Cytarabine (hydrochloride)_SW480 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Cytarabine (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Cytarabine (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NAV2 neuron navigator 2 0.102716
INTS6 integrator complex subunit 6 0.0691923
VCL vinculin 0.0686569
SDK1 sidekick cell adhesion molecule 1 0.0635237
ASPH aspartate beta-hydroxylase 0.060915
CDH13 cadherin 13 0.0597954
RAD51B RAD51 paralog B 0.0556207
MACF1 microtubule-actin crosslinking factor 1 0.049118
ANO1 anoctamin 1, calcium activated chloride channel 0.0485476
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0452679
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0437942
DST dystonin 0.0431499
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0430592
FNDC3B fibronectin type III domain containing 3B 0.0410803
BACE2 beta-site APP-cleaving enzyme 2 0.0405607
FLNB filamin B, beta 0.0399606
MRPS6 mitochondrial ribosomal protein S6 0.0386018
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0383445
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.038265
AKAP12 A kinase (PRKA) anchor protein 12 0.0372716
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0337489
KRT8 keratin 8, type II 0.0332237
RRM2 ribonucleotide reductase M2 0.0329216
LRMDA leucine rich melanocyte differentiation associated 0.0323294
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0318931
FNIP1 folliculin interacting protein 1 0.031218
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0311184
MYH9 myosin, heavy chain 9, non-muscle 0.0310651
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0307661
ATAD2 ATPase family, AAA domain containing 2 0.0303712
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0296887
PCBP2 poly(rC) binding protein 2 0.029485
UTRN utrophin 0.0292138
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0287686
SDC4 syndecan 4 0.028197
ZCCHC7 zinc finger, CCHC domain containing 7 0.0280665
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0277669
BIRC6 baculoviral IAP repeat containing 6 0.0275616
EXOC4 exocyst complex component 4 0.0275312
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0274064
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0271139
SAMD4A sterile alpha motif domain containing 4A 0.0265135
ETNK1 ethanolamine kinase 1 0.0260119
ITPRID2 ITPR interacting domain containing 2 0.0253422
ITCH itchy E3 ubiquitin protein ligase 0.024965
UBAP2 ubiquitin associated protein 2 0.0247179
AHNAK AHNAK nucleoprotein 0.0245622
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0245179
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.0244328
SRPK2 SRSF protein kinase 2 0.0241737
SEC31A SEC31 homolog A (S. cerevisiae) 0.0241412
MED13 mediator complex subunit 13 0.0240934
LPP LIM domain containing preferred translocation partner in lipoma 0.0240669
SQSTM1 sequestosome 1 0.0236949
AKAP13 A kinase (PRKA) anchor protein 13 0.0236032
SEPTIN9 septin 9 0.0232041
TIMP2 TIMP metallopeptidase inhibitor 2 0.0228756
PICALM phosphatidylinositol binding clathrin assembly protein 0.0228663
NCAPG2 non-SMC condensin II complex, subunit G2 0.0226101
EIF4B eukaryotic translation initiation factor 4B 0.0224513
CUX1 cut-like homeobox 1 0.022439
TMF1 TATA element modulatory factor 1 0.0223758
TNIK TRAF2 and NCK interacting kinase 0.0223454
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.0223106
RCOR1 REST corepressor 1 0.0221547
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0219573
PDLIM5 PDZ and LIM domain 5 0.0219248
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.021802
DSCAM Down syndrome cell adhesion molecule 0.0217141
SPDYA speedy/RINGO cell cycle regulator family member A 0.0214918
CEP128 centrosomal protein 128kDa 0.0214679
AFDN afadin, adherens junction formation factor 0.02134
SETX senataxin 0.0212241
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0211856
TPM3 tropomyosin 3 0.0210781
OSBPL10 oxysterol binding protein-like 10 0.0207639
ARGLU1 arginine and glutamate rich 1 0.020585
ANKRD10 ankyrin repeat domain 10 0.0205396
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0205225
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0205103
GLS2 glutaminase 2 (liver, mitochondrial) 0.0205087
DOCK9 dedicator of cytokinesis 9 0.0204353
ANLN anillin, actin binding protein 0.020419
ACTN1 actinin, alpha 1 0.0204101
GPATCH2L G patch domain containing 2-like 0.0200684
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0198884
VMP1 vacuole membrane protein 1 0.0198725
EGFR epidermal growth factor receptor 0.0198578
ESYT2 extended synaptotagmin-like protein 2 0.0197836
KDM6A lysine (K)-specific demethylase 6A 0.0195758
RBM33 RNA binding motif protein 33 0.0194925
GOLGB1 golgin B1 0.0194229
ABR active BCR-related 0.0193707
LIMS1 LIM and senescent cell antigen-like domains 1 0.0191467
