| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0972515 |
| ZNF292 | zinc finger protein 292 | 0.0907442 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0653021 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.060583 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0573576 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0569739 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0564108 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0533303 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.052974 |
| XPO1 | exportin 1 | 0.0508146 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.046443 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0458756 |
| GOLGA4 | golgin A4 | 0.0443592 |
| SDC4 | syndecan 4 | 0.0433129 |
| FAM13A | family with sequence similarity 13, member A | 0.0429324 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0426571 |
| STC1 | stanniocalcin 1 | 0.0426263 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0424652 |
| CD109 | CD109 molecule | 0.0417373 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0411088 |
| DSCAM | Down syndrome cell adhesion molecule | 0.040544 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0396059 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0386147 |
| TFG | TRK-fused gene | 0.0385286 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.038336 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0360404 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0355778 |
| PCBP2 | poly(rC) binding protein 2 | 0.0354143 |
| NBAS | neuroblastoma amplified sequence | 0.0353352 |
| YEATS2 | YEATS domain containing 2 | 0.0352711 |
| RLF | rearranged L-myc fusion | 0.035257 |
| MSN | moesin | 0.034951 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0349015 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0347859 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0344843 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0338245 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0336535 |
| SUCO | SUN domain containing ossification factor | 0.0336066 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0333815 |
| CCNL1 | cyclin L1 | 0.0333642 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0330102 |
| HELZ | helicase with zinc finger | 0.0323761 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0321593 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0318843 |
| PGK1 | phosphoglycerate kinase 1 | 0.0318062 |
| ATP13A3 | ATPase type 13A3 | 0.0316572 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0312543 |
| OGA | O-GlcNAcase | 0.0310703 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0306941 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0302288 |
| SMAD3 | SMAD family member 3 | 0.0296222 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0296154 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0293691 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0293233 |
| RBM39 | RNA binding motif protein 39 | 0.0292529 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.028905 |
| RYBP | RING1 and YY1 binding protein | 0.028811 |
| NCKAP1 | NCK-associated protein 1 | 0.0285954 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0285615 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0284674 |
| DIAPH3 | diaphanous-related formin 3 | 0.0284546 |
| ACTN4 | actinin, alpha 4 | 0.0284291 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0281497 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0276697 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.027452 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.027404 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0273793 |
| NUP58 | nucleoporin 58 | 0.0273389 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0272793 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0268827 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0267505 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0267373 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0266018 |
| ANLN | anillin, actin binding protein | 0.0263739 |
| CDC73 | cell division cycle 73 | 0.0263597 |
| WTAP | Wilms tumor 1 associated protein | 0.0262157 |
| RTN4 | reticulon 4 | 0.0260277 |
| IFI44 | interferon-induced protein 44 | 0.0259699 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0258831 |
| ARRDC3 | arrestin domain containing 3 | 0.0257138 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0254537 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0252981 |
| COPA | coatomer protein complex, subunit alpha | 0.025245 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0251425 |
| ZNF654 | zinc finger protein 654 | 0.0249855 |
| SPAG9 | sperm associated antigen 9 | 0.0246609 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0246434 |
| FLNB | filamin B, beta | 0.0242017 |
| YME1L1 | YME1-like 1 ATPase | 0.024013 |
| ZNF148 | zinc finger protein 148 | 0.0238667 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0238387 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0237722 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.023745 |
| NPTN | neuroplastin | 0.0236179 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0233717 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0230992 |
| MEF2A | myocyte enhancer factor 2A | 0.0230734 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0229619 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0229208 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0228247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.353692 |
