7 | E2F transcription factor 7 | 0.0395508 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0387282 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0382253 |
| RRM2 | ribonucleotide reductase M2 | 0.0381331 |
| ZNF654 | zinc finger protein 654 | 0.0379061 |
| MEF2A | myocyte enhancer factor 2A | 0.0378418 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0375771 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0373757 |
| BBX | bobby sox homolog (Drosophila) | 0.0357514 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0356719 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0350757 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0349875 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.0343919 |
| FANCI | Fanconi anemia, complementation group I | 0.0342292 |
| SETD5 | SET domain containing 5 | 0.0341158 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.033737 |
| RPS12 | ribosomal protein S12 | 0.0333141 |
| HMGB2 | high mobility group box 2 | 0.0330659 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0330159 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0328186 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0328183 |
| WDR43 | WD repeat domain 43 | 0.0322525 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0320786 |
| CENPF | centromere protein F, 350/400kDa | 0.0315943 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0314625 |
| RLF | rearranged L-myc fusion | 0.0314512 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0314065 |
| TMF1 | TATA element modulatory factor 1 | 0.0312525 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0305398 |
| RPL35A | ribosomal protein L35a | 0.0301825 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0301537 |
| CENPP | centromere protein P | 0.0299736 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0299482 |
| TPM3 | tropomyosin 3 | 0.0299263 |
| PCM1 | pericentriolar material 1 | 0.0298154 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0296438 |
| DEK | DEK proto-oncogene | 0.0293989 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0293292 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0292521 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0291498 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0290268 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0287976 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0286747 |
| B2M | beta-2-microglobulin | 0.0286632 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0285548 |
| BCL2L1 | BCL2-like 1 | 0.0284841 |
| GOLGA2 | golgin A2 | 0.0284211 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0283989 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0281399 |
| SDC4 | syndecan 4 | 0.0281168 |
| CCDC14 | coiled-coil domain containing 14 | 0.0280237 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0279839 |
| RPS3 | ribosomal protein S3 | 0.0278919 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0277104 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0271146 |
| TPR | translocated promoter region, nuclear basket protein | 0.027058 |
| YEATS2 | YEATS domain containing 2 | 0.0268685 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0268497 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | 0.0268436 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0266543 |
| FNIP1 | folliculin interacting protein 1 | 0.0266237 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0265822 |
| MCM8 | minichromosome maintenance complex component 8 | 0.0264707 |
| FKBP15 | FK506 binding protein 15, 133kDa | 0.0263589 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0263249 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0257221 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0256699 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0255245 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.176187 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.17595 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.15024 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.120294 |
| UBC | ubiquitin C | -0.119839 |
| STC1 | stanniocalcin 1 | -0.115287 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10351 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0944993 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.086494 |
| JUN | jun proto-oncogene | -0.0807142 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0776226 |
| UPP1 | uridine phosphorylase 1 | -0.0762804 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0731006 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0715762 |
| NAV3 | neuron navigator 3 | -0.0652969 |
| MT2A | metallothionein 2A | -0.0640865 |
| AHNAK | AHNAK nucleoprotein | -0.0596669 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0587839 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0569228 |
| RPS27A | ribosomal protein S27a | -0.056295 |
| POTEF | POTE ankyrin domain family, member F | -0.054985 |
| TMSB10 | thymosin beta 10 | -0.0545828 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0545088 |
| TXNRD1 | thioredoxin reductase 1 | -0.0532938 |
| HMGA1 | high mobility group AT-hook 1 | -0.0524962 |
| PKM | pyruvate kinase, muscle | -0.0482121 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0481107 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0459589 |
| G0S2 | G0/G1 switch 2 | -0.0456733 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0441553 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0434672 |
| RPL8 | ribosomal protein L8 | -0.0415273 |
| ENO1 | enolase 1, (alpha) | -0.0405035 |
| NAV2 | neuron navigator 2 | -0.0389285 |
| SGMS2 | sphingomyelin synthase 2 | -0.0384737 |
| RPS24 | ribosomal protein S24 | -0.0382558 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0382368 |
| EGR1 | early growth response 1 | -0.0370582 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0359368 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0349766 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0348171 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0342136 |
| RPLP1 | ribosomal protein, large, P1 | -0.0341043 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0340817 |
| FTL | ferritin, light polypeptide | -0.0340258 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0322776 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0308321 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0300701 |
| RPL32 | ribosomal protein L32 | -0.0291838 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0291019 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.0283772 |
| GLRX | glutaredoxin (thioltransferase) | -0.0281642 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0277368 |
| RPL12 | ribosomal protein L12 | -0.0274045 |
| CORO1C | coronin, actin binding protein, 1C | -0.0271061 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0269899 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0268299 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | -0.0266398 |
| FLNA | filamin A, alpha | -0.0258914 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0258289 |
| CD44 | CD44 molecule (Indian blood group) | -0.025706 |
| KLF10 | Kruppel-like factor 10 | -0.0251888 |
| LDHA | lactate dehydrogenase A | -0.0251552 |
| FHL2 | four and a half LIM domains 2 | -0.024848 |
| ACACA | acetyl-CoA carboxylase alpha | -0.024543 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0244963 |
| RGS4 | regulator of G-protein signaling 4 | -0.0242235 |
| EFNB2 | ephrin-B2 | -0.0240476 |
| FAM13A | family with sequence similarity 13, member A | -0.0233245 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0232933 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0227369 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0224603 |
| RGMB | repulsive guidance molecule family member b | -0.0223598 |
| JMJD1C | jumonji domain containing 1C | -0.0218747 |
| MCL1 | myeloid cell leukemia 1 | -0.0217856 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0216672 |
| RPS15 | ribosomal protein S15 | -0.021618 |
| ACTN1 | actinin, alpha 1 | -0.0214543 |
| TOP1 | topoisomerase (DNA) I | -0.0210987 |
| SCFD2 | sec1 family domain containing 2 | -0.0210834 |
| EMP1 | epithelial membrane protein 1 | -0.0209017 |
| RPL31 | ribosomal protein L31 | -0.0205513 |
| RPS5 | ribosomal protein S5 | -0.0205377 |
| RPS23 | ribosomal protein S23 | -0.0205241 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0205169 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0202969 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0202656 |
| HMGA2 | high mobility group AT-hook 2 | -0.0199057 |
| RPL23 | ribosomal protein L23 | -0.0196708 |
| TEX10 | testis expressed 10 | -0.0195169 |
| CDK17 | cyclin-dependent kinase 17 | -0.0192588 |
| CD68 | CD68 molecule | -0.019227 |
| MTDH | metadherin | -0.0185393 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0185171 |
| MX2 | MX dynamin-like GTPase 2 | -0.0184822 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0184137 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0181463 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0177793 |
| LAMB3 | laminin, beta 3 | -0.0176724 |
| RPL6 | ribosomal protein L6 | -0.0172996 |