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.0191111
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0190722
ARHGAP9 Rho GTPase activating protein 9 0.0190563
GOLGA4 golgin A4 0.0189903
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.0189441
RBP1 retinol binding protein 1, cellular 0.0189028

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.341972
NKD1 naked cuticle homolog 1 (Drosophila) -0.262177
TMSB10 thymosin beta 10 -0.183725
RPS6 ribosomal protein S6 -0.12461
RPLP1 ribosomal protein, large, P1 -0.103178
MT2A metallothionein 2A -0.0874202
RPL32 ribosomal protein L32 -0.0812415
RPL12 ribosomal protein L12 -0.0792626
RPLP2 ribosomal protein, large, P2 -0.0721896
RPS24 ribosomal protein S24 -0.0708476
SYT1 synaptotagmin I -0.0658204
RPL19 ribosomal protein L19 -0.0647138
RPS19 ribosomal protein S19 -0.0642977
EGR1 early growth response 1 -0.0632952
VIM vimentin -0.0620256
RPS23 ribosomal protein S23 -0.0612911
RPL35A ribosomal protein L35a -0.0607835
RPL5 ribosomal protein L5 -0.060626
RPL23 ribosomal protein L23 -0.0602229
SOX4 SRY (sex determining region Y)-box 4 -0.0597068
PGK1 phosphoglycerate kinase 1 -0.0579784
RPL11 ribosomal protein L11 -0.0574399
ACTN4 actinin, alpha 4 -0.0565807
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0565696
RPS4X ribosomal protein S4, X-linked -0.0546531
EIF1 eukaryotic translation initiation factor 1 -0.0542721
RPS3 ribosomal protein S3 -0.0540984
RPLP0 ribosomal protein, large, P0 -0.0537966
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0536835
RPL18 ribosomal protein L18 -0.0492902
EZR ezrin -0.0489388
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0486077
RPL36 ribosomal protein L36 -0.0481304
RPL8 ribosomal protein L8 -0.0471063
RPS13 ribosomal protein S13 -0.0447054
CENPF centromere protein F, 350/400kDa -0.044184
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0433009
RPS21 ribosomal protein S21 -0.0432931
RPL34 ribosomal protein L34 -0.0432848
RPL37 ribosomal protein L37 -0.0432807
RPL26 ribosomal protein L26 -0.0421325
RPL36A ribosomal protein L36a -0.041588
RPL27A ribosomal protein L27a -0.0415285
RACK1 receptor for activated C kinase 1 -0.0413404
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0412976
TXNIP thioredoxin interacting protein -0.0411408
H3-3B H3.3 histone B -0.0405868
H1-0 H1.0 linker histone -0.0404315
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -0.0398097
RPL13A ribosomal protein L13a -0.0397468
RPL28 ribosomal protein L28 -0.0396787
LOC102724023 ES1 protein homolog, mitochondrial -0.0392425
RPS11 ribosomal protein S11 -0.0378477
RPS5 ribosomal protein S5 -0.0371423
TMEM123 transmembrane protein 123 -0.0361107
TPI1 triosephosphate isomerase 1 -0.0357848
RPL35 ribosomal protein L35 -0.0356257
CBX3 chromobox homolog 3 -0.0353924
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0352885
MT1X metallothionein 1X -0.035145
SLC38A1 solute carrier family 38, member 1 -0.0351225
MYL12B myosin, light chain 12B, regulatory -0.0350836
RPL7 ribosomal protein L7 -0.0349024
MKI67 marker of proliferation Ki-67 -0.0348435
RPL9 ribosomal protein L9 -0.0346054
HMGA1 high mobility group AT-hook 1 -0.0345282
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0344239
RPS12 ribosomal protein S12 -0.0341335
FOXP1 forkhead box P1 -0.0337249
RPS14 ribosomal protein S14 -0.0335273
OXR1 oxidation resistance 1 -0.0333239
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0327792
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0324923
EEF2 eukaryotic translation elongation factor 2 -0.0324785
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0320724
RPS20 ribosomal protein S20 -0.0317462
HMGB1 high mobility group box 1 -0.0317412
RPS29 ribosomal protein S29 -0.0316309
NACA nascent polypeptide-associated complex alpha subunit -0.0312739
RPS8 ribosomal protein S8 -0.0309848
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0309616
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0308046
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0307661
RPL31 ribosomal protein L31 -0.0299555
GARS1 glycyl-tRNA synthetase 1 -0.0298289
RPS15 ribosomal protein S15 -0.0297184
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -0.0297145
YBX1 Y box binding protein 1 -0.0296679
YBX3 Y box binding protein 3 -0.0293158
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0289752
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0289695
RPS27A ribosomal protein S27a -0.0286487
PFN1 profilin 1 -0.0285666
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0284514
TUBB tubulin, beta class I -0.0281949
DUSP6 dual specificity phosphatase 6 -0.0280902
RPS16 ribosomal protein S16 -0.0277818
SEC61G Sec61 gamma subunit -0.0277557
NIPBL Nipped-B homolog (Drosophila) -0.0275024
NAP1L1 nucleosome assembly protein 1-like 1 -0.0259924