| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cytarabine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cytarabine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MKI67 | marker of proliferation Ki-67 | 0.0805418 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0775371 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0681867 |
| TMEM41B | transmembrane protein 41B | 0.0648816 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0607688 |
| RPS12 | ribosomal protein S12 | 0.0557861 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0533605 |
| MED13L | mediator complex subunit 13-like | 0.0511271 |
| ANXA1 | annexin A1 | 0.049808 |
| DST | dystonin | 0.0484114 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0481508 |
| SET | SET nuclear proto-oncogene | 0.0478571 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0464999 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0451063 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0437477 |
| RPS2 | ribosomal protein S2 | 0.0411279 |
| YEATS2 | YEATS domain containing 2 | 0.0401102 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0400839 |
| VMP1 | vacuole membrane protein 1 | 0.0394908 |
| CPOX | coproporphyrinogen oxidase | 0.0392416 |
| NHSL1 | NHS-like 1 | 0.0391948 |
| XPO1 | exportin 1 | 0.038465 |
| NEK7 | NIMA-related kinase 7 | 0.0383725 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0381595 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0377914 |
| KIF5B | kinesin family member 5B | 0.0375968 |
| PUM2 | pumilio RNA-binding family member 2 | 0.037156 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0347037 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0345015 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0339896 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0338755 |
| THOC1 | THO complex 1 | 0.0333387 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0329435 |
| IL6ST | interleukin 6 signal transducer | 0.0313282 |
| KIF18B | kinesin family member 18B | 0.0312503 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0311358 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0309333 |
| DIAPH3 | diaphanous-related formin 3 | 0.0308631 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0308081 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0307563 |
| NCKAP1 | NCK-associated protein 1 | 0.0302928 |
| CIP2A | cellular inhibitor of PP2A | 0.0302138 |
| PDGFC | platelet derived growth factor C | 0.0299321 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0297052 |
| RPS7 | ribosomal protein S7 | 0.0287852 |
| TNPO1 | transportin 1 | 0.0287549 |
| ECT2 | epithelial cell transforming 2 | 0.0270803 |
| SBF2 | SET binding factor 2 | 0.0268734 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0268733 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0264365 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.026207 |
| RPS3 | ribosomal protein S3 | 0.0255652 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0255569 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0252834 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0251529 |
| MSH2 | mutS homolog 2 | 0.0249137 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0243824 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0243125 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0242287 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0239261 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0238513 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.023789 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0236274 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0235249 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0235115 |
| MMP12 | matrix metallopeptidase 12 | 0.0235029 |
| RNF13 | ring finger protein 13 | 0.0234387 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0233883 |
| STAG2 | stromal antigen 2 | 0.0232358 |
| HLTF | helicase-like transcription factor | 0.0232273 |
| MGAT4C | MGAT4 family, member C | 0.0231471 |
| WDR43 | WD repeat domain 43 | 0.0230929 |
| CCDC14 | coiled-coil domain containing 14 | 0.0230666 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.022878 |
| GASK1B | golgi associated kinase 1B | 0.0226352 |
| NUP153 | nucleoporin 153kDa | 0.0224656 |
| CEP192 | centrosomal protein 192kDa | 0.0224629 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0224049 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0222256 |
| ETNK1 | ethanolamine kinase 1 | 0.0221989 |
| ZNF292 | zinc finger protein 292 | 0.0221385 |
| CDK19 | cyclin-dependent kinase 19 | 0.0221315 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.022128 |
| TPX2 | TPX2, microtubule-associated | 0.0221243 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0216828 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0216339 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0212598 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0211493 |
| SFXN1 | sideroflexin 1 | 0.0211392 |
| HDGF | hepatoma-derived growth factor | 0.0211106 |
| RASA2 | RAS p21 protein activator 2 | 0.0210103 |
| PNN | pinin, desmosome associated protein | 0.0209966 |
| H1-4 | H1.4 linker histone, cluster member | 0.0209289 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0209171 |
| R3HDM1 | R3H domain containing 1 | 0.0209004 |
| CEP170 | centrosomal protein 170kDa | 0.020896 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0205628 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0203664 |
| NDC80 | NDC80 kinetochore complex component | 0.0203492 |
