| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cytarabine (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT8 | keratin 8, type II | 0.103401 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0742874 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0724028 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0711216 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0682748 |
| ZNF292 | zinc finger protein 292 | 0.0661938 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0635382 |
| ACTG1 | actin gamma 1 | 0.0601135 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0596262 |
| NCKAP1 | NCK-associated protein 1 | 0.0577137 |
| SDC4 | syndecan 4 | 0.0558179 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0554765 |
| MED13L | mediator complex subunit 13-like | 0.0542684 |
| ANKRD11 | ankyrin repeat domain 11 | 0.053114 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0526438 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0525945 |
| MATR3 | matrin 3 | 0.0503958 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0477662 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0473057 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0472706 |
| RBM39 | RNA binding motif protein 39 | 0.0471849 |
| UBQLN1 | ubiquilin 1 | 0.0471086 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0469775 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0469461 |
| CCNL1 | cyclin L1 | 0.0468683 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0462012 |
| DSPP | dentin sialophosphoprotein | 0.0451333 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0451212 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0450898 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0449585 |
| PLEC | plectin | 0.0442951 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0442604 |
| RBM33 | RNA binding motif protein 33 | 0.04412 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0437614 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0433559 |
| MEF2A | myocyte enhancer factor 2A | 0.0431333 |
| PCBP2 | poly(rC) binding protein 2 | 0.0422566 |
| MTMR3 | myotubularin related protein 3 | 0.0413569 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0413427 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0405169 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0395192 |
| SUCO | SUN domain containing ossification factor | 0.0393661 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0390113 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0389771 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0387317 |
| TFG | TRK-fused gene | 0.0383231 |
| YAP1 | Yes-associated protein 1 | 0.0382601 |
| TUFT1 | tuftelin 1 | 0.0375595 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0374178 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.037295 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0372824 |
| USP3 | ubiquitin specific peptidase 3 | 0.0371397 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0369273 |
| SET | SET nuclear proto-oncogene | 0.0365417 |
| PTK2 | protein tyrosine kinase 2 | 0.0362764 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0352737 |
| OLA1 | Obg-like ATPase 1 | 0.0349028 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0345915 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0344924 |
| TPM3 | tropomyosin 3 | 0.034483 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.033835 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0338183 |
| OGA | O-GlcNAcase | 0.0336613 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0336515 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0334209 |
| RHEB | Ras homolog enriched in brain | 0.0333232 |
| RPS6 | ribosomal protein S6 | 0.0332126 |
| SPAG9 | sperm associated antigen 9 | 0.0326252 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0324414 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0321532 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0316926 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0316652 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0316209 |
| DIAPH1 | diaphanous-related formin 1 | 0.0314456 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0312635 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0311478 |
| RPL4 | ribosomal protein L4 | 0.0303954 |
| GOLGA4 | golgin A4 | 0.0303604 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.029812 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0295959 |
| HELLS | helicase, lymphoid-specific | 0.0295428 |
| HMGB2 | high mobility group box 2 | 0.0289699 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0287086 |
| DIDO1 | death inducer-obliterator 1 | 0.0286392 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0285122 |
| CRY1 | cryptochrome circadian clock 1 | 0.0284881 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0283698 |
| AFDN | afadin, adherens junction formation factor | 0.0283025 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0282386 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0281259 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0281043 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0278697 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0277478 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0276242 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0275999 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0274 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0273187 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0272977 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0271231 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0271085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | -0.134159 |
| EGR1 | early growth response 1 | -0.0938814 |
| EZR | ezrin | -0.0852246 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0845341 |
| TMSB10 | thymosin beta 10 | -0.079842 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0773574 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0725077 |
| PTMA | prothymosin, alpha | -0.0712014 |
| EHBP1 | EH domain binding protein 1 | -0.0697131 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.067073 |
| FTL | ferritin, light polypeptide | -0.0641717 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0629948 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0624221 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0585887 |
| SLC38A1 | solute carrier family 38, member 1 | -0.056808 |
| H1-0 | H1.0 linker histone | -0.0559005 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0542983 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.050818 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.048373 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0481196 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0467081 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0465925 |
| CLDN4 | claudin 4 | -0.0444744 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0438715 |
| CUX1 | cut-like homeobox 1 | -0.0412626 |
| SVIL | supervillin | -0.0411947 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.041135 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0408451 |
| NEBL | nebulette | -0.0402458 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0400219 |
| LDHA | lactate dehydrogenase A | -0.038874 |
| NDRG1 | N-myc downstream regulated 1 | -0.0383782 |
| RPL18 | ribosomal protein L18 | -0.0380814 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0375044 |
| S100A6 | S100 calcium binding protein A6 | -0.0351577 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0351207 |
| NFIA | nuclear factor I/A | -0.0348494 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0346798 |
| KRT19 | keratin 19, type I | -0.0344247 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.033868 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0333266 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0332366 |
| TMEM123 | transmembrane protein 123 | -0.0330975 |
| PLSCR1 | phospholipid scramblase 1 | -0.032622 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0323934 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0320463 |
| CENPF | centromere protein F, 350/400kDa | -0.0313904 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.030796 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.030788 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0307526 |
| KRT18 | keratin 18, type I | -0.0304535 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0300842 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0297399 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0296479 |
| ADNP | activity-dependent neuroprotector homeobox | -0.029551 |
| RNF43 | ring finger protein 43 | -0.0294336 |
| CADPS | Ca++-dependent secretion activator | -0.0287414 |
| RPS24 | ribosomal protein S24 | -0.0277438 |
| EDN1 | endothelin 1 | -0.0275991 |
| FAT1 | FAT atypical cadherin 1 | -0.0275425 |
| IER3 | immediate early response 3 | -0.027506 |
| PERP | PERP, TP53 apoptosis effector | -0.0273326 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0271191 |
| RSF1 | remodeling and spacing factor 1 | -0.026829 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0267411 |
| MIDN | midnolin | -0.0266268 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0264493 |
| TUBB | tubulin, beta class I | -0.0262412 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0261886 |
| ETV6 | ets variant 6 | -0.0260833 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0259561 |
| BCL2L1 | BCL2-like 1 | -0.0257929 |
| FRMD5 | FERM domain containing 5 | -0.0257709 |
| PHF14 | PHD finger protein 14 | -0.0254881 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0254709 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0253554 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.025124 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0249168 |
| TRIM56 | tripartite motif containing 56 | -0.0248356 |
| SON | SON DNA binding protein | -0.0247619 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.02475 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0247319 |
| NF1 | neurofibromin 1 | -0.0244881 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0243057 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0241875 |
| MYOF | myoferlin | -0.0239522 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0238822 |
| CTSD | cathepsin D | -0.0238769 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0237518 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0234809 |
| ATXN2 | ataxin 2 | -0.0233026 |
| FNBP4 | formin binding protein 4 | -0.023265 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0232104 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0230796 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0229876 |
| THOC2 | THO complex 2 | -0.0229092 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | -0.0228633 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0228579 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0227046 |
| EPCAM | epithelial cell adhesion molecule | -0.0226503 |