| FTL | ferritin, light polypeptide | -0.137748 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.112758 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.109485 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109192 |
| HLA-B | major histocompatibility complex, class I, B | -0.10721 |
| COL1A2 | collagen, type I, alpha 2 | -0.100972 |
| TMSB10 | thymosin beta 10 | -0.0954616 |
| FN1 | fibronectin 1 | -0.0952237 |
| B2M | beta-2-microglobulin | -0.0913935 |
| COL1A1 | collagen, type I, alpha 1 | -0.0893311 |
| NDRG1 | N-myc downstream regulated 1 | -0.0767485 |
| MT2A | metallothionein 2A | -0.075954 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0711689 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0637597 |
| EGR1 | early growth response 1 | -0.0561147 |
| PTMA | prothymosin, alpha | -0.0556614 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0514686 |
| HLA-A | major histocompatibility complex, class I, A | -0.0506808 |
| TPM4 | tropomyosin 4 | -0.0482579 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0456136 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0453678 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0453105 |
| TPM1 | tropomyosin 1 (alpha) | -0.043931 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.041482 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390031 |
| CDH13 | cadherin 13 | -0.0377079 |
| RPL35A | ribosomal protein L35a | -0.0376944 |
| CALR | calreticulin | -0.0375382 |
| RPS8 | ribosomal protein S8 | -0.0372581 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0371652 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0371049 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0361758 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0343979 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0343764 |
| S100A10 | S100 calcium binding protein A10 | -0.0341552 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0336936 |
| H1-0 | H1.0 linker histone | -0.0331106 |
| RRBP1 | ribosome binding protein 1 | -0.0320782 |
| RPS6 | ribosomal protein S6 | -0.0315933 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0312937 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0310736 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0309379 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0309335 |
| NAV1 | neuron navigator 1 | -0.0308891 |
| FRMD4A | FERM domain containing 4A | -0.0304155 |
| RPL37A | ribosomal protein L37a | -0.029938 |
| TPI1 | triosephosphate isomerase 1 | -0.0289133 |
| ENO1 | enolase 1, (alpha) | -0.0280931 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0278575 |
| TGFB1 | transforming growth factor, beta 1 | -0.0276938 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0273749 |
| RPL31 | ribosomal protein L31 | -0.0272997 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0272095 |
| S100A9 | S100 calcium binding protein A9 | -0.0271719 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0269324 |
| RPL34 | ribosomal protein L34 | -0.0267951 |
| RPLP2 | ribosomal protein, large, P2 | -0.0265053 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0258919 |
| S100A6 | S100 calcium binding protein A6 | -0.0250927 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0250846 |
| RPS19 | ribosomal protein S19 | -0.0249949 |
| SERF2 | small EDRK-rich factor 2 | -0.0246377 |
| IER3 | immediate early response 3 | -0.0244711 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0243785 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0240226 |
| RPS25 | ribosomal protein S25 | -0.0235311 |
| RPL36 | ribosomal protein L36 | -0.0233904 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0231592 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0231501 |
| CST3 | cystatin C | -0.0229633 |
| RPS13 | ribosomal protein S13 | -0.0224163 |
| RPS29 | ribosomal protein S29 | -0.0224154 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0223169 |
| RPL28 | ribosomal protein L28 | -0.0221524 |
| HLA-C | major histocompatibility complex, class I, C | -0.0221213 |
| PKM | pyruvate kinase, muscle | -0.0220626 |
| CAVIN1 | caveolae associated protein 1 | -0.0220277 |
| COL5A3 | collagen, type V, alpha 3 | -0.0219889 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0219519 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0216901 |
| LMNA | lamin A/C | -0.0214341 |
| INTS6 | integrator complex subunit 6 | -0.0213708 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0209602 |
| SHISA5 | shisa family member 5 | -0.0207766 |
| RPS21 | ribosomal protein S21 | -0.020406 |
| HMGA2 | high mobility group AT-hook 2 | -0.0202713 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0201284 |
| LOX | lysyl oxidase | -0.0198918 |
| ATF4 | activating transcription factor 4 | -0.0197566 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0196304 |
| NRP1 | neuropilin 1 | -0.0194877 |
| RPS3 | ribosomal protein S3 | -0.0193099 |
| RPS17 | ribosomal protein S17 | -0.0192697 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0190435 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0188969 |
| S100A11 | S100 calcium binding protein A11 | -0.0186214 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0186092 |
| RPL12 | ribosomal protein L12 | -0.0185905 |
| MAP4 | microtubule-associated protein 4 | -0.0183924 |