| FANCL | Fanconi anemia, complementation group L | 0.0202875 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.188405 |
| VIM | vimentin | -0.178864 |
| TMSB10 | thymosin beta 10 | -0.148037 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.147233 |
| NLGN1 | neuroligin 1 | -0.127244 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.118272 |
| RAB7A | RAB7A, member RAS oncogene family | -0.112452 |
| HMGA2 | high mobility group AT-hook 2 | -0.0845213 |
| EGR1 | early growth response 1 | -0.0813336 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0735696 |
| FTL | ferritin, light polypeptide | -0.0720545 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0709382 |
| PCBP2 | poly(rC) binding protein 2 | -0.0640507 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0615732 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0596786 |
| ACTG1 | actin gamma 1 | -0.0589809 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0582274 |
| INTS6 | integrator complex subunit 6 | -0.0564318 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0552611 |
| TPI1 | triosephosphate isomerase 1 | -0.0541404 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.05308 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0518638 |
| PFN1 | profilin 1 | -0.0506089 |
| ADIPOR2 | adiponectin receptor 2 | -0.0498599 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0491518 |
| RPLP0 | ribosomal protein, large, P0 | -0.0485762 |
| HMGA1 | high mobility group AT-hook 1 | -0.0483478 |
| NABP1 | nucleic acid binding protein 1 | -0.046633 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0459051 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.044347 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0436208 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.043485 |
| ZNF804A | zinc finger protein 804A | -0.0432531 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0424264 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0420846 |
| CCND1 | cyclin D1 | -0.041896 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0416063 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0405285 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0390853 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0376367 |
| TUBA1B | tubulin, alpha 1b | -0.0371769 |
| HLA-A | major histocompatibility complex, class I, A | -0.0367476 |
| LRRC23 | leucine rich repeat containing 23 | -0.0363097 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0353604 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0352018 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0347938 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0347634 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0346878 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0345329 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0343223 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0336034 |
| YBX1 | Y box binding protein 1 | -0.0333538 |
| CCN2 | cellular communication network factor 2 | -0.0327457 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0320276 |
| RPL35A | ribosomal protein L35a | -0.031974 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0318601 |
| GOLGB1 | golgin B1 | -0.031352 |
| GCG | glucagon | -0.0308816 |
| MAP1B | microtubule-associated protein 1B | -0.0305271 |
| RPL27A | ribosomal protein L27a | -0.029502 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0293845 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.029226 |
| ATF6 | activating transcription factor 6 | -0.0291437 |
| SETX | senataxin | -0.0291066 |
| RPLP1 | ribosomal protein, large, P1 | -0.0290531 |
| POTEF | POTE ankyrin domain family, member F | -0.0290085 |
| ANKRD17 | ankyrin repeat domain 17 | -0.028708 |
| SCFD1 | sec1 family domain containing 1 | -0.0282086 |
| TBCA | tubulin folding cofactor A | -0.0279719 |
| LDHA | lactate dehydrogenase A | -0.0277718 |
| UBC | ubiquitin C | -0.0271687 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0267397 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0266377 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0262776 |
| RNF213 | ring finger protein 213 | -0.0261969 |
| H1-0 | H1.0 linker histone | -0.0261169 |
| CMIP | c-Maf inducing protein | -0.0260982 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0259233 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0253948 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0250065 |
| RPS24 | ribosomal protein S24 | -0.0250038 |
| SKIL | SKI-like proto-oncogene | -0.0240404 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0239182 |
| EHBP1 | EH domain binding protein 1 | -0.0237461 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0236502 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0235388 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0233197 |
| VAT1 | vesicle amine transport 1 | -0.0232884 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.023234 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0230985 |
| ACLY | ATP citrate lyase | -0.0226425 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.022458 |
| MORF4L2 | mortality factor 4 like 2 | -0.0224281 |
| HDLBP | high density lipoprotein binding protein | -0.0222562 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.022204 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0221663 |
| CALR | calreticulin | -0.0217825 |
| CANX | calnexin | -0.0217391 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0216013 |
| BCL6 | B-cell CLL/lymphoma 6 | -0.0210154 |
